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H

Holly Holliday

children's cancer institute
H指数:15
被引数:1,270

个人简介

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教育背景

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工作经历

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荣誉奖项

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Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma

联合抑制FACT和BET破坏转录以抑制弥漫性中线胶质瘤小鼠模型的肿瘤生长

Science Translational Medicine
IF14.6
2026-01-140
PRE
Holliday, Holly; Khan, Aaminah; Ehteda, Anahid; Nguyen, Hieu; Ross, Samuel E.; Jayatilleke, Nisitha; Gopalakrishnan, Anjana; Wang, Eyden; Sanguino, Yolanda Colino; Kavanagh, Daisy; Guo, Xinyi; Liu, Jie; Lawrence, David; Sun, Claire X.; Lehmann, Rebecca; Ip, Chi Kin; Lee, Alvin; Rangel-Sanchez, Laura; Li, Wenyan; Salomon, Robert; Firestein, Ron; Weatheritt, Robert J.; Valdes-Mora, Fatima; Dinger, Marcel E.; Phoenix, Timothy N.; Mayoh, Chelsea; Rayner, Benjamin S.; Tsoli, Maria; Ziegler, David S.
The development of ACT001 with Mcl-1 inhibitors as a novel combination therapy for the treatment of paediatric diffuse midline glioma

ACT001与Mcl-1抑制剂联合开发作为一种新型联合疗法，用于治疗儿童弥漫性中线胶质瘤

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Lawrence, David; Upton, Dannielle; Tax, Gabor; Holliday, Holly; Ung, Caitlin; Gopalakrishnan, Anjana; Liu, Jie; Dolman, M. Emmy M.; Mao, Jie; Sivanathan, Acadia; Cai, Dongpo Doug; Su, Steven Yung-Chang; Rayner, Benjamin Rayner; Tsoli, Maria; Ziegler, David S.
CHROMATIN REMODELING WITH COMBINED FACT AND BET INHIBITION DISRUPTS ONCOGENIC TRANSCRIPTION IN DIFFUSE MIDLINE GLIOMA

联合FACT和BET抑制的染色质重塑破坏弥漫性中线胶质瘤中的致癌转录

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Holliday, Holly; Khan, Aaminah; Ehteda, Anahid; Nguyen, Hieu; Ross, Samuel; Jayatilleke, Nisitha; Gopalakrishnan, Anjana; Wang, Eyden; Guo, Xinyi; Sanguino, Yolanda Colino; Kavanagh, Daisy; Liu, Jie; Lawrence, David; Sun, Claire; Lehmann, Rebecca; Ip, Chi Kin; Lee, Alvin; Li, Wenyan; Salomon, Robert; Firestein, Ron; Weatheritt, Robert; Valdes-Mora, Fatima; Dinger, Marcel; Phoenix, Timothy; Mayoh, Chelsea; Rayner, Benjamin; Tsoli, Maria; Ziegler, David
Germline analysis of an international cohort of pediatric diffuse midline glioma patients

对国际队列儿童弥漫性中线胶质瘤患者的生殖系分析

NEURO-ONCOLOGY
IF13.4
2025-03-120
PRE
Marion K Mateos; Pamela Ajuyah; Noemi Fuentes-Bolanos; Sam El-Kamand; Paulette Barahona; Ann-Kristin Altekoester; Chelsea Mayoh; Holly Holliday; Jie Liu; Louise Cui; Elke Pfaff; Alan Mackay; Adam C Resnick; Mark Pinese; Loretta M S Lau; Dong-Anh Khuong-Quang; Kimberly Dias; Catherine Goudie; Alison Salkeld; Jo Lynne Rokita; David T W Jones; Nikoleta Juretic; Elisha Hayden; Stefan M Pfister; Christof M Kramm; Mirjam Blattner-Johnson; Nada Jabado; Maria Tsoli; Orazio Vittorio; Sabine Mueller; Yiran Guo; Katherine Tucker; Sebastian M Waszak; Sebastien Perreault; Chris Jones; Marie Wong-Erasmus; Mark J Cowley; David S Ziegler
High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic

高通量体外药物筛选和体内研究将fenretinide确定为一种能够穿透血脑屏障的DMG治疗药物。

NEURO-ONCOLOGY
IF13.4
2025-02-120
PRE
Upton, Dannielle H.; Liu, Jie; George, Sandra M.; Valvi, Santosh; Ung, Caitlin; Rayner, Benjamin S.; Gopalakrishnan, Anjana; Pandher, Ruby; Khan, Aaminah; Venkat, Pooja; Mayoh, Chelsea; Holliday, Holly; Yeung, Nicole; Nguyen, Hieu; Franshaw, Laura; Ehteda, Anahid; Shen, Han; Farruggia, Giovanna; Orienti, Isabella; Reynolds, C. Patrick; Tsoli, Maria; Ziegler, David S.
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response

暂时分辨的蛋白质组学将nidogen-2鉴定为胰腺癌的共靶标，其调节纤维化和治疗反应

SCIENCE ADVANCES
IF12.5
2024-07-052
OAAI
Pereira, Brooke A.; Ritchie, Shona; Chambers, Cecilia R.; Gordon, Katie A.; Magenau, Astrid; Murphy, Kendelle J.; Nobis, Max; Tyma, Victoria M.; Liew, Ying Fei; Lucas, Morghan C.; Naeini, Marjan M.; Barkauskas, Deborah S.; Chacon-Fajardo, Diego; Howell, Anna E.; Parker, Amelia L.; Warren, Sean C.; Reed, Daniel A.; Lee, Victoria; Metcalf, Xanthe L.; Lee, Young Kyung; O'Regan, Luke P.; Zhu, Jessie; Trpceski, Michael; Fontaine, Angela R. M.; Stoehr, Janett; Rouet, Romain; Lin, Xufeng; Chitty, Jessica L.; Porazinski, Sean; Wu, Sunny Z.; Filipe, Elysse C.; Cadell, Antonia L.; Holliday, Holly; Yang, Jessica; Papanicolaou, Michael; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Vennin, Claire; Yin, Julia; Dew, Alysha B.; Mcmillan, Paul J.; Goldstein, Leonard D.; Deveson, Ira W.; Croucher, David R.; Samuel, Michael S.; Sim, Hao-Wen; Batten, Marcel; Chantrill, Lorraine; Grimmond, Sean M.; Gill, Anthony J.; Samra, Jaswinder; Evans, Thomas R. Jeffry; Sasaki, Takako; Phan, Tri G.; Swarbrick, Alexander; Sansom, Owen J.; Morton, Jennifer P.; Pajic, Marina; Parker, Benjamin L.; Herrmann, David; Cox, Thomas R.; Timpson, Paul
A MXI1-NUTM1 fusion protein with MYC-like activity suggests a novel oncogenic mechanism in a subset ofNUTM1-rearranged tumors

一种具有MYC样活性的MXI1-NUTM1融合蛋白在一个肿瘤亚群ofNUTM1-rearranged一种新的致癌机制

LABORATORY INVESTIGATION
IF4.2
2021-01-0114
OAAI
McEvoy, Christopher R.; Holliday, Holly; Thio, Niko; Mitchell, Catherine; Choong, David Y.; Yellapu, Bhargavi; Leong, Hui San; Xu, Huiling; Lade, Stephen; Browning, Judy; Takano, Elena A.; Byrne, David J.; Gill, Anthony J.; Duong, Cuong P.; Li, Jason; Fellowes, Andrew P.; Fox, Stephen B.; Swarbrick, Alexander; Prall, Owen W. J.
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer

人类三阴性乳腺癌中与免疫逃避相关的基质细胞多样性

EMBO JOURNAL
IF8.3
2020-08-13260
OAAI
Wu, Sunny Z.; Roden, Daniel L.; Wang, Chenfei; Holliday, Holly; Harvey, Kate; Cazet, Aurelie S.; Murphy, Kendelle J.; Pereira, Brooke; Al-Eryani, Ghamdan; Bartonicek, Nenad; Hou, Rui; Torpy, James R.; Junankar, Simon; Chan, Chia-Ling; Lam, Chuan En; Hui, Mun N.; Gluch, Laurence; Beith, Jane; Parker, Andrew; Robbins, Elizabeth; Segara, Davendra; Mak, Cindy; Cooper, Caroline; Warrier, Sanjay; Forrest, Alistair; Powell, Joseph; O'Toole, Sandra; Cox, Thomas R.; Timpson, Paul; Lim, Elgene; Liu, X. Shirley; Swarbrick, Alexander
Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

基底细胞样乳腺癌分化抑制因子4 (ID4) 的蛋白质组学分析

BREAST CANCER RESEARCH
IF5.6
2020-06-117
OAAI
Baker, Laura A.; Holliday, Holly; Roden, Daniel; Krisp, Christoph; Wu, Sunny Z.; Junankar, Simon; Serandour, Aurelien A.; Mohammed, Hisham; Nair, Radhika; Sankaranarayanan, Geetha; Law, Andrew M. K.; McFarland, Andrea; Simpson, Peter T.; Lakhani, Sunil; Dodson, Eoin; Selinger, Christina; Anderson, Lyndal; Samimi, Goli; Hacker, Neville F.; Lim, Elgene; Ormandy, Christopher J.; Naylor, Matthew J.; Simpson, Kaylene; Nikolic, Iva; OToole, Sandra; Kaplan, Warren; Cowley, Mark J.; Carroll, Jason S.; Molloy, Mark; Swarbrick, Alexander

研究方向

暂未获取到该数据
D
David S. Ziegler
H 指数:45论文数:632被引数:8,555
M
Maria Tsoli
H 指数:27论文数:249被引数:3,621
A
Alexander Swarbrick
H 指数:55论文数:402被引数:1.1万
C
Chelsea Mayoh
H 指数:33论文数:324被引数:3,989
S
Samuel E. Ross
H 指数:9论文数:25被引数:376
B
Benjamin S. Rayner
H 指数:23论文数:91被引数:1,581
A
Anjana Gopalakrishnan
H 指数:7论文数:66被引数:270
A
Anahid Ehteda
H 指数:17论文数:85被引数:978
A
Aaminah Khan
H 指数:7论文数:48被引数:409
N
Nisitha Jayatilleke
H 指数:6论文数:41被引数:263