James T. Coates - Publications, H-index & Citations

James T. Coates

university of oxford

13H指数

68论文数

649被引数

收录论文 21

发表时间

Structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors to modify tumour hypoxia 基于结构的优化芬氟拉明衍生的氧化磷酸化抑制剂以修饰肿瘤缺氧

rsc med. chem.

IF0

2026-04-29

OAAI

James P. Holt-Martyn †; Nicole Machado †; James T. T. Coates; Rathi Puliyadi; Thomas Ashton; Elysia Traynor; Samina Aslam; Thomas K. Wise; Gonzalo Rodriguez-Berriguete; Christopher J. Schofield; Geoff S. Higgins

Antibody-Drug Conjugate Sacituzumab Govitecan Enables a Sequential TOP1/PARP Inhibitor Therapy Strategy in Patients with Breast Cancer 抗体药物偶联物Sacituzumab Govitecan可在乳腺癌患者中实现序贯TOP1/PARP抑制剂治疗策略

CLINICAL CANCER RESEARCH

IF10.2

2024-05-06

OAAI

Bardia, Aditya; Sun, Sheng; Thimmiah, Nayana; Coates, James T.; Wu, Bogang; Abelman, Rachel O.; Spring, Laura; Moy, Beverly; Ryan, Phoebe; Melkonyan, Mark N.; Partridge, Ann; Juric, Dejan; Peppercorn, Jeffrey; Parsons, Heather; Wander, Seth A.; Attaya, Victoria; Lormil, Brenda; Shellock, Maria; Nagayama, Aiko; Bossuyt, Veerle; Isakoff, Steven J.; Tolaney, Sara M.; Ellisen, Leif W.

Systematic identification of pathways associated with antibody drug conjugate sensitivity in breast cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Wu, Bogang; Sun, Sheng; Thimmiah, Nayana; Nagayama, Aiko; Coates, James T.; Liu, Ting; Thant, Win; Bitman, Elena; Li, David; Doench, John; Bardia, Aditya; Ellisen, Leif W.

Intratumoral heterogeneity drives resistance to Antibody Drug Conjugate therapy: Analysis of the NeoSTAR trial of neoadjuvant Sacituzumab govitecan for localized TNBC

CANCER RESEARCH

IF16.6

2024-02-01

PREAI

Spring, Laura M.; Wu, Bogang; Liu, Ting; Geisberg, Jacob; Cristea, Simona; Bossuyt, Veerle; Abelman, Rachel Occhiogrosso; Peiris, Nicole; Coates, James; Koh, Siang-Boon; Zhang, Mengran; Ryan, Lianne; Moy, Beverly; Isakoff, Steven J.; Tolaney, Sara M.; Michor, Franziska; Bardia, Aditya; Ellisen, Leif W.

Utilizing scRNA sequencing to understand biomarkers of response and resistance to Sacitizumab Govetican in localized TNBC

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Peiris, Nicole; Cristea, Simona; Zhang, Mengran; Koh, Siang; Coates, James; Smidt, Ilze; Bossuyt, Veerle; Spring, Laura; Bardia, Aditya; Ellisen, Leif

Systematic identification of pathways associated with antibody drug conjugate sensitivity in breast cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Wu, Bogang; Sun, Sheng; Thimmiah, Nayana; Nagayama, Aiko; Coates, James; Thant, Win; Li, David; Doench, John; Bardia, Aditya; Ellisen, Leif

Machine learning-driven critical care decision making

JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

IF7.1

2022-04-07

OAAI

Coates, James T.; de Koning, Christiaan

Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer 抗原和有效负载靶标的平行基因组改变介导三阴性乳腺癌中对Sacituzumab Govitecan的多克隆获得的临床耐药性

CANCER DISCOVERY

IF33.3

2021-08-17

OAAI

Coates, James T.; Sun, Sheng; Leshchiner, Ignaty; Thimmiah, Nayana; Martin, Elizabeth E.; McLoughlin, Daniel; Danysh, Brian P.; Slowik, Kara; Jacobs, Raquel A.; Rhrissorrakrai, Kahn; Utro, Filippo; Levovitz, Chaya; Denault, Elyssa; Walmsley, Charlotte S.; Kambadakone, Avinash; Stone, James R.; Isakoff, Steven J.; Parida, Laxmi; Juric, Dejan; Getz, Gad; Bardia, Aditya; Ellisen, Leif W.

The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress

CELL DEATH DISCOVERY

IF7

2020-10-27

OAAI

Coates, James T. T.; Rodriguez-Berriguete, Gonzalo; Puliyadi, Rathi; Ashton, Thomas; Prevo, Remko; Wing, Archie; Granata, Giovanna; Pirovano, Giacomo; McKenna, Gillies W.; Higgins, Geoff S.

Genomics models in radiotherapy: From mechanistic to machine learning

MEDICAL PHYSICS

IF3.2

2020-05-17

OAAI

Kang, John; Coates, James T.; Strawderman, Robert L.; Rosenstein, Barry S.; Kerns, Sarah L.

Unified Radiogenomic Prediction of Late Radiotherapy Toxicities

RADIOTHERAPY AND ONCOLOGY

IF5.3

2019-04-01

OAAI

Coates, J.; Jeyaseelan, A.; Ybarra, N.; Tao, J.; David, M.; Faria, S.; Souhami, L.; Cury, F.; Duclos, M.; El Naqa, I.

Tumor pH and Protein Concentration Contribute to the Signal of Amide Proton Transfer Magnetic Resonance Imaging 肿瘤pH和蛋白浓度对酰胺质子转移磁共振成像信号的贡献

CANCER RESEARCH

IF16.6

2019-04-01

OAAI

Ray, Kevin J.; Simard, Manon A.; Larkin, James R.; Coates, James; Kinchesh, Paul; Smart, Sean C.; Higgins, Geoff S.; Chappell, Michael A.; Sibson, Nicola R.

Radiogenomics and radiotherapy response modeling 放射基因组学与放射治疗反应建模

PHYSICS IN MEDICINE AND BIOLOGY

IF3.4

2017-08-01

OAAI

El Naqa, Issam; Kerns, Sarah L.; Coates, James; Luo, Yi; Speers, Corey; West, Catharine M. L.; Rosenstein, Barry S.; Ten Haken, Randall K.

Big Data Analytics for Prostate Radiotherapy 前列腺放射治疗的大数据分析

FRONTIERS IN ONCOLOGY

IF3.3

2016-06-14

OAAI

Coates, James; Souhami, Luis; El Naqa, Issam

Outcome modeling techniques for prostate cancer radiotherapy: Data, models, and validation

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS

IF2.7

2016-03-01

PREAI

Coates, James; El Naqa, Issam

Data Driven Radiogenomic Modeling of Radiation Induced Toxicities in Prostate Cancer

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2015-11-01

OAAI

Coates, J.; Jeyaseelan, K.; Ybarra, N.; David, M.; Faria, S.; Souhami, L.; Cury, F.; El Naqa, I.

Contrasting analytical and data-driven frameworks for radiogenomic modeling of normal tissue toxicities in prostate cancer

RADIOTHERAPY AND ONCOLOGY

IF5.3

2015-04-01

PREAI

Coates, James; Jeyaseelan, Asha K.; Ybarra, Norma; David, Marc; Faria, Sergio; Souhami, Luis; Cury, Fabio; Duclos, Marie; El Naga, Issam

Radiogenomic Modeling of Normal Tissue Toxicities in Prostate Cancer Patients Receiving Hypofractionated Radiotherapy

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2014-09-01

OAAI

Coates, J.; Jeyaseelan, K.; Ybarra, N.; Marc, D.; Sergio, E.; Souhami, L.; Cury, F.; Duclos, M.; El Naqa, I.

BEST IN PHYSICS (THERAPY) - Radiogenomic Modeling of Normal Tissue Toxicities in Prostate Cancer Patients Receiving Hypofractionated Radiotherapy

MEDICAL PHYSICS

IF3.2

2014-05-29

PREAI

Coates, J.; Jeyaseelan, K.; Ybarra, N.; David, M.; Faria, S.; Souhami, L.; Cury, F.; Duclos, M.; El Naqa, I.

Local chemotherapeutic agents for the treatment of ocular malignancies

SURVEY OF OPHTHALMOLOGY

IF5.9

2014-01-01

PREAI

Fernandes, Bruno F.; Nikolitch, Katerina; Coates, James; Novais, Gustavo; Odashiro, Alexandre; Odashiro, Patricia P.; Belfort, Rubens N.; Burnier, Miguel N., Jr.

研究方向