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收藏分享 收藏 分享 收藏 Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitmentUM171的结构模拟与嵌合性癌症突变体共同劫持E3连接酶KBTBD4以招募HDAC1/2
Chen, Zhuoyao; Chi, Gamma; Balo, Timea; Chen, Xiangrong; Montes, Beatriz Ralsi; Clifford, Steven C.; D'Angiolella, Vincenzo; Szabo, Timea; Kiss, Arpad; Novak, Tibor; Herner, Andras; Kotschy, Andras; Bullock, Alex N. 分享 收藏 分享 收藏 Structure-Atropisomer Stability Relationship in Selective MCL-1 InhibitorsSipos, Szabolcs; Balazs, Barbara; Gati, Tamas; Csekei, Marton; Kovaacs, Mihaly; Szlavik, Zoltan; Paczal, Attila; Balint, Balazs; Murray, James B.; Davidson, James; Hubbard, Roderick E.; Le Toumelin-Braizat, Gaetane; Maragno, Ana Leticia; Geneste, Olivier; Stirling, Andras; Kotschy, Andras 分享 收藏 Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open迈向目标2035: EUbOPEN-一个公私合作伙伴关系，以开放和解锁生物学Tredup, Claudia; Ackloo, Suzanne; Beck, Hartmut; Brown, Peter J.; Bullock, Alex N.; Ciulli, Alessio; Dikic, Ivan; Edfeldt, Kristina; Edwards, Aled M.; Elkins, Jonathan M.; Farin, Henner F.; Fon, Edward A.; Gstaiger, Matthias; Guenther, Judith; Gustavsson, Anna-Lena; Haeberle, Sandra; Isigkeit, Laura; Huber, Kilian V. M.; Kotschy, Andras; Kraemer, Oliver; Leach, Andrew R.; Marsden, Brian D.; Matsui, Hisanori; Merk, Daniel; Montel, Florian; Mulder, Monique P. C.; Mueller, Susanne; Owen, Dafydd R.; Proschak, Ewgenij; Roehm, Sandra; Stolz, Alexandra; Sundstroem, Michael; von Delft, Frank; Willson, Timothy M.; Arrowsmith, Cheryl H.; Knapp, Stefan 分享 收藏 Covalent Inhibitors of KEAP1 with Exquisite SelectivityFejes, Imre; Markacz, Piroska; Tatai, Janos; Rudas, Monika; Dunkel, Petra; Gyuris, Mario; Nyerges, Miklos; Provost, Nicolas; Duvivier, Valerie; Delerive, Philippe; Martiny, Virginie; Bristiel, Alexandra; Vidal, Brice; Richardson, William; Rothweiler, Elisabeth M.; Tranberg-Jensen, Jeppe; Manning, Charlotte E.; Sweeney, Melissa N.; Chalk, Rod; Huber, Kilian V. M.; Bullock, Alex N.; Herner, Andras; Seedorf, Klaus; Vinson, Cedric; Weber, Csaba; Kotschy, Andras 分享 收藏 Structure-Guided Discovery of Selective USP7 Inhibitors with In Vivo ActivityVasas, Attila; Ivanschitz, Lisa; Molnar, Balazs; Kiss, Arpad; Baker, Lisa; Fiumana, Andrea; Macias, Alba; Murray, James B.; Sanders, Emma; Whitehead, Neil; Hubbard, Roderick E.; Saunier, Carine; Monceau, Elodie; Girard, Anne Marie; Rousseau, Marion; Chanrion, Maia; Demarles, Didier; Geneste, Olivier; Weber, Csaba; Lewkowicz, Elodie; Kotschy, Andras 分享 收藏 Synthesis and Systematic Investigation of Lepidiline A and Its Gold(I), Silver(I), and Copper(I) Complexes Using In Vitro Cancer Models and Multipotent Stem CellsToth, Szilard; Szlavik, Marton F.; Mandel, Reka; Fekecs, Fanni; Tusnady, Gabor; Vajda, Flora; Varga, Nora; Apati, Agota; Benyei, Attila; Paczal, Attila; Kotschy, Andras; Szakacs, Gergely 分享 收藏 Competing Domino Knoevenagel-Cyclization Sequences with N-ArylcinnamylaminesKajtar, Mihaly; Kiraly, Sandor Balazs; Benyei, Attila; Kiss-Szikszai, Attila; Konya-Abraham, Anita; Zhang, Ning; Horvath, Lilla Borbala; Bosze, Szilvia; Li, Dehai; Kotschy, Andras; Paczal, Attila; Kurtan, Tibor 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 The Effect of Core Replacement on S64315, a Selective MCL-1 Inhibitor, and Its AnaloguesSipos, Szabolcs; Balint, Balazs; Szabo, Zoltan B.; Ondi, Levente; Csekei, Marton; Szlavik, Zoltan; Proszenyak, Agnes; Murray, James B.; Davidson, James; Chen, Ijen; Dokurno, Pawel; Surgenor, Allan E.; Pedder, Christopher; Hubbard, Roderick E.; Maragno, Ana-Leticia; Chanrion, Maia; Colland, Frederic; Geneste, Olivier; Kotschy, Andras 分享 收藏 Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1BWalmsley, David Lee; Murray, James B.; Dokurno, Pawel; Massey, Andrew J.; Benwell, Karen; Fiumana, Andrea; Foloppe, Nicolas; Ray, Stuart; Smith, Julia; Surgenor, Allan E.; Edmonds, Thomas; Demarles, Didier; Burbridge, Mike; Cruzalegui, Francisco; Kotschy, Andras; Hubbard, Roderick E. 分享 收藏 分享 收藏 Structure-Guided Discovery of Potent and Selective DYRK1A InhibitorsWeber, Csaba; Sipos, Melinda; Paczal, Attila; Balint, Balazs; Kun, Vilibald; Foloppe, Nicolas; Dokurno, Pawel; Massey, Andrew J.; Walmsley, David Lee; Hubbard, Roderick E.; Murray, James; Benwell, Karen; Edmonds, Thomas; Demarles, Didier; Bruno, Alain; Burbridge, Mike; Cruzalegui, Francisco; Kotschy, Andras 分享 收藏 分享 收藏 
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