Aseem Z. Ansari - Publications, H-index & Citations

Aseem Z. Ansari

St. Jude Children's Research Hospital

44H指数

123论文数

6.8K被引数

收录论文 73

发表时间

BRD4 recruitment into HP1 condensates desilences transcription without erasure of repressive chromatin 溴结构域蛋白4招募进入H1凝集体在不擦除抑制性染色质的情况下去沉默转录

Nature Cell Biology

IF19.1

2026-08-05

PREAI

Christopher J. Brandon; Sarah Robinson-Thiewes; Mangesh Kaulage; Wojciech Rosikiewicz; Matthew J. Cuneo; Joseph Brett; Jindpreet Kandola; Walter H. Lang; Jonathan Low; Ashraf Mohammed; Adithi Danda; Sam Rider; Marcus Valentine; Jason Ochoada; Brandon Young; Theresa Nguyen; Sandra J. Kietlinska; Aaron B. Taylor; Burkhard Hoeckendorf; Patrick Rodrigues; Wenwei Lin; Khaled Khairy; Beisi Xu; Anang A. Shelat; Taosheng Chen; Tanja Mittag; Aseem Z. Ansari

Label-Free High-Throughput Screening of CYP3A4 Inhibitors Using Acoustic Ejection Mass Spectrometry 无标记高通量筛选CYP3A4抑制剂，采用声波喷射质谱法

Analytical Chemistry

IF6.7

2026-04-17

PREAI

Mary Ashley Rimmer; Jingheng Wang; Tharindu A. Ranathunge; Zhe Shi; Yong Li; DongGeun Lee; Sergio C. Chai; Wenwei Lin; Nathaniel R. Twarog; Aseem Z. Ansari; Anang A. Shelat; Brandon M. Young; Taosheng Chen; Lei Yang

Direct targeting and regulation of RNA polymerase II by cell signaling kinases 细胞信号激酶对RNA聚合酶II的直接靶向与调控

Science

IF45.8

2025-11-06

PREAI

Preeti Dabas; Meritxell B. Cutrona; Wojciech Rosikiewicz; Ryan P. Kempen; Patrick Rodrigues; John Bowling; Mollie S. Prater; Walter H. Lang; Adithi Danda; Zhi Yuan; Beisi Xu; Shondra M. Pruett-Miller; Gang Wu; Taosheng Chen; Aseem Z. Ansari

Positional isomers of Indolyl-benzodiazepines display dissimilar binding and recruitment of BET transcriptional regulators to targeted genomic loci 吲哚-苯二氮䓬类化合物的位置异构体表现出对靶向基因组位点上的BET转录调控因子的不同结合与募集活性。

Bioorganic Chemistry

IF4.7

2025-08-05

PREAI

Nilanjana Chowdhury; Stanley Nithianantham; Sudip Dey; Rafi Mohammed; Ashraf Mohammed; Kelly Churion; Walter Lang; Sarah Young; Steven J. Philips; Sourav Das; Bedabrata Ray; Anang Shelat; Marcus Fischer; Aseem Z. Ansari; Parasuraman Jaisankar

Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function 调和关于凝聚体和可溶性复合物在转录因子功能中作用的竞争模型

Molecular Cell

IF16.6

2025-07-03

OAAI

Anne Bremer; Walter H. Lang; Ryan P. Kempen; Kumari Sweta; Aaron B. Taylor; Madeleine B. Borgia; Aseem Z. Ansari; Tanja Mittag

A Goldilocks Zone for Recruiting BET Proteins with Bromodomain-1-Selective Ligands

ACS CHEMICAL BIOLOGY

IF3.8

2024-10-14

PREAI

Mohammed, Ashraf; Churion, Kelly; Danda, Adithi; Philips, Steven J.; Ansari, Aseem Z.

ZFTA FUSION ONCOPROTEINS DRIVE ONCOGENESIS THROUGH ASSEMBLY OF BIOMOLECULAR CONDENSATES

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Varadharajan, Srinidhi; Arabzade, Amir; Shirnekhi, Hazheen K.; Ippagunta, Siri; Laboe, Nic; Gee, David; Emanus, Erik; Kardian, Alisha; Phillips, Aaron H.; Tripathi, Swarnendu; Shirinifard, Abbas; Petersen, Becky; King, Sharon; Stabley, Daniel; Pitre, Aaron; Campbell, George; Park, Cheon-Gil; Durbin, Adam D.; Qi, Jun; Bertrand, Kelsey; Taylor, Michael D.; Northcott, Paul A.; Deneen, Benjamin; Ansari, Aseem Z.; Kriwacki, Richard W.; Mack, Stephen C.

Using synthetic genome readers/regulators to interrogate chromatin processes: A brief review

METHODS

IF4.3

2024-05-01

PREAI

Philips, Steven J.; Danda, Adithi; Ansari, Aseem Z.

In search of chemical rationales

NATURE CHEMICAL BIOLOGY

IF13.7

2023-11-29

PREAI

Ansari, Aseem Z.

Domain-Selective BET Ligands Yield Next-Generation Synthetic Genome Readers/Regulators with Nonidentical Cellular Functions

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-11-03

PREAI

Mohammed, Ashraf; Waddell, M. Brett; Sutkeviciute, Ieva; Danda, Adithi; Philips, Steven J.; Lang, Walter; Slavish, P. Jake; Kietlinska, Sandra J.; Kaulage, Mangesh; Sourav, Das; Ansari, Aseem Z.

Hidden modes of DNA binding by human nuclear receptors

NATURE COMMUNICATIONS

IF15.7

2023-07-13

OAAI

Bhimsaria, Devesh; Rodriguez-Martinez, Jose A.; Mendez-Johnson, Jacqui L.; Ghoshdastidar, Debostuti; Varadarajan, Ashwin; Bansal, Manju; Daniels, Danette L.; Ramanathan, Parameswaran; Ansari, Aseem Z.

Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

221

OAAI

Liu, Y; Kung, C; Fishburn, J; Ansari, AZ; Shokat, KM; Hahn, S

The Phantom Mark: Enigmatic roles of phospho-Threonine 4 modification of the C-terminal domain of RNA polymerase II

WILEY INTERDISCIPLINARY REVIEWS-RNA

IF4.8

2023-01-06

OAAI

Kempen, Ryan P.; Dabas, Preeti; Ansari, Aseem Z.

S1-END-seq reveals DNA secondary structures in human cells

MOLECULAR CELL

IF16.6

2022-10-01

OAAI

Matos-Rodrigues, Gabriel; van Wietmarschen, Niek; Wu, Wei; Tripathi, Veenu; Koussa, Natasha C.; Pavani, Raphael; Nathan, William J.; Callen, Elsa; Belinky, Frida; Mohammed, Ashraf; Napierala, Marek; Usdin, Karen; Ansari, Aseem Z.; Mirkin, Sergei M.; Nussenzweig, Andre

Combinatorial bZIP dimers display complex DNA-binding specificity landscapes

ELIFE

IF0

2022-04-01

129

PREAI

Rodriguez-Martinez, Jose A.; Reinke, Aaron W.; Bhimsaria, Devesh; Keating, Amy E.; Ansari, Aseem Z.

Fusion proteins form onco-condensates

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-06-23

PREAI

Mittag, Tanja; Ansari, Aseem Z.

Blocking the Enablers: Selective Inhibition of CDK9 Reins in an Unchecked Master Regulator

CELL CHEMICAL BIOLOGY

IF7.2

2021-02-01

PREAI

Ansari, Aseem Z.

De novo design of programmable inducible promoters

NUCLEIC ACIDS RESEARCH

IF13.1

2019-09-25

OAAI

Liu, Xiangyang; Gupta, Sanjan T. P.; Bhimsaria, Devesh; Reed, Jennifer L.; Rodriguez-Martinez, Jose A.; Ansari, Aseem Z.; Raman, Srivatsan

A chemoprobe tracks its target

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-05-01

OAAI

Ansari, Aseem Z.

Noncanonical CTD kinases regulate RNA polymerase II in a gene-class-specific manner

NATURE CHEMICAL BIOLOGY

IF13.7

2018-12-31

OAAI

Nemec, Corey M.; Singh, Amit K.; Ali, Asfa; Tseng, Sandra C.; Syal, Kirtimaan; Ringelberg, Kennedy J.; Ho, Yi-Hsuan; Hintermair, Corinna; Ahmad, Mohammad Faiz; Kar, Rajesh Kumar; Gasch, Audrey P.; Akhtar, Md Sohail; Eick, Dirk; Ansari, Aseem Z.

研究方向