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J

James C. Whisstock

monash university
H指数:78
被引数:2.1万

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Helicobacter pylori induces the production of interleukin-37 to promote broad immunosuppression and enhance colonization

幽门螺杆菌（Helicobacter pylori）诱导白细胞介素-37（interleukin-37）的产生，以促进广泛的免疫抑制并增强定植。

Gut Microbes
IF11
2026-02-140
OA
Rishi Pathirana; Nagaja Capitani; Christopher McCrory; Chiara Della Bella; Isabella Stuart; William Gilmore; Natalie J. Bitto; Michelle D. Tate; Ella L. Johnston; Lauren Zavan; Steven Batinovic; John Pedersen; Sam Norden; Hassan Chaudhry; Richard L. Ferrero; Tony M. Korman; David Greening; Neil O’Brien-Simpson; Andrew M. Ellisdon; James C. Whisstock; Steve Petrovski; Renea A. Taylor; Mario M. D’Elios; Claudia A. Nold-Petry; Marcel F. Nold; Maria Kaparakis-Liaskos
Fragment-based and structure-guided discovery of perforin inhibitors
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2023-12-011
OAAI
Jose, Jiney; Law, Ruby H. P.; Leung, Eleanor W. W.; Wai, Dorothy C. C.; Akhlaghi, Hedieh; Chandrashekaran, Indu R.; Caradoc-Davies, Tom T.; Voskoboinik, Ilia; Feutrill, John; Middlemiss, David; Jeevarajah, Devadharshini; Bashtannyk-Puhalovich, Tanya; Giddens, Anna C.; Lee, Tet Woo; Jamieson, Stephen M. F.; Trapani, Joseph A.; Whisstock, James C.; Spicer, Julie A.; Norton, Raymond S.
The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9

补体C5b-9膜攻击复合物的新表位是由邻近的C9辅助区域形成的

COMMUNICATIONS BIOLOGY
IF5.1
2023-01-133
OAAI
Bayly-Jones, Charles; Ho, Bill H. T.; Lau, Corinna; Leung, Eleanor W. W.; D'Andrea, Laura; Lupton, Christopher J. J.; Ekkel, Susan M. M.; Venugopal, Hariprasad; Whisstock, James C. C.; Mollnes, Tom E. E.; Spicer, Bradley A. A.; Dunstone, Michelle A. A.
Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation

Mpeg1对于抗菌或抗病毒免疫不是必需的，但与抗原呈递有关。

IMMUNOLOGY AND CELL BIOLOGY
IF3
2022-05-126
OA
Ebrahimnezhaddarzi, Salimeh; Bird, Catherina H.; Allison, Cody C.; Tuipulotu, Daniel E.; Kostoulias, Xenia; Macri, Christophe; Stutz, Michael D.; Abraham, Gilu; Kaiserman, Dion; Pang, Siew Siew; Man, Si Ming; Mintern, Justine D.; Naderer, Thomas; Peleg, Anton Y.; Pellegrini, Marc; Whisstock, James C.; Bird, Phillip, I
Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential
CELL CHEMICAL BIOLOGY
IF7.2
2022-04-018
OAAI
Bujotzek, Alexander; Tiefenthaler, Georg; Lariviere, Laurent; D'Andrea, Laura; Marquez, Elsa A.; Rudloff, Ina; Cho, Steven X.; Deen, Nadia S.; Richter, Wolfgang; Regenass-Lechner, Franziska; Poehler, Alexander; Whisstock, James C.; Sydow-Andersen, Jasmin; Reiser, Xaver; Schuster, Sabine; Neubauer, Jeannette; Hoepfl, Sebastian; Richter, Kirsten; Nold, Marcel F.; Nold-Petry, Claudia A.; Schumacher, Felix; Ellisdon, Andrew M.
Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities

坏死性小肠结肠炎的病理免疫学表征揭示了新的治疗机会

NATURE COMMUNICATIONS
IF15.7
2020-11-1364
OAAI
Cho, Steven X.; Rudloff, Ina; Lao, Jason C.; Pang, Merrin A.; Goldberg, Rimma; Bui, Christine B.; McLean, Catriona A.; Stock, Magdalena; Klassert, Tilman E.; Slevogt, Hortense; Mangan, Niamh E.; Cheng, Wei; Fischer, Doris; Gfroerer, Stefan; Sandhu, Manjeet K.; Ngo, Devi; Bujotzek, Alexander; Lariviere, Laurent; Schumacher, Felix; Tiefenthaler, Georg; Beker, Friederike; Collins, Clare; Kamlin, C. Omar F.; Konig, Kai; Malhotra, Atul; Tan, Kenneth; Theda, Christiane; Veldman, Alex; Ellisdon, Andrew M.; Whisstock, James C.; Berger, Philip J.; Nold-Petry, Claudia A.; Nold, Marcel F.

研究方向

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H 指数:56论文数:233被引数:1.1万
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Ashley M. Buckle
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Joseph A. Trapani
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Andrew M. Ellisdon
H 指数:26论文数:57被引数:2,443