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Thomas A. Hilimire

University of Rochester

14H指数
20论文数
702被引数
收录论文 15
发表时间
CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivoCDK8/19抑制在体外和体内预防CDK4/6抑制剂的适应性耐药
err2026-08-19
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errZachary T. Mack; Margarita Yastrebova; Chang-uk Lim; Xiaokai Ding; Jing Li; Alvina Khamidullina; Amanda C. Sharko; Michael Saint-Antoine; Thomas A. Hilimire; Gary P. Schools; Kaitlyn Digsby; Amanda Eckstrom; Erin Belcher; Gwenael Madiot; Hao Ji; Vitali Sikirzhitski; Chao Cai; Guoshuai Cai; Abhyudai Singh; Victor Tatarskiy
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Mediator kinase inhibitors suppress triple- negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors介质激酶抑制剂通过mTOR和AKT抑制剂抑制三阴性乳腺癌的生长并延长肿瘤抑制
err2024-11-14
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errDing, Xiaokai; Liang, Jiaxin; Sharko, Amanda C.; Hilimire, Thomas A.; Li, Jing; Loskutov, Jurgen; Mack, Zachary T.; Ji, Hao; Schools, Gary P.; Cai, Chao; Pugacheva, Elena N.; Chen, Mengqian; Roninson, Igor B.; Broude, Eugenia V.
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Mediator kinase inhibition reverses castration resistance of advanced cancer
err2024-03-28
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errLi, Jing; Hilimire, Thomas A.; Liu, Yueying; Wang, Lili; Liang, Jiaxin; Gyorffy, Balazs; Sikirzhytski, Vitali; Ji, Hao; Zhang, Li; Cheng, Chen; Ding, Xiaokai; Kerr, Kendall R.; Dowling, Charles E.; Chumanevich, Alexander A.; Mack, Zachary T.; Schools, Gary P.; Lim, Chang-uk; Ellis, Leigh; Zi, Xiaolin; Porter, Donald C.; Broude, Eugenia V.; McInnes, Campbell; Wilding, George; Lilly, Michael B.; Roninson, Igor B.; Chen, Mengqian
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Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies(vol11, e0472822, 2023)
err2024-03-05
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errPiepenbrink, Michael; Oladunni, Fatai; Nogales, Aitor; Khalil, Ahmed M.; Fitzgerald, Theresa; Hilimire, Thomas A.; Basu, Madhubanti; Fucile, Christopher; Topham, David J.; Rosenberg, Alexander F.; Martinez-Sobrido, Luis; Kobie, James J.
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Machine Learning Informs RNA-Binding Chemical Space
err2023-02-06
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errYazdani, Kamyar; Jordan, Deondre; Yang, Mo; Fullenkamp, Christopher R.; Calabrese, David R.; Boer, Robert; Hilimire, Thomas; Allen, Timothy E. H.; Khan, Rabia T.; Schneekloth Jr, John S.
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Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites
err2021-01-01
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errZhao, Xue Zhi; Kiselev, Evgeny; Lountos, George T.; Wang, Wenjie; Tropea, Joseph E.; Needle, Danielle; Hilimire, Thomas A.; Schneekloth, John S., Jr.; Waugh, David S.; Pommier, Yves; Burke, Terrence R., Jr.
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Peptides Derived from the Tight Junction Protein CLDN1 Disrupt the Skin Barrier and Promote Responsiveness to an Epicutaneous Vaccine
err2020-02-01
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errBrewer, Matthew G.; Anderson, Elizabeth A.; Pandya, Radha P.; De Benedetto, Anna; Yoshida, Takeshi; Hilimire, Thomas A.; Martinez-Sobrido, Luis; Beck, Lisa A.; Miller, Benjamin L.
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Increasing the Safety Profile of the Master Donor Live Attenuated Influenza Vaccine
err2020-01-29
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errHilimire, Thomas A.; Nogales, Aitor; Chiem, Kevin; Ortego, Javier; Martinez-Sobrido, Luis
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Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor
err2020-01-01
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errSchmidt, Karyn; Weidmann, Chase A.; Hilimire, Thomas A.; Yee, Elaine; Hatfield, Breanne M.; Schneekloth, John S., Jr.; Weeks, Kevin M.; Novina, Carl D.
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Enhancing the ligand efficiency of anti-HIV compounds targeting frameshift-stimulating RNA
err2019-07-01
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errAnokhina, Viktoriya S.; McAnany, John D.; Ciesla, Jessica H.; Hilimire, Thomas A.; Santoso, Netty; Miao, Hongyu; Miller, Benjamin L.
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Potent Inhibition of Zika Virus Replication by Aurintricarboxylic Acid
err2019-04-12
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errPark, Jun-Gyu; Avila-Perez, Gines; Madere, Ferralita; Hilimire, Thomas A.; Nogales, Aitor; Almazan, Fernando; Martinez-Sobrido, Luis
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Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex
err2018-10-12
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errCalabrese, David R.; Chen, Xiang; Leon, Elena C.; Gaikwad, Snehal M.; Phyo, Zaw; Hewitt, William M.; Alden, Stephanie; Hilimire, Thomas A.; He, Fahu; Michalowski, Aleksandra M.; Simmons, John K.; Saunders, Lindsey B.; Zhang, Shuling; Connors, Daniel; Walters, Kylie J.; Mock, Beverly A.; Schneekloth, John S., Jr.
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HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells
err2017-04-27
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errHilimire, Thomas A.; Chamberlain, Jeffrey M.; Anokhina, Viktoriya; Bennett, Ryan P.; Swart, Oliver; Myers, Jason R.; Ashton, John M.; Stewart, Ryan A.; Featherston, Aaron L.; Gates, Kathleen; Helms, Eric D.; Smith, Harold C.; Dewhurst, Stephen; Miller, Benjamin L.
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N-Methylation as a Strategy for Enhancing the Affinity and Selectivity of RNA-binding Peptides: Application to the HIV-1 Frameshift-Stimulating RNA
err2015-11-03
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errHilimire, Thomas A.; Bennett, Ryan P.; Stewart, Ryan A.; Garcia-Miranda, Pablo; Blume, Alex; Becker, Jordan; Sherer, Nathan; Helms, Eric D.; Butcher, Samuel E.; Smith, Harold C.; Miller, Benjamin L.
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High-Affinity Recognition of HIV-1 Frameshift-Stimulating RNA Alters Frameshifting in Vitro and Interferes with HIV-1 Infectivity
err2014-01-15
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errOfori, Leslie O.; Hilimire, Thomas A.; Bennett, Ryan P.; Brown, Nathaniel W., Jr.; Smith, Harold C.; Miller, Benjamin L.
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