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R

Rolf G. Boot

Leiden University
H指数:57
被引数:1.1万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Unraveling A4GALT Mechanism and Its Modulation With Adamantyl-Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

解析A4GALT机制及其通过金刚烷基-半乳糖基神经酰胺类似物的调控：推进法布里病治疗策略

Angewandte Chemie-International Edition
IF16.9
2026-08-280
OAAI
Nicky de Koster; Òscar Vidal-Gironès; Rowan de Graaf; Ken Kok; Lindsey T. Lelieveld; Jackelien Hoogervorst; Maria J. Ferraz; José Pablo Rivas-Fernández; Rob F. Lammers; Herman S. Overkleeft; Johannes M. F. G. Aerts; Rolf G. Boot; Carme Rovira; Marta Artola
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2020-07-0129
OAAI
Armstrong, Zachary; Kuo, Chi-Lin; Lahav, Danil; Liu, Bing; Johnson, Rachel; Beenakker, Thomas J. M.; de Boer, Casper; Wong, Chung-Sing; van Rijssel, Erwin R.; Debets, Marjoke F.; Florea, Bogdan I.; Hissink, Colin; Boot, Rolf G.; Geurink, Paul P.; Ovaa, Huib; van der Stelt, Mario; van der Marel, Gijsbert M.; Codee, Jeroen D. C.; Aerts, Johannes M. F. G.; Wu, Liang; Overkleeft, Herman S.; Davies, Gideon J.
The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

亚氨基糖amp-dnm通过GLP1改善饱腹感并激活棕色脂肪组织

DIABETES
IF7.5
2019-10-024
OAAI
Herrera Moro Chao, Daniela; Wang, Yanan; Foppen, Ewout; Ottenhoff, Roelof; Van Roomen, Cindy; Parlevliet, Edwin T.; Van Eijk, Marco; Verhoek, Marri; Boot, Rolf; Marques, Andre R.; Scheij, Saskia; Mirzaian, Mina; Kooijman, Sander; Jansen, Kirstin; Wang, Dawei; Mergen, Clarita; Seeley, Randy J.; Tschoep, Matthias H.; Overkleeft, Herman; Rensen, Patrick C. N.; Kalsbeek, Andries; Aerts, Johannes M. F. G.; Yi, Chun-Xia
A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2017-09-2954
OAAI
Lahav, Daniel; Liu, Bing; van den Berg, Richard J. B. H. N.; van den Nieuwendijk, Adrianus M. C. H.; Wennekes, Tom; Ghisaidoobe, Amar T.; Breen, Imogen; Ferraz, Maria J.; Kuo, Chi-Lin; Wu, Liang; Geurink, Paul P.; Ovaa, Huib; van der Marel, Gijsbert A.; van der Stelt, Mario; Boot, Rolf G.; Davies, Gideon J.; Aerts, Johannes M. F. G.; Overkleeft, Herman S.
Stabilization of Glucocerebrosidase by Active Site Occupancy
ACS CHEMICAL BIOLOGY
IF3.8
2017-05-2221
OAAI
Bdira, Fredj Ben; Kallemeijn, Wouter W.; Oussoren, Saskia V.; Scheij, Saskia; Bleijlevens, Boris; Florea, Bogdan I.; van Roomen, Cindy P. A. A.; Ottenhoff, Roelof; van Kooten, Marielle J. F. M.; Walvoort, Marthe T. C.; Witte, Martin D.; Boot, Rolf G.; Ubbink, Marcellus; Overkleeft, Herman S.; Aerts, Johannes M. F. G.

研究方向

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J
Johannes M. F. G. Aerts
H 指数:94论文数:610被引数:2.8万
H
Herman S. Overkleeft
H 指数:83论文数:928被引数:2.8万
M
Marco van Eijk
H 指数:38论文数:78被引数:5,004
R
Roelof Ottenhoff
H 指数:39论文数:94被引数:4,962
S
Saskia Scheij
H 指数:25论文数:43被引数:1,714
M
Marri Verhoek
H 指数:21论文数:46被引数:2,257
W
Wouter W. Kallemeijn
H 指数:29论文数:67被引数:2,511
C
Carla E. M. Hollak
H 指数:78论文数:435被引数:1.9万
B
Bogdan I. Florea
H 指数:48论文数:255被引数:7,408
M
Marta Artola
H 指数:25论文数:75被引数:1,885