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D

Damian C. Crowther

astrazeneca
H指数:41
被引数:5,153

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A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response

抑制性eIF2B-eIF2(αP)复合物的分子稳定剂激活整合应激反应

Nature Communications
IF15.7
2026-05-060
OAAI
Fiona Shilliday; Miguel Gancedo-Rodrigo; Ginto George; Shintaro Aibara; Santosh Adhikari; Syedah Neha Ashraf; Evelyne J. Barrey; Paolo A. Centrella; Damian Crowther; Paige Dickson; Diana Gikunju; Marie-Aude Guié; John P. Guilinger; Anders Gunnarsson; Heather P. Harding; Christopher D. Hupp; Rachael Jetson; Anthony D. Keefe; JeeSoo Monica Kim; Richard J. Lewis; Taiana Maia de Oliveira; Jennifer Le-Marshall; Usha Narayanan; Katherine A. Nugai; Dušan Petrović; Emma Rivers; David Ron; Daisy Stringfellow; Karl Syson; Lewis Ward; John T. S. Yeoman; Yan Yu; Ying Zhang; Alisa Zyryanova; David J. Baker; Perla Breccia; John E. Linley
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease
NATURE COMMUNICATIONS
IF15.7
2024-06-014
OAAI
Xia, Zengjie; Prescott, Emily E.; Urbanek, Agnieszka; Wareing, Hollie E.; King, Marianne C.; Olerinyova, Anna; Dakin, Helen; Leah, Tom; Barnes, Katy A.; Matuszyk, Martyna M.; Dimou, Eleni; Hidari, Eric; Zhang, Yu P.; Lam, Jeff Y. L.; Danial, John S. H.; Strickland, Michael R.; Jiang, Hong; Thornton, Peter; Crowther, Damian C.; Ohtonen, Sohvi; Gomez-Budia, Mireia; Bell, Simon M.; Ferraiuolo, Laura; Mortiboys, Heather; Higginbottom, Adrian; Wharton, Stephen B.; Holtzman, David M.; Malm, Tarja; Ranasinghe, Rohan T.; Klenerman, David; De, Suman
Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer's disease

在阿尔茨海默氏病的早期阶段，整个大脑中都存在可溶性含淀粉样蛋白的聚集体

BRAIN COMMUNICATIONS
IF4.5
2021-07-0244
OAAI
Sideris, Dimitrios, I; Danial, John S. H.; Emin, Derya; Ruggeri, Francesco S.; Xia, Zengjie; Zhang, Yu P.; Lobanova, Evgeniia; Dakin, Helen; De, Suman; Miller, Alyssa; Sang, Jason C.; Knowles, Tuomas P. J.; Vendruscolo, Michele; Fraser, Graham; Crowther, Damian; Klenerman, David

研究方向

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