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H

Hao Zhang

weill cornell medicine
H指数:21
被引数:1,555

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Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome
CELL CHEMICAL BIOLOGY
IF7.2
2023-05-0113
OAAI
Deni, Ioanna; Stokes, Barbara H.; Ward, Kurt E.; Fairhurst, Kate J.; Pasaje, Charisse Flerida A.; Yeo, Tomas; Akbar, Shirin; Park, Heekuk; Muir, Ryan; Bick, Daniella S.; Zhan, Wenhu; Zhang, Hao; Liu, Yi Jing; Ng, Caroline L.; Kirkman, Laura A.; Almaliti, Jehad; Gould, Alexandra E.; Duffey, Maelle; O'Donoghue, Anthony J.; Uhlemann, Anne-Catrin; Niles, Jacquin C.; da Fonseca, Paula C. A.; Gerwick, William H.; Lin, Gang; Bogyo, Matthew; Fidock, David A.
Dual-pharmacophore artezomibs hijack the Plasmodium eubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance
CELL CHEMICAL BIOLOGY
IF7.2
2023-05-016
OAAI
Zhan, Wenhu; Li, Daqiang; Subramanyaswamy, Shubha Bevkal; Liu, Yi Jing; Yang, Changmei; Zhang, Hao; Harris, Jacob C.; Wang, Rong; Zhu, Songbiao; Rocha, Hedy; Sherman, Julian; Qin, Junling; Herring, Mikayla; Simwela, Nelson V.; Waters, Andrew P.; Sukenick, George; Cui, Liwang; Rodriguez, Ana; Deng, Haiteng; Nathan, Carl F.; Kirkman, Laura A.; Lin, Gang
Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors-Part II
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-01-113
PRE
Zhang, Hao; Ginn, John; Zhan, Wenhu; Leung, Annie; Liu, Yi J.; Toita, Akinori; Okamoto, Rei; Wong, Tzu-Tshin; Imaeda, Toshihiro; Hara, Ryoma; Michino, Mayako; Yukawa, Takafumi; Chelebieva, Sevil; Tumwebaze, Patrick K.; Vendome, Jeremie; Beuming, Thijs; Sato, Kenjiro; Aso, Kazuyoshi; Rosenthal, Philip J.; Cooper, Roland A.; Liverton, Nigel; Foley, Michael; Meinke, Peter T.; Nathan, Carl F.; Kirkman, Laura A.; Lin, Gang
Mayako Michino-Jeremie Vendome
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-06-2111
OA
Zhang, Hao; Ginn, John; Zhan, Wenhu; Liu, Yi J.; Leung, Annie; Toita, Akinori; Okamoto, Rei; Wong, Tzu-Tshin; Imaeda, Toshihiro; Hara, Ryoma; Yukawa, Takafumi; Michino, Mayako; Vendome, Jeremie; Beuming, Thijs; Sato, Kenjiro; Aso, Kazuyoshi; Meinke, Peter T.; Nathan, Carl F.; Kirkman, Laura A.; Lin, Gang
Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-05-0510
OAAI
Zhang, Hao; Hsu, Hao-Chi; Kahne, Shoshanna C.; Hara, Ryoma; Zhan, Wenhu; Jiang, Xiuju; Burns-Huang, Kristin; Ouellette, Tierra; Imaeda, Toshihiro; Okamoto, Rei; Kawasaki, Masanori; Michino, Mayako; Wong, Tzu-Tshin; Toita, Akinori; Yukawa, Takafumi; Moraca, Francesca; Vendome, Jeremie; Saha, Priya; Sato, Kenjiro; Aso, Kazuyoshi; Ginn, John; Meinke, Peter T.; Foley, Michael; Nathan, Carl F.; Darwin, K. Heran; Li, Huilin; Lin, Gang
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice

在人源化小鼠中开发具有抗疟疾活性的高选择性恶性疟原虫蛋白酶体抑制剂

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2021-03-1122
OAAI
Zhan, Wenhu; Zhang, Hao; Ginn, John; Leung, Annie; Liu, Yi J.; Michino, Mayako; Toita, Akinori; Okamoto, Rei; Wong, Tzu-Tshin; Imaeda, Toshihiro; Hara, Ryoma; Yukawa, Takafumi; Chelebieva, Sevil; Tumwebaze, Patrick K.; Lafuente-Monasterio, Maria Jose; Martinez-Martinez, Maria Santos; Vendome, Jeremie; Beuming, Thijs; Sato, Kenjiro; Aso, Kazuyoshi; Rosenthal, Philip J.; Cooper, Roland A.; Meinke, Peter T.; Nathan, Carl F.; Kirkman, Laura A.; Lin, Gang

研究方向

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G
Gang Lin
H 指数:27论文数:88被引数:2,530
W
Wenhu Zhan
H 指数:17论文数:65被引数:711
L
Laura A. Kirkman
H 指数:22论文数:60被引数:2,136
P
Peter T. Meinke
H 指数:40论文数:207被引数:6,274
C
Carl Nathan
H 指数:127论文数:426被引数:9.0万
J
John D. Ginn
H 指数:17论文数:61被引数:750
T
Tzu‐Tshin Wong
H 指数:8论文数:23被引数:188
T
Takafumi Yukawa
H 指数:10论文数:20被引数:318
厍
厍学功
H 指数:38论文数:303被引数:4,858
谢
谢新刚
H 指数:30论文数:186被引数:2,400