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Genomics 2 Proteins portal: a resource and discovery tool for linking genetic screening outputs to protein sequences and structures Genomics 2 Proteins portal: 用于将遗传筛选输出与蛋白质序列和结构联系起来的资源和发现工具 Kwon, Seulki; Safer, Jordan; Nguyen, Duyen T.; Hoksza, David; May, Patrick; Arbesfeld, Jeremy A.; Rubin, Alan F.; Campbell, Arthur J.; Burgin, Alex; Iqbal, Sumaiya 分享 收藏
Carbapenem-resistant Acinetobacter baumannii complex in the United States-An epidemiological and molecular description of isolates collected through the Emerging Infections Program, 2019 美国耐碳青霉烯类鲍曼不动杆菌复合体-通过新兴感染计划收集的分离株的流行病学和分子描述,2019 Bulens, Sandra N.; Campbell, Davina; McKay, Susannah L.; Vlachos, Nicholas; Burgin, Alex; Burroughs, Mark; Padila, Jasmine; Grass, Julian E.; Jacob, Jesse T.; Smith, Gillian; Muleta, Daniel B.; Maloney, Meghan; Macierowski, Bobbie; Wilson, Lucy E.; Vaeth, Elisabeth; Lynfield, Ruth; O'Malley, Sean; Vagnone, Paula M. Snippes; Dale, Jennifer; Janelle, Sarah J.; Czaja, Christopher A.; Johnson, Helen; Phipps, Erin C.; Flores, Kristina G.; Dumyati, Ghinwa; Tsay, Rebecca; Beldavs, Zintars G.; Cassidy, P. Maureen; Hall, Amanda; Walters, Maroya S.; Guh, Alice Y.; Magill, Shelley S.; Lutgring, Joseph D. 分享 收藏
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer O'Connell, James; Porter, John; Kroeplien, Boris; Norman, Tim; Rapecki, Stephen; Davis, Rachel; McMillan, David; Arakaki, Tracy; Burgin, Alex; Fox, David, III; Ceska, Tom; Lecomte, Fabien; Maloney, Alison; Vugler, Alex; Carrington, Bruce; Cossins, Benjamin P.; Bourne, Tim; Lawson, Alastair 分享 收藏
PDE3A modulation for cancer therapy Wu, Xiaoyun; Lewis, Timothy; de Waal, Luc; Gao, Galen; Zhang, Jian; Schenone, Monica; Garvie, Colin; Diamond, Brett; Lorrey, Selena; Cherniack, Andrew; Corsello, Steven; Burgin, Alex; Golub, Todd; Schreiber, Stuart; Meyerson, Matthew; Greulich, Heidi 分享 收藏
Saturation mutagenesis of KRAS reveals the functional landscape of missense variants Kim, Eejung; Ly, Seav Huong; Persky, Nicole S.; Wang, Belinda; Yang, Xiaoping; Piccioni, Federica; Labella, Katherine; Doshi, Mihir; Lintner, Robert E.; Zhu, Cong; Steelman, Scott; Root, David E.; Johannessen, Cory M.; Burgin, Alex B.; MacConaill, Laura E.; Hahn, William C.; Aguirre, Andrew J. 分享 收藏
Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants Brenan, Lisa; Andreev, Aleksandr; Cohen, Ofir; Pantel, Sasha; Kamburov, Atanas; Cacchiarelli, Davide; Persky, Nicole S.; Zhu, Cong; Bagul, Mukta; Goetz, Eva M.; Burgin, Alex B.; Garraway, Levi A.; Getz, Gad; Mikkelsen, Tarjei S.; Piccioni, Federica; Root, David E.; Johannessen, Cory M. 分享 收藏
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts Guaitoli, Giambattista; Raimondi, Francesco; Gilsbach, Bernd K.; Gomez-Llorente, Yacob; Deyaert, Egon; Renzi, Fabiana; Li, Xianting; Schaffner, Adam; Jagtap, Pravin Kumar Ankush; Boldt, Karsten; von Zweydorf, Felix; Gotthardt, Katja; Lorimer, Donald D.; Yue, Zhenyu; Burgin, Alex; Janjic, Nebojsa; Sattler, Michael; Versees, Wim; Ueffing, Marius; Ubarretxena-Belandia, Iban; Kortholt, Arjan; Gloeckner, Christian Johannes 分享 收藏
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics de Waal, Luc; Lewis, Timothy A.; Rees, Matthew G.; Tsherniak, Aviad; Wu, Xiaoyun; Choi, Peter S.; Gechijian, Lara; Hartigan, Christina; Faloon, Patrick W.; Hickey, Mark J.; Tolliday, Nicola; Carr, Steven A.; Clemons, Paul A.; Munoz, Benito; Wagner, Bridget K.; Shamji, Alykhan F.; Koehler, Angela N.; Schenone, Monica; Burgin, Alex B.; Schreiber, Stuart L.; Greulich, Heidi; Meyerson, Matthew 分享 收藏
Some of the most interesting CASP11 targets through the eyes of their authors Kryshtafovych, Andriy; Moult, John; Basle, Arnaud; Burgin, Alex; Craig, Timothy K.; Edwards, Robert A.; Fass, Deborah; Hartmann, Marcus D.; Korycinski, Mateusz; Lewis, Richard J.; Lorimer, Donald; Lupas, Andrei N.; Newman, Janet; Peat, Thomas S.; Piepenbrink, Kurt H.; Prahlad, Janani; van Raaij, Mark J.; Rohwer, Forest; Segall, Anca M.; Seguritan, Victor; Sundberg, Eric J.; Singh, Abhimanyu K.; Wilson, Mark A.; Schwede, Torsten 分享 收藏
Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th critical assessment of techniques for protein structure prediction experiment CASP10 (vol 82, pg 26, 2014) Kryshtafovych, Andriy; Moult, John; Bales, Patrick; Bazan, J. Fernando; Biasini, Marco; Burgin, Alex; Chen, Chen; Cochran, Frank V.; Craig, Timothy K.; Das, Rhiju; Fass, Deborah; Garcia-Doval, Carmela; Herzberg, Osnat; Lorimer, Donald; Luecke, Hartmut; Ma, Xiaolei; Nelson, Daniel C.; van Raaij, Mark J.; Rohwer, Forest; Segall, Anca; Seguritan, Victor; Zeth, Kornelius; Schwede, Torsten 分享 收藏
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Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10 Kryshtafovych, Andriy; Moult, John; Bales, Patrick; Bazan, J. Fernando; Biasini, Marco; Burgin, Alex; Chen, Chen; Cochran, Frank V.; Craig, Timothy K.; Das, Rhiju; Fass, Deborah; Garcia-Doval, Carmela; Herzberg, Osnat; Lorimer, Donald; Luecke, Hartmut; Ma, Xiaolei; Nelson, Daniel C.; van Raaij, Mark J.; Rohwer, Forest; Segall, Anca; Seguritan, Victor; Zeth, Kornelius; Schwede, Torsten 分享 收藏
Structure and function of a cyanophage-encoded peptide deformylase Frank, Jeremy A.; Lorimer, Don; Youle, Merry; Witte, Pam; Craig, Tim; Abendroth, Jan; Rohwer, Forest; Edwards, Robert A.; Segall, Anca M.; Burgin, Alex B., Jr. 分享 收藏
Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets Davies, Douglas R.; Gelinas, Amy D.; Zhang, Chi; Rohloff, John C.; Carter, Jeffrey D.; O'Connell, Daniel; Waugh, Sheela M.; Wolk, Steven K.; Mayfield, Wesley S.; Burgin, Alex B.; Edwards, Thomas E.; Stewart, Lance J.; Gold, Larry; Janjic, Nebojsa; Jarvis, Thale C. 分享 收藏
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Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety 设计磷酸二酯酶4D (PDE4D) 变构调节剂以增强认知并提高安全性 Burgin, Alex B.; Magnusson, Olafur T.; Singh, Jasbir; Witte, Pam; Staker, Bart L.; Bjornsson, Jon M.; Thorsteinsdottir, Margret; Hrafnsdottir, Sigrun; Hagen, Timothy; Kiselyov, Alex S.; Stewart, Lance J.; Gurney, Mark E. 分享 收藏
Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography Davies, Douglas R.; Mamat, Bjorn; Magnusson, Olafur T.; Christensen, Jeff; Haraldsson, Magnus H.; Mishra, Rama; Pease, Brian; Hansen, Erik; Singh, Jasbir; Zembower, David; Kim, Hidong; Kisclyov, Alex S.; Burgin, Alex B.; Gurney, Mark E.; Stewart, Lance J. 分享 收藏