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S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling 反应性糖酵解代谢物对KEAP1的S-乳酰修饰激活NRF2信号传导 Ko, Yeonjin; Hong, Mannkyu; Lee, Seungbeom; Kumar, Manoj; Ibrahim, Lara; Nutsch, Kayla; Stanton, Caroline; Sandoval, Braddock; Sondermann, Phillip; Bulos, Maya L.; Iaconelli, Jonathan; Chatterjee, Arnab K.; Wiseman, R. Luke; Schultz, Peter G.; Bollong, Michael J. 分享 收藏
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Allosteric Inhibition of the Tumor-Promoting Interaction Between Exon 2-Depleted Splice Variant of Aminoacyl-Transfer RNA Synthetase-Interacting Multifunctional Protein 2 and Heat Shock Protein 70(S) Kim, Dae Gyu; Huddar, Srigouri; Lim, Semi; Kong, Jiwon; Lee, Yuno; Park, Chul Min; Lee, Seungbeom; Suh, Young-Ger; Kim, Minkyoung; Lee, Kyeong; Lee, Sunkyung; Kim, Sunghoon 分享 收藏
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Discovery of novel potent migrastatic Thiazolo[5,4-b]pyridines targeting Lysyl-tRNA synthetase (KRS) for treatment of Cancer metastasis Lee, Seungbeom; Kwon, Nam Hoon; Seo, Bokyung; Lee, Jin Young; Cho, Hye Young; Kim, Kyeojin; Kim, Hyun Su; Jung, Kiwon; Jeon, Young Ho; Kim, Sunghoon; Suh, Young-Ger 分享 收藏
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ERRγ ligand HPB2 upregulates BDNF-TrkB and enhances dopaminergic neuronal phenotype Err γ 配体HPB2上调bdnf-trkb并增强多巴胺能神经元表型 Kim, Hyo In; Lee, Seungbeom; Lim, Juhee; Chung, Sungkyun; Koo, Tae-Sung; Ji, Yu-Geun; Suh, Young-Ger; Son, Woo Sung; Kim, Seok-Ho; Choi, Hyun Jin 分享 收藏
Collective Syntheses of Guaiane Sesquiterpenes: Stereoselective Syntheses of (+)-Dysodensiol F, (+)-10β,14-Dihydroxy-allo-aromadendrane, and (-)-Dendroside C Aglycon Kim, Hyun Su; Park, Hyunkyung; Lim, Juhee; Lim, Changjin; Kim, Taewoo; Lee, Seungbeom; Hur, Joonseong; Sim, Jaehoon; Choi, Hyun Jin; Suh, Young-Ger 分享 收藏
An Electrophilic Deguelin Analogue Inhibits STAT3 Signaling in H-Ras-Transformed Human Mammary Epithelial Cells: The Cysteine 259 Residue as a Potential Target 亲电子的Deguelin类似物抑制h-ras转化的人乳腺上皮细胞中的STAT3信号传导: 半胱氨酸259残基是潜在的靶标 Hong, Sung-Jun; Kim, Jin-Tae; Kim, Su-Jung; Cho, Nam-Chul; Kim, Kyeojin; Lee, Seungbeom; Suh, Young-Ger; Cho, Kyung-Cho; Kim, Kwang Pyo; Surh, Young-Joon 分享 收藏
A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction 一种新型小分子STAT3抑制剂SLSI-1216通过诱导凋亡抑制三阴性乳腺癌细胞的增殖和肿瘤生长 Park, Soo Kyung; Byun, Woong Sub; Lee, Seungbeom; Han, Young Taek; Jeong, Yoo-Seong; Jang, Kyungkuk; Chung, Suk-Jae; Lee, Jeeyeon; Suh, Young-Ger; Lee, Sang Kook 分享 收藏
Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy Sivaraman, Aneesh; Kim, Dae Gyu; Bhattarai, Deepak; Kim, Minkyoung; Lee, Hwa Young; Lim, Semi; Kong, Jiwon; Goo, Ja-Il; Shim, Seunghwan; Lee, Seungbeom; Suh, Young-Ger; Choi, Yongseok; Kim, Sunghoon; Lee, Kyeong 分享 收藏
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15-Keto prostaglandin E2 suppresses STAT3 signaling and inhibits breast cancer cell growth and progression Lee, Eun Ji; Kim, Su-Jung; Hahn, Young-Il; Yoon, Hyo-Jin; Han, Bitnara; Kim, Kyeojin; Lee, Seungbeom; Kim, Kwang Pyo; Suh, Young Ger; Na, Hye-Kyung; Surh, Young-Joon 分享 收藏
Investigation of B, C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents Kim, Ho Shin; Van-Hai Hoang; Hong, Mannkyu; Kim, Kyung Chul; Ann, Jihyae; Cong-Truong Nguyen; Seo, Ji Hae; Choi, Hoon; Kim, Jun Yong; Kim, Kyu-Won; Byun, Woong Sub; Lee, Sangkook; Lee, Seungbeom; Suh, Young-Ger; Chen, Jie; Park, Hyun-Ju; Cho, Tae-Min; Kim, Ji Young; Seo, Jae Hong; Lee, Jeewoo 分享 收藏
Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy An, Hongchan; Lee, Seungbeom; Lee, Jung Mm; Jo, Dong Hyun; Kim, Joohwan; Jeong, Yoo-Seong; Heo, Mi Jeong; Cho, Chang Sik; Choi, Hoon; Seo, Ji Hae; Hwang, Seyeon; Lim, Jihye; Kim, Taewoo; Jun, Hyoung Oh; Sim, Jaehoon; Lim, Changjin; Hur, Joonseong; Ahn, Jungmin; Kim, Hyun Su; Seo, Seung-Yong; Na, Younghwa; Kim, Seok-Ho; Lee, Jeewoo; Lee, Jeeyeon; Chung, Suk-Jae; Kyu, Young-Myeong; Kim, Kyu-Won; Kim, Sang Geon; Kim, Jeong Hun; Suh, Young-Ger 分享 收藏
Conformation-Enabled Total Syntheses of Ohmyungsamycins A and B and Structural Revision of Ohmyungsamycin B Hur, Joonseong; Jang, Jaebong; Sim, Jaehoon; Son, Woo Sung; Ahn, Hee-Chul; Kim, Tae Sung; Shin, Yern-Hyerk; Lim, Changjin; Lee, Seungbeom; An, Hongchan; Kim, Seok-Ho; Oh, Dong-Chan; Jo, Eun-Kyeong; Jang, Jichan; Lee, Jeeyeon; Suh, Young-Ger 分享 收藏
Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton Ahn, Jungmin; Lim, Changjin; Yun, Hwayoung; Kim, Hyun Su; Kwon, Soonbum; Lee, Jeeyeon; Lee, Seungbeom; An, Hongchan; Park, Hyeong-geun; Suh, Young-Ger 分享 收藏
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