logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
F

Fumiaki Yokokawa

Novartis
H指数:35
被引数:3,069

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-03-0116
OAAI
Taft, Benjamin R.; Yokokawa, Fumiaki; Kirrane, Tom; Mata, Anne-Catherine; Huang, Richard; Blaquiere, Nicole; Waldron, Grace; Zou, Bin; Simon, Oliver; Vankadara, Subramanyam; Chan, Wai Ling; Ding, Mei; Sim, Sandra; Straimer, Judith; Guiguemde, Armand; Lakshminarayana, Suresh B.; Jain, Jay Prakash; Bodenreider, Christophe; Thompson, Christopher; Lanshoeft, Christian; Shu, Wei; Fang, Eric; Qumber, Jafri; Chan, Katherine; Pei, Luying; Chen, Yen-Liang; Schulz, Hanna; Lim, Jessie; Abas, Siti Nurdiana; Ang, Xiaoman; Liu, Yugang; Angulo-Barturen, Inigo; Belen Jimenez-Diaz, Maria; Javier Gamo, Francisco; Crespo-Fernandez, Benigno; Rosenthal, Philip J.; Cooper, Roland A.; Tumwebaze, Patrick; Campos Aguiar, Anna Caroline; Campo, Brice; Campbell, Simon; Wagner, Jurgen; Diagana, Thierry T.; Sarko, Christopher
NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models

NITD-688是登革热病毒NS4B蛋白的泛血清型抑制剂，在临床前动物模型中显示出良好的药代动力学和疗效

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-02-0346
PREAI
Moquin, Stephanie A.; Simon, Oliver; Karuna, Ratna; Lakshminarayana, Suresh B.; Yokokawa, Fumiaki; Wang, Feng; Saravanan, Chandra; Zhang, Jin; Day, Craig W.; Chan, Katherine; Wang, Qing-Yin; Lu, Siyan; Dong, Hongping; Wan, Kah Fei; Lim, Siew Pheng; Liu, Wei; Seh, Cheah Chen; Chen, Yen-Liang; Xu, Haoying; Barkan, David T.; Kounde, Cyrille S.; Sim, Wei Lin Sandra; Wang, Gang; Yeo, Hui-Quan; Zou, Bin; Chan, Wai Ling; Ding, Mei; Song, Jae-Geun; Li, Min; Osborne, Colin; Blasco, Francesca; Sarko, Christopher; Beer, David; Bonamy, Ghislain M. C.; Sasseville, Vito G.; Shi, Pei-Yong; Diagana, Thierry T.; Yeung, Bryan K. S.; Gu, Feng
A Cyclic Phosphoramidate Prodrug of 2′-Deoxy-2′-Fluoro-2′-C- Methylguanosine for the Treatment of Dengue Virus Infection
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2020-11-178
OAAI
Karuna, Ratna; Yokokawa, Fumiaki; Wang, Keshi; Zhang, Jin; Xu, Haoying; Wang, Gang; Ding, Mei; Chan, Wai Ling; Ghafar, Nahdiyah Abdul; Leonardi, Andrea; Seh, Cheah Chen; Seah, Peck Gee; Liu, Wei; Srinivasa, Rao P. S.; Lim, Siew Pheng; Lakshminarayana, Suresh B.; Growcott, Ellie; Babu, Sreehari; Fenaux, Martijn; Zhong, Weidong; Gu, Feng; Shi, Pei-Yong; Blasco, Francesca; Chen, Yen-Liang
Antiviral Nucleotide Incorporation by Recombinant Human Mitochondrial RNA Polymerase Is Predictive of Increased In Vivo Mitochondrial Toxicity Risk
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2016-12-0115
OAAI
Fenaux, Martijn; Lin, Xiaodong; Yokokawa, Fumiaki; Sweeney, Zachary; Saunders, Oliver; Xie, Lili; Lim, Siew Pheng; Uteng, Marianne; Uehara, Kyoko; Warne, Robert; Gang, Wang; Jones, Christopher; Yendluri, Satya; Gu, Helen; Mansfield, Keith; Boisclair, Julie; Heimbach, Tycho; Catoire, Alexandre; Bracken, Kathryn; Weaver, Margaret; Moser, Heinz; Zhong, Weidong
Structure-Based Design of Substituted Piperidines as a New Class of Highly Efficacious Oral Direct Renin Inhibitors

基于结构设计的取代哌啶类高效口服直接肾素抑制剂

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2014-05-0828
OAAI
Ehara, Takeru; Irie, Osamu; Kosaka, Takatoshi; Kanazawa, Takanori; Breitenstein, Werner; Grosche, Philipp; Ostermann, Nils; Suzuki, Masaki; Kawakami, Shimpei; Konishi, Kazuhide; Hitomi, Yuko; Toyao, Atsushi; Gunji, Hirold; Cumin, Frederic; Schiering, Nikolaus; Wagner, Trixie; Rigel, Dean F.; Webb, Randy L.; Maibaum, Juergen; Yokokawa, Fumiaki
Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Novel Antitubercular Agents (vol 4, pg 451, 2013)
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2014-02-111
OAAI
Yokokawa, Fumiaki; Wang, Gang; Chan, Wai Ling; Ang, Shi Hua; Wong, Josephine; Ma, Ida; Rao, Srinivasa P. S.; Manjunatha, Ujjini; Lakshminarayana, Suresh B.; Herve, Maxime; Kounde, Cyrille; Tan, Bee Huat; Thayalan, Pamela; Dick, Thomas; Ng, Seow Hwee; Nanjundappa, Mahesh; Ravindran, Sindhu; Gee, Peck; Tan, Maria; Wei, Liu; Goh, Anne; Chen, Pei-Yu; Lee, Kok Sin; Zhang, Chen; Wagner, Trixie; Dix, Ina; Chatterjee, Arnab; Pethe, Kevin; Kuhen, Kelli; Glynne, Richard; Smith, Paul; Bifani, Pablo; Jiricek, Jan
Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2013-04-1145
OA
Yokokawa, Fumiaki; Wang, Gang; Chan, Wai Ling; Ang, Shi Hua; Wong, Josephine; Ma, Ida; Rao, Srinivasa P. S.; Manjunatha, Ujjini; Lakshminarayana, Suresh B.; Herve, Maxime; Kounde, Cyrille; Tan, Bee Huat; Thayalan, Pamela; Ng, Seow Hwee; Nanjundappa, Mahesh; Ravindran, Sindhu; Gee, Peck; Tan, Maria; Wei, Liu; Goh, Anne; Chen, Pei-Yu; Lee, Kok Sin; Zhong, Chen; Wagner, Trixie; Dix, Ina; Chatterjee, Arnab K.; Pethe, Kevin; Kuhen, Kelli; Glynne, Richard; Smith, Paul; Bifani, Pablo; Jiricek, Jan
Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2008-08-2936
PREAI
Irie, Osamu; Kosaka, Takatoshi; Ehara, Takeru; Yokokawa, Fumiaki; Kanazawa, Takanori; Hirao, Hajime; Iwasaki, Astuko; Sakaki, Junichi; Teno, Naoki; Hitomi, Yuko; Iwasaki, Genji; Fukaya, Hiroaki; Nonomura, Kazuhiko; Tanabe, Keiko; Koizumi, Shinichi; Uchiyama, Noriko; Bevan, Stuart J.; Malcangio, Marzia; Gentry, Clive; Fox, Alyson J.; Yaqoob, Mohammed; Culshaw, Andrew J.; Hallett, Allan

研究方向

暂未获取到该数据
P
Pei‐Yong Shi
H 指数:120论文数:635被引数:5.9万
S
Siew Pheng Lim
H 指数:49论文数:96被引数:6,807
T
Takayuki Shioiri
H 指数:54论文数:497被引数:1.1万
S
Suresh B. Lakshminarayana
H 指数:27论文数:53被引数:4,286
Y
Yen‐Liang Chen
H 指数:47论文数:239被引数:7,810
C
Cheah C. Seh
H 指数:12论文数:57被引数:923
W
Wai Ling Chan
H 指数:11论文数:18被引数:1,127
S
Shahul Nilar
H 指数:17论文数:57被引数:1,822
U
Ujjini H. Manjunatha
H 指数:32论文数:72被引数:4,752
H
Hongping Dong
H 指数:42论文数:71被引数:6,552