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B

Brian L. West

daiichi sankyo company limited
H指数:70
被引数:2.8万

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Phase 1b/2 study of orally administered pexidartinib in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma
NEURO-ONCOLOGY ADVANCES
IF4.1
2024-11-220
OAAI
Mendez, Joe S.; Cohen, Adam L.; Eckenstein, Midori; Jensen, Randy L.; Burt, Lindsay M.; Salzman, Karen L.; Chamberlain, Marc; Hsu, Henry H.; Hutchinson, Marguerite; Iwamoto, Fabio; Ligon, Keith L.; Mrugala, Maciej M.; Pelayo, Michael; Plotkin, Scott R.; Puduvalli, Vinay K.; Raizer, Jeffrey; Reardon, David A.; Sterba, Michael; Walbert, Tobias; West, Brian L.; Wong, Eric T.; Zhang, Chao; Colman, Howard
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions

小胶质细胞通过嘌呤能作用调节血流，神经血管耦合和灌注不足

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2022-02-24109
OAAI
Csaszar, Eszter; Lenart, Nikolett; Cserep, Csaba; Koernyei, Zsuzsanna; Fekete, Rebeka; Posfai, Balazs; Balazsfi, Diana; Hangya, Balazs; Schwarcz, Anett D.; Szabadits, Eszter; Szoellosi, David; Szigeti, Krisztian; Mathe, Domokos; West, Brian L.; Sviatko, Katalin; Bras, Ana Rita; Mariani, Jean-Charles; Kliewer, Andrea; Lenkei, Zsolt; Hricisak, Laszlo; Benyo, Zoltan; Baranyi, Maria; Sperlagh, Beata; Menyhart, Akos; Farkas, Eszter; Denes, Adam
A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/refractory FLT3-ITD-mutant acute myeloid leukemia

口服FLT3抑制剂pexidartinib治疗复发/难治性FLT3-ITD-mutant急性髓系白血病的1/2期研究

BLOOD ADVANCES
IF7.1
2020-04-2433
OAAI
Smith, Catherine C.; Levis, Mark J.; Frankfurt, Olga; Pagel, John M.; Roboz, Gail J.; Stone, Richard M.; Wang, Eunice S.; Severson, Paul L.; West, Brian L.; Le, Mai H.; Kayser, Sabine; Lam, Bao; Hsu, Henry H.; Zhang, Chao; Bollag, Gideon; Perl, Alexander E.
Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model
NATURE COMMUNICATIONS
IF15.7
2019-08-21574
OAAI
Spangenberg, Elizabeth; Severson, Paul L.; Hohsfield, Lindsay A.; Crapser, Joshua; Zhang, Jiazhong; Burton, Elizabeth A.; Zhang, Ying; Spevak, Wayne; Line, Jack; Phan, Nicole Y.; Habets, Gaston; Rymar, Andrey; Tsang, Garson; Walters, Jason; Nespi, Marika; Singh, Parmveer; Broome, Stephanie; Ibrahim, Prabha; Zhang, Chao; Bollag, Gideon; West, Brian L.; Green, Kim N.
Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors

晚期实体瘤患者CSF-1R抑制剂pexidartinib (PLX3397) 和紫杉醇联合治疗的Ib期研究

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY
IF4.2
2019-06-21102
OAAI
Wesolowski, Robert; Sharma, Neelesh; Reebel, Laura; Rodal, Mary Beth; Peck, Alexandra; West, Brian L.; Marimuthu, Adhirai; Severson, Paul; Karlin, David A.; Dowlati, Afshin; Le, Mai H.; Coussens, Lisa M.; Rugo, Hope S.
The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma
JCI INSIGHT
IF6.1
2018-07-2531
OA
Giricz, Orsi; Mo, Yongkai; Dahlman, Kimberly B.; Cotto-Rios, Xiomaris M.; Vardabasso, Chiara; Hoa Nguyen; Matusow, Bernice; Bartenstein, Matthias; Polishchuk, Veronika; Johnson, Douglas B.; Bhagat, Tushar D.; Shellooe, Rafe; Burton, Elizabeth; Tsai, James; Zhang, Chao; Habets, Gaston; Greally, John M.; Yu, Yiting; Kenny, Paraic A.; Fields, Gregg B.; Pradhan, Kith; Stanley, E. Richard; Bernstein, Emily; Bollag, Gideon; Gavathiotis, Evripidis; West, Brian L.; Sosman, Jeffrey A.; Verma, Amit K.
Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms
ACTA NEUROPATHOLOGICA
IF9.3
2018-07-19119
OAAI
Fekete, Rebeka; Cserep, Csaba; Lenart, Nikolett; Toth, Krisztina; Orsolits, Barbara; Martinecz, Bernadett; Mehes, Elod; Szabo, Balint; Nemeth, Valeria; Gonci, Balazs; Sperlagh, Beata; Boldogkoi, Zsolt; Kittel, Agnes; Baranyi, Maria; Ferenczi, Szilamer; Kovacs, Krisztina; Szalay, Gergely; Rozsa, Balazs; Webb, Connor; Kovacs, Gabor G.; Hortobagyi, Tibor; West, Brian L.; Kornyei, Zsuzsanna; Denes, Adam
Microglia ablation alleviates myelin-associated catatonic signs in mice
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2017-12-1886
OA
Janova, Hana; Arinrad, Sahab; Balmuth, Evan; Mitjans, Marina; Hertel, Johannes; Habes, Mohamad; Bittner, Robert A.; Pan, Hong; Goebbels, Sandra; Begemann, Martin; Gerwig, Ulrike C.; Langner, Soenke; Werner, Hauke B.; Kittel-Schneider, Sarah; Homuth, Georg; Davatzikos, Christos; Voelzke, Henry; West, Brian L.; Reif, Andreas; Grabe, Hans Joergen; Boretius, Susann; Ehrenreich, Hannelore; Nave, Klaus-Armin

研究方向

暂未获取到该数据
G
Gideon Bollag
H 指数:67论文数:360被引数:3.0万
H
Hoa Nguyen
H 指数:27论文数:62被引数:1.0万
G
Gaston Habets
H 指数:21论文数:87被引数:8,847
R
Rafe Shellooe
H 指数:10论文数:48被引数:4,643
A
Adhirai Marimuthu
H 指数:19论文数:52被引数:6,056
B
Bernice Matusow
H 指数:10论文数:56被引数:2,952
P
Prabha N. Ibrahim
H 指数:19论文数:78被引数:7,860
K
Kam Y. J. Zhang
H 指数:47论文数:218被引数:1.2万
E
Elizabeth A. Burton
H 指数:35论文数:93被引数:8,597
K
Kim N. Green
H 指数:60论文数:180被引数:2.0万