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R

Robert N. Pike

La Trobe University

63H指数
279论文数
1.3W被引数
收录论文 102
发表时间
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The crystal structure of the toxin EspC from enteropathogenic Escherichia coli reveals the mechanism that governs host cell entry and cytotoxicity致肠毒素EspC的晶体结构来自肠致病性大肠杆菌，揭示了调控宿主细胞进入和细胞毒性的机制。
errGUT MICROBES
IF11
err2025-03-31
err1
errOAAI
errAkila U. Pilapitiya; Lilian Hor; Jing Pan; Lakshmi C. Wijeyewickrema; Robert N. Pike; Denisse L. Leyton; Jason J Paxman; Begoña Heras
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Molecular Interactions Required for Activation of Complement Component C2 Include Exosites Located on the Serine Protease Domain of C1s and Mannose-Binding Lectin Associated Protease-2
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-02-19
err1
PREAI
errHor, Lilian; Pan, Jing; Pike, Robert N.; Wijeyewickrema, Lakshmi C.
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Effect of a protease-activated receptor-2 antagonist (GB88) on inflammation-related loss of alveolar bone in periodontal disease
errJOURNAL OF PERIODONTAL RESEARCH
IF3.4
err2023-03-31
err1
errOAAI
errFrancis, Nidhish; Sanaei, Reza; Ayodele, Babatunde A.; O'Brien-Simpson, Neil M.; Fairlie, David P.; Wijeyewickrema, Lakshmi C.; Pike, Robert N.; Mackie, Eleanor Jean; Pagel, Charles Neil
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Mapping the binding site of C1-inhibitor for polyanion cofactors绘制C1-inhibitor对聚阴离子辅因子的结合位点
errMOLECULAR IMMUNOLOGY
IF3
err2020-10-01
err5
PREAI
errHor, Lilian; Pan, Jing; Whisstock, James C.; Pike, Robert N.; Wijeyewickrema, Lakshmi C.
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Determination of the crystal structure and substrate specificity of ananain
errBIOCHIMIE
IF3
err2019-11-01
err9
PREAI
errTang Yongqing; Wilmann, Pascal G.; Pan, Jing; West, Michael L.; Brown, Tracey J.; Mynott, Tracey; Pike, Robert N.; Wijeyewickrema, Lakshmi C.
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Protease-associated import systems are widespread in Gram-negative bacteria
errPLOS GENETICS
IF3.7
err2019-10-15
err17
errOAAI
errGrinter, Rhys; Leung, Pok Man; Wijeyewickrema, Lakshmi C.; Littler, Dene; Beckham, Simone; Pike, Robert N.; Walker, Daniel; Greening, Chris; Lithgow, Trevor
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Mapping the cofactor binding site for polyanions of the serpin, C1-inhibitor
errMOLECULAR IMMUNOLOGY
IF3
err2018-10-01
err0
PREAI
errHor, Lilian; Pan, Jing; Pannu, Raj; Pike, Robert N.; Wijeyewickrema, Lakshmi C.
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Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods蛋白酶特异性底物和切割位点预测的生物信息学研究二十年: 对现有方法的全面回顾和基准测试
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2018-08-29
err67
errOAAI
errLi, Fuyi; Wang, Yanan; Li, Chen; Marquez-Lago, Tatiana T.; Leier, Andre; Rawlings, Neil D.; Haffari, Gholamreza; Revote, Jerico; Akutsu, Tatsuya; Chou, Kuo-Chen; Purcell, Anthony W.; Pike, Robert N.; Webb, Geoffrey, I; Smith, A. Ian; Lithgow, Trevor; Daly, Roger J.; Whisstock, James C.; Song, Jiangning
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Molecular basis for the folding of β-helical autotransporter passenger domains
errNATURE COMMUNICATIONS
IF15.7
err2018-04-11
err18
errOAAI
errYuan, Xiaojun; Johnson, Matthew D.; Zhang, Jing; Lo, Alvin W.; Schembri, Mark A.; Wijeyewickrema, Lakshmi C.; Pike, Robert N.; Huysmans, Gerard H. M.; Henderson, Ian R.; Leyton, Denisse L.
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Simultaneous flow cytometric immunophenotyping of necroptosis, apoptosis and RIP1-dependent apoptosis程序性坏死、凋亡和RIP1-dependent凋亡的流式细胞术免疫分型
errMETHODS
IF4.3
err2018-02-01
err23
PREAI
errLee, H. L.; Pike, R.; Chong, M. H. A.; Vossenkamper, A.; Warnes, G.
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The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech
errJOURNAL OF IMMUNOLOGY
IF3.4
err2017-12-01
err15
errOAAI
errPang, Siew Siew; Wijeyewickrema, Lakshmi C.; Hor, Lilian; Tan, Sheareen; Lameignere, Emilie; Conway, Edward M.; Blom, Anna M.; Mohlin, Frida C.; Liu, Xuyu; Payne, Richard J.; Whisstock, James C.; Pike, Robert N.
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A T cell-specific knockout reveals an important role for protease-activated receptor 2 in lymphocyte development
errINTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
IF2.8
err2017-11-01
err4
PREAI
errFrancis, Nidhish; Every, Alison L.; Ayodele, Babatunde A.; Pike, Robert N.; Mackie, Eleanor J.; Pagel, Charles N.
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Recruitment of Human C1 Esterase Inhibitor Controls Complement Activation on Blood Stage Plasmodium falciparum Merozoites招募人类C1酯酶抑制剂控制血液阶段恶性疟原虫裂殖子的补体激活
errJOURNAL OF IMMUNOLOGY
IF3.4
err2017-06-15
err25
errOAAI
errKennedy, Alexander T.; Wijeyewickrema, Lakshmi C.; Huglo, Alisee; Lin, Clara; Pike, Robert; Cowman, Alan F.; Tham, Wai-Hong
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Protein unfolding is essential for cleavage within the α-helix of a model protein substrate by the serine protease, thrombin
errBIOCHIMIE
IF3
err2016-03-01
err8
PREAI
errRobertson, Amy L.; Headey, Stephen J.; Ng, Natasha M.; Wijeyewickrema, Lakshmi C.; Scanlon, Martin J.; Pike, Robert N.; Bottomley, Stephen P.
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Structural basis for substrate specificity of Helicobacter pylori M17 aminopeptidase
errBIOCHIMIE
IF3
err2016-02-01
err21
PREAI
errModak, Joyanta K.; Rut, Wioletta; Wijeyewickrema, Lakshmi C.; Pike, Robert N.; Drag, Marcin; Roujeinikova, Anna
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The protease cathepsin L regulates Th17 cell differentiation
errJOURNAL OF AUTOIMMUNITY
IF7
err2015-12-01
err46
errOAAI
errHou, Lifei; Cooley, Jessica; Swanson, Richard; Poh Chee Ong; Pike, Robert N.; Bogyo, Matthew; Olson, Steven T.; Remold-O'Donnell, Eileen
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Investigation of the mechanism of interaction between Mannose-binding lectin-associated serine protease-2 and complement C4
errMOLECULAR IMMUNOLOGY
IF3
err2015-10-01
err13
PREAI
errDrentin, Nicole; Conroy, Paul; Gunzburg, Menachem J.; Pike, Robert N.; Wijeyewickrema, Lakshmi C.
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The role of tne Lys628 (192) residue of the complement protease, C1s, in interacting with peptide and protein substrates
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2014-09-17
err3
errOAAI
errWijeyewickrema, Lakshmi Carmel; Duncan, Renee Charlene; Pike, Robert Neil
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Scabies Mite Inactive Serine Proteases Are Potent Inhibitors of the Human Complement Lectin Pathway
errPLOS NEGLECTED TROPICAL DISEASES
IF3.4
err2014-05-22
err44
errOAAI
errReynolds, Simone L.; Pike, Robert N.; Mika, Angela; Blom, Anna M.; Hofmann, Andreas; Wijeyewickrema, Lakshmi C.; Kemp, Dave; Fischer, Katja
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Total Synthesis of Homogeneous Variants of Hirudin P6: A PostTranslationally Modified Anti- Thrombotic Leech- Derived Protein
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2014-03-11
err36
PREAI
errHsieh, Yves S. Y.; Wijeyewickrema, Lakshmi C.; Wilkinson, Brendan L.; Pike, Robert N.; Payne, Richard J.
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研究方向

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合作期刊
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Kuo‐Chen Chou
H 指数: 124 · 论文数: 483
B
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J
Jamie Rossjohn
H 指数: 118 · 论文数: 985
A
Alan F. Cowman
H 指数: 113 · 论文数: 462
T
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H 指数: 108 · 论文数: 640
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