Jiangping Xu - Publications, H-index & Citations

Jiangping Xu

southern medical university - china

39H指数

168论文数

4.6K被引数

收录论文 64

发表时间

Aldose reductase inhibition suppresses microglial endoplasmic reticulum stress and ferritinophagy in ischemic stroke 醛糖还原酶抑制可抑制缺血性脑卒中中微胶质细胞的内质网应激和铁蛋白噬作用

Acta Pharmacologica Sinica

IF8.4

2026-04-01

PREAI

Tu, Xing-xing; Luo, Fu-lan; Deng, Ting-wei; Li, Jia-hui; Wang, Jia-kang; Xu, Jiang-ping; Wang, Hai-tao

Charting the spatial transcriptome of the human cerebral cortex at single-cell resolution 绘制人类大脑皮层单细胞分辨率的时空转录组图谱

Nature Communications

IF15.7

2025-08-19

OAAI

Songren Wei; Meng Luo; Pingping Wang; Rui Chen; Xiyun Jin; Chang Xu; Chenyang Li; Xiaoyu Lin; Zhaochun Xu; Hongxin Liu; Rui Cheng; Wenyi Yang; Yideng Cai; Guangfu Xue; Peng Huang; Zhigang Liu; Haoxiu Sun; Jiangping Xu; Qinghua Jiang

Discovery of Limonoids from Xylocarpus granatum as Potential Leads against Neuroinflammation

JOURNAL OF NATURAL PRODUCTS

IF3.6

2025-04-01

PREAI

Zhao, Wei; Luo, Fulan; Liu, Lifu; Zeng, Chunyuan; Wang, Haitao; Xu, Jiangping; Wu, Jun; Shen, Li

Glial changes and gene expression in Alzheimer's disease from snRNA-Seq and spatial transcriptomics 从snrna-seq和空间转录组学看阿尔茨海默病的神经胶质变化和基因表达

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2025-04-01

PREAI

Wei, Songren; Li, Chenyang; Li, Wenxuan; Yuan, Fumiao; Kong, Jingjing; Su, Xi; Huang, Peng; Guo, Hongbo; Xu, Jiangping; Sun, Haitao

Discovery of 7-alkoxybenzofurans as PDE4 inhibitors with hepatoprotective activity in D-GalN/LPS-induced hepatic sepsis

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-09-01

PREAI

Xia, Chuang; Wen, Huizhen; Zheng, Lei; Ni, Yujie; Bi, Huichang; Wang, Haitao; Xu, Jiangping; Zhou, Zhong-Zhen

Inhibition of phosphodiesterase 4 attenuates aquaporin 4 expression and astrocyte swelling following cerebral ischemia/reperfusion injury

GLIA

IF5.1

2024-05-24

PREAI

Chen, Kechun; Xu, Bingtian; Qiu, Shuqin; Long, Lu; Zhao, Qian; Xu, Jiangping; Wang, Haitao

Advances in the development of phosphodiesterase 7 inhibitors 磷酸二酯酶7抑制剂的研究进展

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-03-01

PREAI

Huang, Jia-Xi; Zhu, Bo -Lin; Xu, Jiang-Ping; Zhou, Zhong-Zhen

Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats

ACTA PHARMACOLOGICA SINICA

IF8.4

2022-10-13

OAAI

Xu, Bing-tian; Li, Meng-fan; Chen, Ke-chun; Li, Xing; Cai, Ning-bo; Xu, Jiang-ping; Wang, Hai-tao

Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-08-01

PREAI

Liu, Jie; Liu, Lu; Zheng, Lei; Feng, Kai-Wen; Wang, Hai-Tao; Xu, Jiang-Ping; Zhou, Zhong-Zhen

Lattice water provides hydrogen atom donor to form hydrate: A case study of chlorbipram: m-hydroxybenzoic acid (1:1) cocrystal

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2022-02-01

PREAI

Huang, Dandan; Yang, Dezhi; Lv, Yang; Zhou, Jianle; Li, Liang; Xu, Jiangping; Yang, Xuemei; Zhou, Zhengzheng

Roflupram attenuates α-synuclein-induced cytotoxicity and promotes the mitochondrial translocation of Parkin in SH-SY5Y cells overexpressing A53T mutant α-synuclein

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2022-02-01

PREAI

Zhong, Jiahong; Li, Mengfan; Xu, Jiangping; Dong, Wenli; Qin, Yunyun; Qiu, Shuqing; Li, Xing; Wang, Haitao

Discovery of Novel 3-Amino-4-alkoxyphenylketones as PDE4 Inhibitors with Improved Oral Bioavailability and Safety against Spatial Memory Impairments

ACS CHEMICAL NEUROSCIENCE

IF3.9

2022-01-20

PREAI

Xia, Chuang; He, Jia-Peng; Feng, Kai-Wen; Liu, Lu; Zheng, Lei; Wang, Hai-Tao; Xu, Jiang-Ping; Zhou, Zhong-Zhen

Discovery of novel trimethoxyphenylbenzo[d]oxazoles as dual tubulin/PDE4 inhibitors capable of inducing apoptosis at G2/M phase arrest in glioma and lung cancer cells

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-11-01

PREAI

Liu, Jie; Ye, Wan; Xu, Jiang-Ping; Wang, Hai-Tao; Li, Xiao-Fang; Wang, Wen-Ya; Zhou, Zhong-Zhen

Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models 在帕金森氏病模型中，Roflupram可防止鱼藤酮诱导的神经毒性并促进 α-突触核蛋白降解

ACTA PHARMACOLOGICA SINICA

IF8.4

2021-09-16

OAAI

Dong, Wen-li; Zhong, Jia-hong; Chen, Yun-qing; Xie, Jin-feng; Qin, Yun-yun; Xu, Jiang-ping; Cai, Ning-bo; Li, Meng-fan; Liu, Lu; Wang, Hai-tao

Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2021-02-01

PREAI

Xu, Bingtian; Xu, Jiangping; Cai, Ningbo; Li, Mengfan; Liu, Lu; Qin, Yunyun; Li, Xing; Wang, Haitao

Inhibition of phosphodiesterase-4 suppresses HMGB1/RAGE signaling pathway and NLRP3 inflammasome activation in mice exposed to chronic unpredictable mild stress

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2021-02-01

PREAI

Xie, Jinfeng; Bi, Bingtian; Qin, Yunyun; Dong, Wenli; Zhong, Jiahong; Li, Mengfan; Cheng, Yufang; Xu, Jiangping; Wang, Haitao

Fibrinogen is an Independent Risk Factor for White Matter Hyperintensities in CADASIL but not in Sporadic Cerebral Small Vessel Disease Patients 纤维蛋白原是CADASIL中白质高信号的独立危险因素，但在散发性脑小血管疾病患者中则不是。

AGING AND DISEASE

IF6.9

2021-01-01

OAAI

Guo, Xingfang; Deng, Bin; Zhong, Lizi; Xie, Fen; Qiu, Qing; Wei, Xiaobo; Wang, Wenya; Xu, Jiangping; Liu, Ganqiang; Hon, Wong Peter Tsun; Yenari, Midori A.; Zhu, Shuzhen; Wang, Qing

Roflupram, a novel phosphodiesterase 4 inhibitor, inhibits lipopolysaccharide-induced neuroinflammatory responses through activation of the AMPK/Sirt1 pathway

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2021-01-01

PREAI

Li, Dan; Xu, Jiangping; Qin, Yunyun; Cai, Ningbo; Cheng, Yufang; Wang, Haitao

AMI, an Indazole Derivative, Improves Parkinson's Disease by Inhibiting Tau Phosphorylation

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2020-11-19

OAAI

Zhang Mao; Zhu Wen-ting; Wang Hai-tao; Yu Hui; Lan Shi-yi; Xu Jiang-ping; Wang Wen-ya

Acute EPA-induced learning and memory impairment in mice is prevented by DHA

NATURE COMMUNICATIONS

IF15.7

2020-10-29

OAAI

Liu, Ji-Hong; Wang, Qian; You, Qiang-Long; Li, Ze-Lin; Hu, Neng-Yuan; Wang, Yan; Jin, Zeng-Lin; Li, Shu-Ji; Li, Xiao-Wen; Yang, Jian-Ming; Zhu, Xin-Hong; Dai, Yi-Fan; Xu, Jiang-Ping; Bai, Xiao-Chun; Gao, Tian-Ming

研究方向