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Tomohiko Ohwada

university of tokyo

45H指数
335论文数
6.3K被引数
收录论文 123
发表时间
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Search for Inhibitors against Inflammatory Responses of Microglia in a Meroterpenoid Library Constructed by Synthetic-Biological Manipulation of Biosynthetic Pathways通过合成-生物法操纵生物合成途径构建的倍半萜类化合物库中筛选抑制小胶质细胞炎症反应的抑制剂
errACS Omega
IF4.3
err2026-03-01
err0
errOAAI
errTakahashi, Kanako; Quan, Zhiyang; Shigemoto-Mogami, Yukari; Zhang, Bei-bei; Ohwada, Tomohiko; Abe, Ikuro; Awakawa, Takayoshi; Sato, Kaoru
err分享
err收藏
Afungi-derived cyclic peptide enhances Th9-mediated antitumor immunity by targeting ZAP70 and SREBP1一种真菌来源的环肽通过靶向ZAP70和SREBP1增强Th9介导的抗肿瘤免疫
errJournal of Clinical Investigation
IF13.6
err2026-02-02
err0
PREAI
errZhao, Wenli; Zhou, Yang; Chen, Yuyang; Sun, Yicheng; Tang, Jiaxin; Zhu, Yihan; Ren, Jie; Du, Tianxu; Wang, Handuo; Gao, Yuan; Hu, Yu; Jiang, Ling; Ohwada, Tomohiko; Luo, Qi; Bi, Enguang
err分享
err收藏
N-[3-(4-(2-methoxyphenyl) piperazine-1-yl) propyl]-heteroaromatic carboxamide as selective α1A/1D-adrenoceptor antagonists: SAR study and metabolic stability evaluationN-[3-(4-(2-甲氧基苯基)哌嗪-1-基)丙基]-杂芳基羧酰胺作为选择性α1A/1D-肾上腺素能受体拮抗剂：构效关系研究及代谢稳定性评价
errBioorganic & Medicinal Chemistry Letters
IF2.2
err2025-12-13
err0
PREAI
errRuxia Duan; Linxin Zhou; Ran Chen; Yajian Huang; Dan Wu; Tomohiko Ohwada; Wei Yi; Junjun Huang
err分享
err收藏
Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrilsGPR34的选择性激动作用可刺激小胶质细胞对淀粉样β纤维的摄取和清除。
errAlzheimer's Research & Therapy
IF7.6
err2025-11-21
err0
errOAAI
errHayato Etani; Sho Takatori; Wenbo Wang; Jumpei Omi; Yusuke Amiya; Aika Akahori; Hirotaka Watanabe; Iki Sonn; Hideyuki Okano; Norikazu Hara; Mai Hasegawa; Akinori Miyashita; Masataka Kikuchi; Takeshi Ikeuchi; Maho Morishima; Yuko Saito; Shigeo Murayama; Takashi Saito; Takaomi C. Saido; Toshiyuki Takai; Tomohiko Ohwada; Junken Aoki; Taisuke Tomita
err分享
err收藏
Benzophenone-Based Phenylogous Peptide Linkage via Friedel–Crafts Acylation基于二苯甲酮的苯并类似肽键连接通过弗里德–克雷夫茨酰化反应
errOrganic Letters
IF5
err2025-10-18
err0
PREAI
errHao Wu; Yuko Otani; Ying Zhou; Bastien Michelet; Sebastien Thibaudeau; Tomohiko Ohwada; Luying Chen
err分享
err收藏
Identifying Bioactive Conformations of Flexible Polyunsaturated Fatty Acids for Ligand-Based Drug Design识别柔性多不饱和脂肪酸的活性构象，用于基于配体的药物设计
errCHEMICAL & PHARMACEUTICAL BULLETIN
IF1.3
err2025-10-01
err0
errOAAI
errChen, Luying; Wu, Mian; Ohwada, Tomohiko
err分享
err收藏
Autocrine/paracrine lysophosphatidylserine signaling suppresses B cell aggregation and tertiary lymphoid structure formation自分泌/旁分泌溶血磷脂酰丝氨酸信号抑制B细胞聚集和三级淋巴结构形成
errISCIENCE
IF4.1
err2025-05-01
err0
errOAAI
errUwamizu, Akiharu; Shinjo, Yuji; Omi, Jumpei; Tatstumi, Manae; Kano, Kuniyuki; Makide, Kumiko; Kitamura, Hajime; Okudaira, Michiyo; Satoh, Keita; Fukami, Fumiya; Kawano, Tasuku; Miyasaka, Tomomitsu; Takahashi, Tomoko; Nakajima, Osamu; Ohwada, Tomohiko; Inoue, Asuka; Aoki, Junken
err分享
err收藏
Switching Conjugation Is the Predominant Factor Contributing to Complete Reversal of Amide cis-trans (Z-E) Preference through N-Methylation
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2025-04-01
err0
PREAI
errHuang, Junjun; Chen, Luying; Ikeda, Hirotaka; Hyodo, Tadashi; Tang, Yulan; Otani, Yuko; Yamaguchi, Kentaro; Inagaki, Satoshi; Ohwada, Tomohiko
err分享
err收藏
Generation and Application of All Possible Conformations of Cyclic Tryptophan within and beyond Post-translational Modification
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2024-12-20
err0
PREAI
errKasahara, Akitomo; Yamada, Ryo; Hyodo, Tadashi; Yamaguchi, Kentaro; Otani, Yuko; Sumimoto, Shimpei; Okada, Masahiro; Ohwada, Tomohiko
err分享
err收藏
Synthesis of Stable Hypervalent Bromine(III) Complexes by in Situ Oxidation with Lewis Acids Containing sp-Hybridized Nitrogen
errORGANIC LETTERS
IF5
err2024-11-11
err0
PREAI
errFujino, Tomohiro; Hyodo, Tadashi; Otani, Yuko; Yamaguchi, Kentaro; Ohwada, Tomohiko
err分享
err收藏
Journal of Medicinal Chemistry Collection: Drug Discovery in Japan
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-23
err0
PREAI
errSuzuki, Takayoshi; Kurata, Haruto; Ohwada, Tomohiko; Onodera, Hideyuki
err分享
err收藏
Structural basis for lysophosphatidylserine recognition by GPR34
errNATURE COMMUNICATIONS
IF15.7
err2024-02-07
err3
errOAAI
errIzume, Tamaki; Kawahara, Ryo; Uwamizu, Akiharu; Chen, Luying; Yaginuma, Shun; Omi, Jumpei; Kawana, Hiroki; Hou, Fengjue; Sano, Fumiya K.; Tanaka, Tatsuki; Kobayashi, Kazuhiro; Okamoto, Hiroyuki H.; Kise, Yoshiaki; Ohwada, Tomohiko; Aoki, Junken; Shihoya, Wataru; Nureki, Osamu
err分享
err收藏
An N-ortho-nitrobenzylated benzanilide amino acid enables control of the conformation and membrane permeability of cyclic peptides
errCHEMICAL COMMUNICATIONS
IF4.2
err2024-01-01
err1
PREAI
errOtani, Yuko; Ichinose, Asami; Wang, Xihong; Huang, Zhihan; Kasahara, Akitomo; Ishii, Mayumi; Watanabe, Eri; Kanamitsu, Kayoko; Tai, Kempei; Kusuhara, Hiroyuki; Ueda, Takumi; Takeuchi, Koh; Ohwada, Tomohiko
err分享
err收藏
Complete amide cis-trans switching synchronized with disulfide bond formation and cleavage in a proline-mimicking system
errCHEMICAL COMMUNICATIONS
IF4.2
err2024-01-01
err0
errOAAI
errCheng, Yuhe; Hyodo, Tadashi; Yamaguchi, Kentaro; Ohwada, Tomohiko; Otani, Yuko
err分享
err收藏
Stabilization of sp-Hybridized Nitrogen Cation by Lewis Acid-Base Complex Formation with Intramolecular Iodine
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2023-11-29
err1
errOAAI
errFujino, Tomohiro; Hyodo, Tadashi; Otani, Yuko; Yamaguchi, Kentaro; Ohwada, Tomohiko
err分享
err收藏
Leucine 434 is essential for docosahexaenoic acid-induced augmentation of L-glutamate transporter current (vol 299, 102793, 2023)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-07-01
err0
errOAAI
errTakahashi, Kanako; Chen, Luying; Sayama, Misa; Wu, Mian; Hayashi, Mariko Kato; Irie, Tomohiko; Ohwada, Tomohiko; Sato, Kaoru
err分享
err收藏
Isolation and Reactions of Imidoyl Fluorides Generated from Oxime Using the Diethylaminosulfur Trifluoride/Tetrahydrofuran (DAST-THF) System
errORGANIC LETTERS
IF5
err2023-05-09
err14
PREAI
errLu, Yipu; Kasahara, Akitomo; Hyodo, Tadashi; Ohara, Kazuaki; Yamaguchi, Kentaro; Otani, Yuko; Ohwada, Tomohiko
err分享
err收藏
Leucine 434 is essential for docosahexaenoic acid-induced augmentation of L-glutamate transporter current
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err5
errOAAI
errTakahashi, Kanako; Chen, Luying; Sayama, Misa; Wu, Mian; Hayashi, Mariko Kato; Irie, Tomohiko; Ohwada, Tomohiko; Sato, Kaoru
err分享
err收藏
Friedel-Crafts Acylation of Aminocarboxylic Acids in Strong Bronsted Acid Promoted by Lewis Base P4O10
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2022-11-01
err11
PREAI
errWu, Hao; Sumita, Akinari; Otani, Yuko; Ohwada, Tomohiko
err分享
err收藏
Friedel-Crafts-Type Acylation and Amidation Reactions in Strong Bronsted Acid: Taming Superelectrophiles
errMOLECULES
IF4.6
err2022-09-14
err15
errOAAI
errSumita, Akinari; Ohwada, Tomohiko
err分享
err收藏

研究方向

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合作学者
合作期刊
H
Hideyuki Okano
H 指数: 145 · 论文数: 1.8K
K
Kozo Kaibuchi
H 指数: 135 · 论文数: 690
T
Takaomi C. Saido
H 指数: 112 · 论文数: 820
H
Hiroyuki Arai
H 指数: 110 · 论文数: 783
T
Tetsuo Nagano
H 指数: 104 · 论文数: 703
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