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P

Patrick Rabe

University of Oxford
H指数:32
被引数:2,974

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Unanticipated intermediates during isopenicillin N synthase catalysis identified by time-resolved X-ray free-electron laser studies

异噁唑霉素N合成酶催化过程中通过时间分辨X射线自由电子激光研究鉴定出的非预期中间体

Nature Catalysis
IF44.6
2026-10-090
OAAI
Patrick Rabe; Hiroki Makita; Rebecca Southwart; Midhun George Thomas; Mihails Kazaks; Shyam Basak; Tiankun Zhou; William K. Myers; Margaret D. Doyle; Philipp S. Simon; Shusaku Hayama; J. Frederick W. Mosselmans; Alexander T. Stead; Abraham O. Oluwole; Malkit Sami; Ian Clifton; Pierre Aller; Asmit Bhowmick; Anthony Tumber; Jos J. A. G. Kamps; Karina Calvopiña; Agata Butryn; Robert Bosman; Arjun Cheema; Jordan Welsh; James D. S. Linyard; Frederick J. H. Foster; Pauline A. Lang; Mariska de Munnik; Stephen M. Keable; Medhanjali Dasgupta; In-Sik Kim; Isabel Bogacz; Kuntal Chatterjee; Kyle D. Sutherlin; Corey J. Kaminsky; Jürgen Brem; Michael A. McDonough; Christina Redfield; James R. D. Montgomery; Coral Mycroft; Anastasya Shilova; Nicholas Devenish; Frederic P. Poitevin; Sebastian Dehe; Vandana Tiwari; Humberto Sanchez; Daniel J. Rosenberg; Mark S. Hunter; Leland B. Gee; Uwe Bergmann; Roberto Alonso-Mori; Jaehyun Park; Shigeki Owada; Kensuke Tono; Danny Axford; Robin L. Owen; Daniel W. Paley; Nicholas K. Sauter; David Mittan-Moreau; Aaron S. Brewster; Carol V. Robinson; Vittal K. Yachandra; Junko Yano; Edgars Suna; Christo Z. Christov; Allen M. Orville; Jan F. Kern; Christopher J. Schofield
KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9

KDM3A催化组蛋白H3K9上的乙酰基-赖氨酸氧化为羟基乙酰基-赖氨酸

Nature Chemistry
IF20.2
2026-04-150
OAAI
Roman Belle; John-Paul Bukowski; Rachel Schiller; Ronald Cutler; Eidarus Salah; Robert S. Dawber; Anthony Tumber; Joanna Bonnici; Jessica D. Kindrick; Loane Serrano; Patrick Rabe; Catrine Johansson; Marie-Hélène Ruchaud; Richard J. Hopkinson; William D. Figg, Sr; Paul E. Brennan; David R. Mole; Simone Sidoli; Akane Kawamura; Christopher J. Schofield
Structural basis of the promiscuity of the unusual Fe(II) and 2-oxoglutarate dependent human aspartate/asparagine-β-hydroxylase

非常规Fe(II)和2-氧戊二酸依赖性人天冬氨酸/天冬酰胺-β-羟化酶的底物不专一性的结构基础

Nature Communications
IF15.7
2026-02-250
OAAI
Mariska de Munnik; Amelia Brasnett; Tiankun Zhou; William Myers; Yicheng Wang; Kuntal Chatterjee; Anthony Tumber; Stephen A. Marshall; Philipp S. Simon; Pierre Aller; Anastasiia Shilova; Danny Axford; Hiroki Makita; Daniel W. Paley; Vandana Tiwari; Alexander T. Stead; Sebastian Dehe; Humberto Sanchez; Daniel J. Rosenberg; Roberto Alonso-Mori; Asmit Bhowmick; Junko Yano; Vittal K. Yachandra; Jaehyun Park; Sehan Park; Allen M. Orville; Lennart Brewitz; Jan F. Kern; Christopher J. Schofield; Patrick Rabe
Filamin C dimerisation is regulated by HSPB7

Filamin C二聚化由HSPB7调控。

NATURE COMMUNICATIONS
IF15.7
2025-05-010
OA
Wang, Zihao; Cao, Guodong; Collier, Miranda P.; Qiu, Xingyu; Broadway-Stringer, Sophie; Saman, Dominik; Ng, Jediael Z. Y.; Sen, Navoneel; Azad, Amar J.; Hooper, Charlotte; Zimmermann, Johannes; Mcdonough, Michael A.; Brem, Juergen; Rabe, Patrick; Song, Haigang; Alderson, T. Reid; Schofield, Christopher J.; Bolla, Jani R.; Djinovic-Carugo, Kristina; Fuerst, Dieter O.; Warscheid, Bettina; Degiacomi, Matteo T.; Allison, Timothy M.; Hochberg, Georg K. A.; Robinson, Carol V.; Gehmlich, Katja; Benesch, Justin L. P.
X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis
SCIENCE ADVANCES
IF12.5
2021-08-2034
OAAI
Rabe, Patrick; Kamps, Jos J. A. G.; Sutherlin, Kyle D.; Linyard, James D. S.; Aller, Pierre; Pham, Cindy C.; Makita, Hiroki; Clifton, Ian; McDonough, Michael A.; Leissing, Thomas M.; Shutin, Denis; Lang, Pauline A.; Butryn, Agata; Brem, Jurgen; Gul, Sheraz; Fuller, Franklin D.; Kim, In-Sik; Cheah, Mun Hon; Fransson, Thomas; Bhowmick, Asmit; Young, Iris D.; O'Riordan, Lee; Brewster, Aaron S.; Pettinati, Ilaria; Doyle, Margaret; Joti, Yasumasa; Owada, Shigeki; Tono, Kensuke; Batyuk, Alexander; Hunter, Mark S.; Alonso-Mori, Roberto; Bergmann, Uwe; Owen, Robin L.; Sauter, Nicholas K.; Claridge, Timothy D. W.; Robinson, Carol V.; Yachandra, Vittal K.; Yano, Junko; Kern, Jan F.; Orville, Allen M.; Schofield, Christopher J.
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
NATURE COMMUNICATIONS
IF15.7
2021-07-2241
OAAI
Butryn, Agata; Simon, Philipp S.; Aller, Pierre; Hinchliffe, Philip; Massad, Ramzi N.; Leen, Gabriel; Tooke, Catherine L.; Bogacz, Isabel; Kim, In-Sik; Bhowmick, Asmit; Brewster, Aaron S.; Devenish, Nicholas E.; Brem, Jurgen; Kamps, Jos J. A. G.; Lang, Pauline A.; Rabe, Patrick; Axford, Danny; Beale, John H.; Davy, Bradley; Ebrahim, Ali; Orlans, Julien; Storm, Selina L. S.; Zhou, Tiankun; Owada, Shigeki; Tanaka, Rie; Tono, Kensuke; Evans, Gwyndaf; Owen, Robin L.; Houle, Frances A.; Sauter, Nicholas K.; Schofield, Christopher J.; Spencer, James; Yachandra, Vittal K.; Yano, Junko; Kern, Jan F.; Orville, Allen M.

研究方向

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C
Christopher J. Schofield
H 指数:112论文数:1,313被引数:6.2万
J
Jeroen S. Dickschat
H 指数:62论文数:383被引数:1.4万
J
Jürgen Brem
H 指数:35论文数:148被引数:3,725
K
Karina Calvopiña
H 指数:15论文数:35被引数:693
J
Jan Rinkel
H 指数:27论文数:65被引数:2,353
A
Allen M. Orville
H 指数:39论文数:194被引数:5,524
P
Pauline A. Lang
H 指数:14论文数:34被引数:812
P
Pierre Aller
H 指数:22论文数:99被引数:2,568
T
Tobias G. Köllner
H 指数:61论文数:192被引数:1.2万
A
Anthony Tumber
H 指数:41论文数:206被引数:7,482