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M

Matthew S. Waitkus

Duke University School of Medicine
H指数:19
被引数:1,558

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SMARCAL1 is a targetable synthetic lethal therapeutic vulnerability in ATRX-deficient gliomas that use alternative lengthening of telomeres

SMARCAL1是ATRX缺陷型胶质瘤中一种可靶向的合成致死治疗弱点，该胶质瘤使用端粒替代性延长机制

Neuro-Oncology
IF13.4
2026-02-010
PRE
Brown, Alexandrea; Strickland, Laura M.; Erman, Elise N.; Pirozzi, Christopher J.; Low, Justin T.; Diplas, Bill H.; Gibson, Emiley; Shobande, Mariah; Khambati, Taher; Krylova, Marharyta; Liu, Heng; Mclendon, Roger E.; Reitman, Zachary J.; Keir, Stephen T.; Zou, Lee; Ashley, David M.; Waitkus, Matthew S.
Multi-omic spatial analysis of the tumor microenvironment in gliomas
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Klymyshyn, Dmytro; Jain, Vaibhav; Whaley, Lauren; Hocke, Emily; Ben Cheikh, Bassem; Smith, Alan; Abramson, Karen; Nelson, Nadine; Satterfield, Diane; Thomas, Elizabeth; Lopez, Giselle; Hariharan, Seetha; Brown, Michael; Jhaveri, Niyati; McLendon, Roger; Ashley, David; Waitkus, Matthew; Gregory, Simon
Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas
NATURE COMMUNICATIONS
IF15.7
2024-01-256
OAAI
Hariharan, Seethalakshmi; Whitfield, Benjamin T.; Pirozzi, Christopher J.; Waitkus, Matthew S.; Brown, Michael C.; Bowie, Michelle L.; Irvin, David M.; Roso, Kristen; Fuller, Rebecca; Hostettler, Janell; Dharmaiah, Sharvari; Gibson, Emiley A.; Briley, Aaron; Mangoli, Avani; Fraley, Casey; Shobande, Mariah; Stevenson, Kevin; Zhang, Gao; Malgulwar, Prit Benny; Roberts, Hannah; Roskoski, Martin; Spasojevic, Ivan; Keir, Stephen T.; He, Yiping; Castro, Maria G.; Huse, Jason T.; Ashley, David M.
Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells

癌症相关的SMARCAL1功能丧失突变促进端粒酶阴性胶质母细胞瘤细胞中端粒的替代延长和肿瘤发生

NEURO-ONCOLOGY
IF13.4
2023-01-237
OA
Liu, Heng; Xu, Cheng; Diplas, Bill H.; Brown, Alexandrea; Strickland, Laura M.; Yao, Haipei; Ling, Jinjie; McLendon, Roger E.; Keir, Stephen T.; Ashley, David M.; He, Yiping; Waitkus, Matthew S.
The integrated genomic and epigenomic landscape of brainstem glioma
NATURE COMMUNICATIONS
IF15.7
2020-06-1745
OAAI
Chen, Lee H.; Pan, Changcun; Diplas, Bill H.; Xu, Cheng; Hansen, Landon J.; Wu, Yuliang; Chen, Xin; Geng, Yibo; Sun, Tao; Sun, Yu; Zhang, Peng; Wu, Zhen; Zhang, Junting; Li, Deling; Zhang, Yang; Wu, Wenhao; Wang, Yu; Li, Guangyu; Yang, Jie; Wang, Xiaoyue; Xu, Ce; Wang, Sizhen; Waitkus, Matthew S.; He, Yiping; McLendon, Roger E.; Ashley, David M.; Yan, Hai; Zhang, Liwei

研究方向

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B
Bill H. Diplas
H 指数:28论文数:296被引数:4,500
C
Christopher J. Pirozzi
H 指数:19论文数:131被引数:1,987
D
David M. Ashley
H 指数:60论文数:589被引数:1.7万
R
Roger E. McLendon
H 指数:131论文数:735被引数:11.6万
Hai YAN 封面图
Hai YAN
H 指数:56论文数:318被引数:2.6万
L
Lee H. Chen
H 指数:14论文数:80被引数:1,085
Y
Yiping He
H 指数:33论文数:183被引数:9,920
P
Paula K. Greer
H 指数:21论文数:92被引数:2,428
D
Darell D. Bigner
H 指数:147论文数:1,127被引数:15.0万
Z
Zachary J. Reitman
H 指数:28论文数:188被引数:5,826