未登录 Clinical testing of drug treatment shortening in patients with TB using PET/CT imaging of lung lesions Malherbe, Stephanus T.; Chen, Ray Y.; Yu, Xiang; Smith, Bronwyn; Liu, Xin; Gao, Jingcai; Diacon, Andreas H.; Dawson, Rodney; Tameris, Michele; Zhu, Hong; Qu, Yahong; Jin, Hongjian; Pan, Shouguo; Dodd, Lori E.; Wang, Jing; Goldfeder, Lisa C.; Cai, Ying; Arora, Kriti; Vincent, Joel; Narunsky, Kim; Serole, Keboile; Goliath, Rene T.; Da Costa, Laylah; Taliep, Arshad; Aziz, Saalikha; Daroowala, Remy; Thienemann, Friedrich; Mukasa, Sandra; Court, Richard; Sossen, Bianca; Ahlers, Petri; Mendelsohn, Simon C.; White, Lisa; Gouel, Aurelie; Lau, Chuen-Yen; Hassan, Samy; Liang, Lili; Duan, Hongfei; Moghaddam, Gita K.; Paripati, Praveen; Lahouar, Saher; Harris, Michael; Wollenberg, Kurt; Jeffrey, Brendan; Tartakovsky, Mike; Rosenthal, Alex; Duvenhage, Michael; Armstrong, Derek T.; Song, Taeksun; Winter, Jill; Gao, Qian; Via, Laura E.; Wilkinson, Robert J.; Walzl, Gerhard; Barry, Clifton E. 分享 收藏
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Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities Boshoff, Helena I. M.; Young, Katherine; Ahn, Yong-Mo; Yadav, Veena D.; Crowley, Brendan M.; Yang, Lihu; Su, Jing; Oh, Sangmi; Arora, Kriti; Andrews, Jenna; Manikkam, Michelle; Sutphin, Michelle; Smith, Anthony J.; Weiner, Danielle M.; Piazza, Michaela K.; Fleegle, Joel D.; Gomez, Felipe; Dayao, Emmannual K.; Prideaux, Brendan; Zimmerman, Matthew; Kaya, Firat; Sarathy, Jansy; Tan, Vee Yang; Via, Laura E.; Tschirret-Guth, Richard; Lenaerts, Anne J.; Robertson, Gregory T.; Dartois, Veronique; Olsen, David B.; Barry III, Clifton E. 分享 收藏
Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates Shallom, Shamira J.; Tettelin, Herve; Chandrasekaran, Prabha; Park, In Kwon; Agrawal, Sonia; Arora, Kriti; Sadzewicz, Lisa; Milestone, Aaron M.; Aitken, Moira L.; Brown-Elliott, Barbara A.; Wallace, Richard J.; Sampaio, Elizabeth P.; Niederweis, Michael; Olivier, Kenneth N.; Holland, Steven M.; Zelazny, Adrian M. 分享 收藏
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Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions 由制药公司和学术机构组成的财团鉴定对结核分枝杆菌具有活性的 β-内酰胺 Gold, Ben; Zhang, Jun; Quezada, Landys Lopez; Roberts, Julia; Ling, Yan; Wood, Madeleine; Shinwari, Wasima; Goullieux, Laurent; Roubert, Christine; Fraisse, Laurent; Bacque, Eric; Lagrange, Sophie; Filoche-Romme, Bruno; Vieth, Michal; Hipskind, Philip A.; Jungheim, Louis N.; Aube, Jeffrey; Scarry, Sarah M.; McDonald, Stacey L.; Li, Kelin; Perkowski, Andrew; Nguyen, Quyen; Dartois, Veronique; Zimmerman, Matthew; Olsen, David B.; Young, Katherine; Bonnett, Shilah; Joerss, Douglas; Parish, Tanya; Boshoff, Helena, I; Arora, Kriti; Barry, Clifton E., III; Guijarro, Laura; Anca, Sara; Rullas, Joaquin; Rodriguez-Salguero, Beatriz; Martinez-Martinez, Maria S.; Porras-De Francisco, Esther; Cacho, Monica; Barros-Aguirre, David; Smith, Paul; Berthel, Steven J.; Nathan, Carl; Bates, Robert H. 分享 收藏
6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis 6-氟苯基苯酰肼通过改变色氨酸的生物合成抑制结核分枝杆菌的生长 Consalvi, Sara; Venditti, Giulia; Zhu, Junhao; Boshoff, Helena, I; Arora, Kriti; De Logu, Alessandro; Ioerger, Thomas R.; Rubin, Eric J.; Biava, Mariangela; Poce, Giovanna 分享 收藏
Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis Xie, Yingda L.; de Jager, Veronique R.; Chen, Ray Y.; Dodd, Lori E.; Paripati, Praveen; Via, Laura E.; Follmann, Dean; Wang, Jing; Lumbard, Keith; Lahouar, Saher; Malherbe, Stephanus T.; Andrews, Jenna; Yu, Xiang; Goldfeder, Lisa C.; Cai, Ying; Arora, Kriti; Loxton, Andre G.; Vanker, Naadira; Duvenhage, Michael; Winter, Jill; Song, Taeksun; Walzl, Gerhard; Diacon, Andreas H.; Barry, Clifton E., III 分享 收藏
Tissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency Korol, Cecilia B.; Shallom, Shamira J.; Arora, Kriti; Boshoff, Helena I.; Freeman, Alexandra F.; King, Alejandra; Agrawal, Sonia; Daugherty, Sean C.; Jancel, Timothy; Kabat, Juraj; Ganesan, Sundar; Torrero, Marina N.; Sampaio, Elizabeth P.; Barry, Clifton, III; Holland, Steve M.; Tettelin, Herve; Rosenzweig, Sergio D.; Zelazny, Adrian M. 分享 收藏
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Synthesis, antitubercular evaluation, molecular docking and molecular dynamics studies of 4,6-disubstituted-2-oxo-dihydropyridine-3-carbonitriles Verma, Ruchi; Boshoff, Helena I. M.; Arora, Kriti; Bairy, Indira; Tiwari, Mradul; Bhat, Varadaraj G.; Shenoy, Gautham G. 分享 收藏
Synthesis, evaluation, molecular docking, and molecular dynamics studies of novel N-(4-[pyridin-2-yloxy]benzyl)arylamine derivatives as potential antitubercular agents Verma, Ruchi; Boshoff, Helena I. M.; Arora, Kriti; Bairy, Indira; Tiwari, Mradul; Bhat, Varadaraj G.; Shenoy, G. Gautham 分享 收藏
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C4-Phenylthio β-lactams: Effect of the chirality of the β-lactam ring on antimicrobial activity Kuskovsky, Rostislav; Lloyd, Dina; Arora, Kriti; Plotkin, Balbina J.; Green, Jacalyn M.; Boshoff, Helena I.; Barry, Clifton, III; Deschamps, Jeffrey; Konaklieva, Monika I. 分享 收藏
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Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-D-ribose 2′-Oxidase Oh, Sangmi; Park, Yumi; Engelhart, Curtis A.; Wallach, Joshua B.; Schnappinger, Dirk; Arora, Kriti; Manikkam, Michelle; Gac, Brian; Wang, Hongwu; Murgolo, Nicholas; Olsen, David B.; Goodwin, Michael; Sutphin, Michelle; Weiner, Danielle M.; Via, Laura E.; Boshoff, Helena I. M.; Barry, Clifton E., III 分享 收藏
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization Murugesan, Dinakaran; Ray, Peter C.; Bayliss, Tracy; Prosser, Gareth A.; Harrison, Justin R.; Green, Kirsteen; de Melo, Candice Soares; Feng, Tzu-Shean; Street, Leslie J.; Chibale, Kelly; Warner, Digby F.; Mizrahi, Valerie; Epemolu, Ola; Scullion, Paul; Ellis, Lucy; Riley, Jennifer; Shishikura, Yoko; Ferguson, Liam; Osuna-Cabello, Maria; Read, Kevin D.; Green, Simon R.; Lamprecht, Dirk A.; Finin, Peter M.; Steyn, Adrie J. C.; Ioerge, Thomas R.; Sacchettin, Jim; Rhee, Kyu Y.; Arora, Kriti; Barry, Clifton E., III; Wyatt, Paul G.; Boshoff, Helena I. M. 分享 收藏
Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c Moosa, Atica; Lamprecht, Dirk A.; Arora, Kriti; Barry, Clifton E., III; Boshoff, Helena L. M.; Ioerger, Thomas R.; Steyn, Adrie J. C.; Mizrahi, Valerie; Warner, Digby F. 分享 收藏
Respiratory Flexibility in Response to Inhibition of Cytochrome c Oxidase in Mycobacterium tuberculosis (vol 58, pg 6962, 2014) Arora, Kriti; Ochoa-Montano, Bernardo; Tsang, Patricia S.; Blundell, Tom L.; Dawes, Stephanie S.; Mizrahi, Valerie; Bayliss, Tracy; Mackenzie, Claire J.; Cleghorn, Laura A. T.; Ray, Peter C.; Wyatt, Paul G.; Uh, Eugene; Lee, Jinwoo; Barry, Clifton E., III; Boshoff, Helena I. 分享 收藏
Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes Costa, Diego L.; Namasivayam, Sivaranjani; Amaral, Eduardo P.; Arora, Kriti; Chao, Alex; Mittereder, Lara R.; Maiga, Mamoudou; Boshoff, Helena I.; Barry, Clifton E., III; Goulding, Celia W.; Andrade, Bruno B.; Sher, Alan 分享 收藏