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Covalent Modifier Discovery Using Hydrogen/Deuterium Exchange-Mass SpectrometryJOURNAL OF MEDICINAL CHEMISTRYIF6.82023-03-300PRE
Hydroxylation and dechlorination of 3,3′,4,4′-tetrachlorobiphenyl (CB77) by rat and human CYP1A1s and critical roles of amino acids composing their substrate-binding cavitySCIENCE OF THE TOTAL ENVIRONMENTIF82022-09-012OAAI
Differences in Enantioselective Hydroxylation of 2,2′,3,6-Tetrachlorobiphenyl (CB45) and 2,2',3,4',6-Pentachlorobiphenyl (CB91) by Human and Rat CYP2B SubfamiliesENVIRONMENTAL SCIENCE & TECHNOLOGYIF11.32022-07-083OA
Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signalingFREE RADICAL BIOLOGY AND MEDICINEIF8.22020-08-018OAAI
Insights into PPARγ Phosphorylation and Its Inhibition MechanismJOURNAL OF MEDICINAL CHEMISTRYIF6.82020-04-0223OAAI
Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target ProteinsCELL CHEMICAL BIOLOGYIF7.22020-03-0125OAAI
Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytesFASEB JOURNALIF4.22020-02-0331OAAI
Design and synthesis of selective CYP1B1 inhibitor via dearomatization of α-naphthoflavoneBIOORGANIC & MEDICINAL CHEMISTRYIF32019-01-0121PREAI
Construction of a series of intermediates in the β-oxidation pathway from THA to EPA via DHA in free acid formBIOORGANIC & MEDICINAL CHEMISTRYIF32018-08-016PREAI
Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic LigandsJOURNAL OF MEDICINAL CHEMISTRYIF6.82018-06-2321PREAI
On-site reaction for PPARγ modification using a specific bifunctional ligandBIOORGANIC & MEDICINAL CHEMISTRYIF32017-12-016PREAI
Vitamin D Analogues with a p-Hydroxyphenyl Group at the C25 Position: Crystal Structure of Vitamin D Receptor Ligand-Binding Domain Complexed with the Ligand Explains the Mechanism Underlying Full Antagonistic ActionJOURNAL OF MEDICINAL CHEMISTRYIF6.82017-10-1011PREAI
Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by a Combination Andlysis of MD Simulations and SAXS ExperimentsBIOPHYSICAL JOURNALIF3.12017-02-010OAAI
SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinityBIOORGANIC & MEDICINAL CHEMISTRYIF32017-01-0110PREAI
Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular DynamicsJOURNAL OF MEDICINAL CHEMISTRYIF6.82016-08-2624PREAI
Structural Determinants of the Position of 2,3′,4,4′,5-Pentachlorobiphenyl (CB118) Hydroxylation by Mammalian Cytochrome P450 MonooxygenasesTOXICOLOGICAL SCIENCESIF4.12016-05-1316OA
Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activityBIOORGANIC & MEDICINAL CHEMISTRYIF32015-11-0112OAAI
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