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A

Alessio Nocentini

istituto di fisiologia clinica (ifc-cnr)

49H指数
324论文数
8.6K被引数
收录论文 214
发表时间
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Structure-Activity Relationship Studies for 1; 3; 4-Thiadiazole-Based Bacterial Carbonic Anhydrase Inhibitors with In Vivo Efficacy against Drug-Resistant Neisseria gonorrhoeae基于1,3,4-噻二唑的抗菌碳酸酐酶抑制剂的结构-活性关系研究及其对耐药性奈瑟氏淋病奈瑟菌的体内疗效
errJournal of Medicinal Chemistry
IF6.8
err2026-05-06
err0
PREAI
errPrabhakara R. Tharra; Molly S. Youse; Nader S. Abutaleb; Abdallah S. Abdelsattar; Katrina J. Holly; Alessio Nocentini; Ahmed A. Abouelkhair; Carolyn K. Metcalfe; Chao-Jan Liao; Venkatesh P. Thriumalaikumar; Farman Ali; Anil Kumar Marapaka; Faith L. Drummond; Olivia C. Snell; Claudiu T. Supuran; Mohamed N. Seleem; Daniel P. Flaherty
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Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity双-三唑连接的苯磺酰胺的设计与合成：作为具有化疗增敏活性的选择性碳酸酐酶IX/XII抑制剂
errJournal of Medicinal Chemistry
IF6.8
err2026-04-30
err0
PREAI
errEslam Roshdy; Ahmet Kilic; Muhamad Mustafa; Ismail Celik; Zeynep Betül Sarı; Ender Simsek; Alessio Nocentini; Simone Giovannuzzi; Claudiu T. Supuran; Özen Özensoy Güler; Jean-Yves Winum; Manabu Abe
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Discovery of a Mixed and Prodrug-Like Inhibition Mechanism for Phosphocoumarins and Phosphoquinolinones against Human Carbonic Anhydrases发现磷香豆素和磷喹啉酮对人碳酸酐酶的混合型和前药样抑制机制
errJournal of Medicinal Chemistry
IF6.8
err2026-04-29
err0
errOAAI
errAlessio Nocentini; Simone Giovannuzzi; Vincenzo Alterio; Alessandro Bonardi; Rudolfs Barons; Raivis Zalubovskis; Wagdy M. Eldehna; Rossella Aronne; Davide Esposito; Enrico Luchinat; Giuseppina De Simone; Gianluca Bartolucci; Paola Gratteri; Mattia Mori; Claudiu T. Supuran
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A New Series of Amino Alcohol Oxime Ethers as Activators of Human Brain Carbonic Anhydrases: Advances in Selective Activation of Human Carbonic Anhydrase VII新型氨基醇肟醚作为人脑碳酸酐酶的激活剂：在人碳酸酐酶VII选择性激活方面的进展
errChemMedChem
IF3.4
err2026-04-28
err0
PREAI
errMangini, Camilla; Di Leo, Riccardo; Castagnoli, Jacopo; Nocentini, Alessio; Gratteri, Paola; Taliani, Sabrina; Supuran, Claudiu T.; Rossello, Armando; Cuffaro, Doretta; Nuti, Elisa
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Coumarin–Thiourea Hybrids: Structural Features Governing CA Inhibition and Antiproliferative Effects香豆素-硫脲杂化物：调控碳酸酐酶抑制和抗增殖效应的结构特征
errInternational Journal of Molecular Sciences
IF4.9
err2026-04-23
err0
errOAAI
errAlma Fuentes-Aguilar; Rebecca Colombo; Aday González-Bakker; Adrián Puerta; Penélope Merino-Montiel; Sara Montiel-Smith; José L. Vega-Báez; Simone Giovannuzzi; Alessio Nocentini; José G. Fernández-Bolaños; Claudiu T. Supuran; José M. Padrón; Óscar López
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Benzoxaboroles Are Inhibitors of the η-Class Carbonic Anhydrase From Plasmodium falciparum苯并硼氮杂环是恶性疟原虫η类碳酸酐酶的抑制剂
errArchiv der Pharmazie
IF3.6
err2026-02-08
err0
errOAAI
errAlessandro Bonardi; Sharon Wein; Muhamad Mustafa; Rachel Cerdan; Viviana de Luca; Clemente Capasso; Paola Gratteri; Claudiu T. Supuran; Alessio Nocentini; Jean-Yves Winum
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First-in-Class Dual PDGFR/Carbonic Anhydrase IX/XII Inhibitors: 6; 7-Dimethoxyquinoline-Sulfonamides as Promising Antileukemic Agents一流的双重PDGFR/碳酸酐酶IX/XII抑制剂: 6; 7-二甲氧基喹啉-磺酰胺作为有前途的抗白血病药
errJournal of Medicinal Chemistry
IF6.8
err2026-01-26
err0
errOAAI
errEslam Roshdy; Eva Řezníčková; Mostafa M. Elbadawi; Ismail Celik; Simone Giovannuzzi; Denisa Veselá; Veronika Vojáčková; Petra Krňávková; Alessio Nocentini; Claudiu T. Supuran; Vladimír Kryštof; Wagdy M. Eldehna; Manabu Abe
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Targeting Metabolic and pH Regulatory Pathways in Cancer via Dual Inhibition of Nicotinamide Phosphoribosyltransferase and Carbonic Anhydrases IX and XII
errJournal of Medicinal Chemistry
IF6.8
err2026-01-19
err0
PREAI
errNiccolò Paoletti; Simone Giovannuzzi; Massimiliano Gasparrini; Andrea Ammara; Zaroon Zaroon; Nadia Raffaelli; Filomena De Nigris; Paola Gratteri; Claudiu T. Supuran; Alessio Nocentini
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Discovery of Enaminone-Linked Benzofuran Derivatives as Dual VEGFR-2/hCA IX Inhibitors Exhibiting Hypoxia-Mediated Chemosensitization作为具有缺氧介导的化学增敏作用的二重VEGFR-2/hCA IX抑制剂的Enaminone连接的苯并呋喃衍生物的发现
errRSC Med. Chem.
IF0
err2025-12-18
err0
PREAI
errWagdy M. Eldehna; Zainab Elsayed; Mohamed Elnagar; Andrea Ammara; Mahmoud S Elkotamy; Rehan Monir; Alessio Nocentini; Mohammad M. Al-Sanea; Claudiu Supuran; Haytham O. Tawfik; Hatem A. Abdel-Aziz; Ahmed T. Negmeldin
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Bacterial Carbonic Anhydrase Inhibitor CAI0019 Demonstrates Efficacy in Enterococcus faecium Septicemic Peritonitis Mouse Model While Sparing the Microbiome细菌碳酸酐酶抑制剂CAI0019在屎肠球菌败血症性腹膜炎小鼠模型中显示出疗效，同时保护了肠道菌群
errACS Infectious Diseases
IF3.8
err2025-12-11
err0
PREAI
errNader S. Abutaleb; Katrina J. Holly; Carolyn K. Metcalfe; Ahmed A. Abouelkhair; Prabhakara R. Tharra; Annadka Shrinidhi; Abdallah S. Abdelsattar; Victoria Burgo; Glory Melotte; Tomi Akin-Olabiyi; Sean Knoblauch; Ramanujam Ramaswamy; Che Woodson; Venkatesh P. Thirumalaikumar; J. Alejandra Rodriguez; Franklin J. Yeo; Olivia C. Snell; Alessio Nocentini; Anitha Sundararajan; Matthew R. Olson; Claudiu T. Supuran; Mohamed N. Seleem; Daniel P. Flaherty
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Identification of isatin-triazole-benzenesulfonamide hybrids as dual hCA IX/XII and c-met inhibitors with hypoxia-mediated chemo-sensitizing activity鉴定异噁唑-三唑-苯磺酰胺类杂合物作为具有缺氧介导化疗增敏活性的双重hCA IX/XII和c-met抑制剂
errBioorganic Chemistry
IF4.7
err2025-10-06
err0
PREAI
errWagdy M. Eldehna; Mohamed R. Elnagar; Simone Giovannuzzi; Amr Tayel; Maha-Hamadien Abdulla; Noura S. Alhassan; Moataz A. Shaldam; Alessio Nocentini; Claudiu T. Supuran; Haytham O. Tawfik
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2-(Piperidin-1-yl)-N-(4-sulfamoylphenyl)acetamide derivatives as novel inhibitors of cancer-associated carbonic anhydrase isoforms IX and XII2-(哌啶-1-基)-N-(4-磺酰胺苯基)乙酰胺衍生物作为新型癌症相关碳酸酐酶同工酶IX和XII的抑制剂
errInternational Journal of Biological Macromolecules
IF8.5
err2025-08-11
err0
PREAI
errWagdy M. Eldehna; Mostafa M. Elbadawi; Zainab M. Elsayed; Simone Giovannuzzi; Mahmoud S. Elkotamy; Ahmed E. Elsawi; Saleh A. Ahmed; Mahmoud Rashed; Alessio Nocentini; Claudiu T. Supuran; Hatem A. Abdel-Aziz
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Design; Synthesis; and In Vitro Anticancer Evaluation of Thiazole-Based Chalcones Linked to Sulfanilamide as Tumor-Associated Carbonic Anhydrase IX and XII Inhibitors设计；合成；及体外抗癌评价的基于噻唑的查尔酮连接磺胺作为肿瘤相关碳酸酐酶IX和XII抑制剂
errJournal of Medicinal Chemistry
IF6.8
err2025-07-07
err0
PREAI
errAli M. Elshamsy; Muhamad Mustafa; Alessio Nocentini; Maria Luisa Massardi; Taha F. S. Ali; Safwat M. Rabea; Burak Tüzün; Michael Smietana; Serkan Kapancık; Mohamed Abdel-Aziz; Roberto Ronca; Claudiu T. Supuran; Jean-Yves Winum; Hamada Hashem
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Selective Inhibition of Carbonic Anhydrase IX and XII by Natural Coumarin Coladonin and Its Derivatives: Promising Antimelanoma and Antiglioblastoma Agents天然香豆素Coladonin及其衍生物对碳酸酐酶IX和XII的选择性抑制：极具潜力的抗黑色素瘤和抗胶质母细胞瘤药物
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2025-05-19
err0
PREAI
errMustafa, M; Baccari, W; Nocentini, A; Massardi, ML; Smietana, M; Abbass, EM; Saidi, I; Znati, M; Ben Jannet, H; Ronca, R; Supuran, CT; Winum, JY
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Unraveling the Potential of Amino-, Acylamino-, and Ureido-Substituted 3H-1,2-Benzoxaphosphepine 2-Oxides toward Nanomolar Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII揭示氨基、酰胺氨基和脲基取代的3H-1,2-苯并恶磷杂庚英烷2-氧化物作为肿瘤相关碳酸酐酶IX和XII纳摩尔抑制剂的潜力
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2025-05-13
err0
PREAI
errBalasova, A; Pustenko, A; Angeli, A; Andreucci, E; Biagioni, A; Nocentini, A; Carta, F; Supuran, CT; Zalubovskis, R
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Exploration of Aromatic Hydrazides as Inhibitors of Human Carbonic Anhydrases芳香酰肼作为人碳酸酐酶抑制剂的探索
errARCHIV DER PHARMAZIE
IF3.6
err2025-04-01
err0
errOAAI
errMenendez, German Benito; Giovannuzzi, Simone; Bonardi, Alessandro; Nocentini, Alessio; Gratteri, Paola; Supuran, Claudiu T.
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Tetrazole Is a Novel Zinc Binder Chemotype for Carbonic Anhydrase Inhibition
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-12-25
err0
PREAI
errGiovannuzzi, Simone; Angeli, Andrea; Begines, Paloma; Ferraroni, Marta; Nocentini, Alessio; Supuran, Claudiu T.
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Development of novel organometallic sulfonamides with N-ethyl or N-methyl benzenesulfonamide units as potential human carbonic anhydrase I, II, IX and XII isoforms' inhibitors: Synthesis, biological evaluation and docking studies
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2024-11-01
err0
PREAI
errGallardo, Miguel; Arancibia, Rodrigo; Supuran, Claudiu T.; Nocentini, Alessio; Villaman, David; Toro, Patricia M.; Munoz-Osses, Michelle; Mascayano, Carolina
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Discovery of new sulfonamide-tethered 2-aryl-4-anilinoquinazolines as the first-in-class dual carbonic anhydrase and EGFR inhibitors
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2024-11-01
err2
PREAI
errEldehna, Wagdy M.; Elsayed, Zainab M.; Ammara, Andrea; Hassab, Mahmoud A. El; Almahli, Hadia; Fares, Mohamed; Nocentini, Alessio; Supuran, Claudiu T.; Abou-Seri, Sahar M.
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Superacid-Synthesized Fluorinated Diamines Act as Selective hCA IV Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-10-24
err0
PREAI
errBerrino, Emanuela; Michelet, Bastien; Vitse, Kassandra; Nocentini, Alessio; Bartolucci, Gianluca; Martin-Mingot, Agnes; Gratteri, Paola; Carta, Fabrizio; Supuran, Claudiu T.; Thibaudeau, Sebastien
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