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R

Roberto Nitsch

AstraZeneca
H指数:22
被引数:2,521

个人简介

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教育背景

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工作经历

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荣誉奖项

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Unveiling the cut-and-repair cycle of designer nucleases in human stem and T cells via CLEAR-time dPCR

通过清除时间dPCR揭示人类干细胞和T细胞中设计核酸酶的切割和修复周期

Nature Communications
IF15.7
2025-11-030
OAAI
Nathan White; John Alexander Chalk; Yi-Ting Hu; Samuel Mark Pins; Chinnu Rose Joseph; Panagiotis Antoniou; Sandra Wimberger; Stina Svensson; Soraia Patricia Caetano-Silva; Anne Charlotte Adriane Mudde; Rajeev Rai; Sridhar Selvaraj; William Nelson Feist; Marianna Romito; Grzegorz Sienski; Roberto Nitsch; Claire Booth; Giorgia Santilli; Alessia Cavazza; Matthew Hebden Porteus; Marcello Maresca; Adrian James Thrasher; Giandomenico Turchiano
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery
NATURE COMMUNICATIONS
IF15.7
2020-09-2935
OAAI
Lundin, Anders; Porritt, Michelle J.; Jaiswal, Himjyot; Seeliger, Frank; Johansson, Camilla; Bidar, Abdel Wahad; Badertscher, Lukas; Wimberger, Sandra; Davies, Emma J.; Hardaker, Elizabeth; Martins, Carla P.; James, Emily; Admyre, Therese; Taheri-Ghahfarokhi, Amir; Bradley, Jenna; Schantz, Anna; Alaeimahabadi, Babak; Clausen, Maryam; Xu, Xiufeng; Mayr, Lorenz M.; Nitsch, Roberto; Bohlooly-Y, Mohammad; Barry, Simon T.; Maresca, Marcello
HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases
CANCER RESEARCH
IF16.6
2020-07-1522
OAAI
Kogler, Melanie; Tortola, Luigi; Negri, Gian Luca; Leopoldi, Alexandra; El-Naggar, Amal M.; Mereiter, Stefan; Gomez-Diaz, Carlos; Nitsch, Roberto; Tortora, Davide; Kavirayani, Anoop M.; Gapp, Bianca, V; Rao, Shuan; Uribesalgo, Iris; Hoffmann, David; Cikes, Domagoj; Novatchkova, Maria; Williams, David A.; Trent, Jeffrey M.; Ikeda, Fumiyo; Daugaard, Mads; Hagelkruys, Astrid; Sorensen, Poul H.; Penninger, Josef M.
HACE1 deficiency leads to structural and functional neurodevelopmental defects
NEUROLOGY-GENETICS
IF3.7
2019-06-0131
OAAI
Nagy, Vanja; Hollstein, Ronja; Pai, Tsung-Pin; Herde, Michel K.; Buphamalai, Pisanu; Moeseneder, Paul; Lenartowicz, Ewelina; Kavirayani, Anoop; Korenke, Georg Christoph; Kozieradzki, Ivona; Nitsch, Roberto; Cicvaric, Ana; Quiroga, Francisco J. Monje; Deardorff, Matthew A.; Bedoukian, Emma C.; Li, Yun; Yigit, Goekhan; Menche, Joerg; Percin, E. Ferda; Wollnik, Bernd; Henneberger, Christian; Kaiser, Frank J.; Penninger, Josef M.
Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype

在人源化小鼠模型中使用CRISPR/Cas9进行治疗性基因组编辑可改善 α1-抗胰蛋白酶缺乏症表型

EBIOMEDICINE
IF10.8
2018-03-0157
OAAI
Bjursell, Mikael; Porritt, Michelle J.; Ericson, Elke; Taheri-Ghahfarokhi, Amir; Clausen, Maryam; Magnusson, Lisa; Admyre, Therese; Nitsch, Roberto; Mayr, Lorenz; Aasehaug, Leif; Seeliger, Frank; Maresca, Marcello; Bohlooly-Y, Mohammad; Wiseman, John
The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate (vol 15, pg 1481, 2016)
CELL REPORTS
IF6.9
2016-09-0116
OAAI
Tortola, Luigi; Nitsch, Roberto; Bertrand, Mathieu J. M.; Kogler, Melanie; Redouane, Younes; Kozieradzki, Ivona; Uribesalgo, Iris; Fennell, Lilian M.; Daugaard, Mads; Klug, Helene; Wirnsberger, Gerald; Wimmer, Reiner; Perlot, Thomas; Sarao, Renu; Rao, Shuan; Hanada, Toshikatsu; Takahashi, Nozomi; Kernbauer, Elisabeth; Demiroz, Duygu; Lang, Michaela; Superti-Furga, Giulio; Decker, Thomas; Pichler, Andrea; Ikeda, Fumiyo; Kroemer, Guido; Vandenabeele, Peter; Sorensen, Poul H.; Penninger, Josef M.
The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate
CELL REPORTS
IF6.9
2016-05-0142
OAAI
Tortola, Luigi; Nitsch, Roberto; Bertrand, Mathieu J. M.; Kogler, Melanie; Redouane, Younes; Kozieradzki, Ivona; Uribesalgo, Iris; Fennell, Lilian M.; Daugaard, Mads; Klug, Helene; Wirnsberger, Gerald; Wimmer, Reiner; Perlot, Thomas; Sarao, Renu; Rao, Shuan; Hanada, Toshikatsu; Takahashi, Nozomi; Kernbauer, Elisabeth; Demiroez, Duygu; Superti-Furga, Giulio; Decker, Thomas; Pichler, Andrea; Ikeda, Fumiyo; Kroemer, Guido; Vandenabeele, Peter; Sorensen, Poul H.; Penninger, Josef M.
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2014-02-1087
OAAI
Rotblat, Barak; Southwell, Amber L.; Ehrnhoefer, Dagmar E.; Skotte, Niels H.; Metzler, Martina; Franciosi, Sonia; Leprivier, Gabriel; Somasekharan, Syam Prakash; Barokas, Adi; Deng, Yu; Tang, Tiffany; Mathers, Joan; Cetinbas, Naniye; Daugaard, Mads; Kwok, Brian; Li, Liheng; Carnie, Christopher J.; Fink, Dieter; Nitsch, Roberto; Galpin, Jason D.; Ahern, Christopher A.; Melino, Gerry; Penninger, Josef M.; Hayden, Michael R.; Sorensen, Poul H.
A dual role for autophagy in a murine model of lung cancer

自噬在小鼠肺癌模型中的双重作用

NATURE COMMUNICATIONS
IF15.7
2014-01-20390
OA
Rao, Shuan; Tortola, Luigi; Perlot, Thomas; Wirnsberger, Gerald; Novatchkova, Maria; Nitsch, Roberto; Sykacek, Peter; Frank, Lukas; Schramek, Daniel; Komnenovic, Vukoslav; Sigl, Verena; Aumayr, Karin; Schmauss, Gerald; Fellner, Nicole; Handschuh, Stephan; Gloesmann, Martin; Pasierbek, Pawel; Schlederer, Michaela; Resch, Guenter P.; Ma, Yuting; Yang, Heng; Popper, Helmuth; Kenner, Lukas; Kroemer, Guido; Penninger, Josef M.

研究方向

暂未获取到该数据
J
Josef Penninger
H 指数:174论文数:1,635被引数:14.4万
M
Mads Daugaard
H 指数:37论文数:247被引数:6,681
P
Poul H. Sorensen
H 指数:84论文数:636被引数:2.7万
L
Luigi Tortola
H 指数:22论文数:67被引数:2,537
S
Shuan Rao
H 指数:31论文数:139被引数:1.1万
M
Marcello Maresca
H 指数:26论文数:79被引数:3,140
M
Mariastella Zannini
H 指数:31论文数:78被引数:3,568
G
Gerald Wirnsberger
H 指数:24论文数:48被引数:5,782
F
Fumiyo Ikeda
H 指数:36论文数:92被引数:1.0万
I
I. Kozieradzki
H 指数:36论文数:129被引数:9,955