Isabel Varela‐Nieto - Publications, H-index & Citations

Isabel Varela‐Nieto

Instituto de Investigaciones Biomédicas Sols-Morreale

46H指数

286论文数

1.5W被引数

收录论文 75

发表时间

Neuroprotective potential of a TrkB-FL-derived cell-penetrating peptide in cochlear synaptopathy and noise-induced hearing loss TrkB-FL衍生的穿膜肽在耳蜗突触病和噪声性听力损失中的神经保护潜力

Molecular Medicine

IF6.4

2026-06-29

OAAI

Elena Torres-Campos; Isabel Varela-Nieto; Margarita Díaz-Guerra

NLRP3 inflammasome and hearing loss: from mechanisms to therapies NLRP3炎性小体与听力损失：从机制到疗法

Journal of Neuroinflammation

IF10.1

2025-10-06

OAAI

Silvia Murillo-Cuesta; Elena Seoane; Blanca Cervantes; Jose Manuel Zubeldia; Isabel Varela-Nieto

A murine model for the del(GJB6-D13S1830) deletion recapitulating the phenotype of human DFNB1 hearing impairment: generation and functional and histopathological study 人类DFNB1听力损伤表型的del(GJB6-D13S1830) 缺失鼠模型: 产生和功能及组织病理学研究

BMC GENOMICS

IF3.7

2024-04-11

OAAI

Dominguez-Ruiz, Maria; Murillo-Cuesta, Silvia; Contreras, Julio; Cantero, Marta; Garrido, Gema; Martin-Bernardo, Belen; Gomez-Rosas, Elena; Fernandez, Almudena; del Castillo, Francisco J.; Montoliu, Lluis; Varela-Nieto, Isabel; del Castillo, Ignacio

Dysfunction of programmed embryo senescence is linked to genetic developmental defects

DEVELOPMENT

IF3.6

2023-05-03

OAAI

de Lope, Cristina; Garcia-Lucena, Rebeca; Magarinos, Marta; Leon, Yolanda; Casa-Rodriguez, Nuria; Contreras, Nuria; Escudero-Iriarte, Carmen; Varela-Nieto, Isabel; Maire, Pascal; Palmero, Ignacio

Editorial: Otologic Trauma, Pathology, and Therapy

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2022-04-13

OAAI

Landegger, Lukas D.; Fujita, Takeshi; Jan, Taha A.; Varela-Nieto, Isabel

Editorial: The Role of Cellular Senescence in Health and Disease

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2022-03-30

OAAI

Palmero, Ignacio; Gorgoulis, Vassilis; Varela-Nieto, Isabel

Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2021-09-01

OAAI

Varela-Nieto, Isabel; Murillo-Cuesta, Silvia; Lourdes Rodriguez-de la Rosa; Jesus Oset-Gasque, Maria; Marco-Contelles, Jose

Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea

ANTIOXIDANTS

IF6.6

2021-08-25

OAAI

Bermudez-Munoz, Jose M.; Celaya, Adelaida M.; Garcia-Mato, Angela; Munoz-Espin, Daniel; Rodriguez-de la Rosa, Lourdes; Serrano, Manuel; Varela-Nieto, Isabel

IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss IGF-1单倍功能不全导致与年龄相关的慢性耳蜗炎症并增加噪声性听力损失

CELLS

IF5.2

2021-07-03

OAAI

Celaya, Adelaida M.; Rodriguez-de La Rosa, Lourdes; Bermudez-Munoz, Jose M.; Zubeldia, Jose M.; Roma-Mateo, Carlos; Avendano, Carlos; Pallardo, Federico, V; Varela-Nieto, Isabel

Therapeutic efficiency of the APAF-1 antagonist LPT99 in a rat model of cisplatin-induced hearing loss

CLINICAL AND TRANSLATIONAL MEDICINE

IF6.8

2021-04-05

OAAI

Murillo-Cuesta, Silvia; Celaya, Adelaida M.; Cervantes, Blanca; Bermudez-Munoz, Jose M.; Rodriguez-de la Rosa, Lourdes; Contreras, Julio; Sanchez-Perez, Isabel; Varela-Nieto, Isabel

G6PD overexpression protects from oxidative stress and age-related hearing loss

AGING CELL

IF7.1

2020-11-22

OAAI

Bermudez-Munoz, Jose M.; Celaya, Adelaida M.; Hijazo-Pechero, Sara; Wang, Jing; Serrano, Manuel; Varela-Nieto, Isabel

Drug development for noise-induced hearing loss

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2020-08-25

PREAI

Varela-Nieto, Isabel; Murillo-Cuesta, Silvia; Calvino, Miryam; Cediel, Rafael; Lassaletta, Luis

Otic Neurogenesis Is Regulated by TGFβ in a Senescence-Independent Manner

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2020-08-17

OAAI

Magarinos, Marta; Barajas-Azpeleta, Raquel; Varela-Nieto, Isabel; R. Aburto, Maria

Folic acid as preventive therapy for hearing loss: effect of ototoxic drug consumption

PROCEEDINGS OF THE NUTRITION SOCIETY

IF4.5

2020-06-10

OAAI

Morais-Moreno, Carmen; del Pilar Garzon-Riveros, Maria; Murillo-Cuesta, Silvia; Rodriguez-de la Rosa, Lourdes; Montero, Ana; Angeles Pajares, Maria; Perez-Miguelsanz, Julia; Varela-Nieto, Isabel; Varela-Moreiras, Gregorio; Partearroyo, Teresa

Solid Lipid Nanoparticles Loaded with Glucocorticoids Protect Auditory Cells from Cisplatin-Induced Ototoxicity

JOURNAL OF CLINICAL MEDICINE

IF2.9

2019-09-14

OAAI

Cervantes, Blanca; Arana, Lide; Murillo-Cuesta, Silvia; Bruno, Marina; Alkorta, Itziar; Varela-Nieto, Isabel

TGFβ2-induced senescence during early inner ear development

SCIENTIFIC REPORTS

IF3.9

2019-04-11

OAAI

Gibaja, Alejandro; Aburto, Maria R.; Pulido, Sara; Collado, Manuel; Hurle, Juan M.; Varela-Nieto, Isabel; Magarinos, Marta

Deficit of mitogen-activated protein phosphatase 1 (DUSP1) accelerates progressive hearing loss

ELIFE

IF0

2019-04-02

OAAI

Celaya, Adelaide M.; Sanchez-Perez, Isabel; Bermudez-Munoz, Jose M.; Rodriguez-de la Rosa, Lourdes; Pintado-Berninches, Laura; Perona, Rosario; Murillo-Cuesta, Silvia; Varela-Nieto, Isabel

Neuroglial Involvement in Abnormal Glutamate Transport in the Cochlear Nuclei of the Igf1-/- Mouse

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2019-03-01

OAAI

Fuentes-Santamaria, Veronica; Alvarado, Juan C.; Rodriguez-de la Rosa, Lourdes; Juiz, Jose M.; Varela-Nieto, Isabel

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia

FASEB JOURNAL

IF4.2

2019-02-12

OAAI

Partearroyo, Teresa; Murillo-Cuesta, Silvia; Vallecillo, Nestor; Bermudez-Munoz, Jose M.; Rodriguez-de la Rosa, Lourdes; Mandruzzato, Giacomo; Celaya, Adelaida M.; Zeisel, Steven H.; Pajares, Maria A.; Varela-Moreiras, Gregorio; Varela-Nieto, Isabel

Modelling physical resilience in ageing mice

MECHANISMS OF AGEING AND DEVELOPMENT

IF5.1

2019-01-01

OAAI

Schosserer, Markus; Banks, Gareth; Dogan, Soner; Dungel, Peter; Fernandes, Adelaide; Presen, Darja Marolt; Matheu, Ander; Osuchowski, Marcin; Potter, Paul; Sanfeliu, Coral; Tuna, Bilge Guvenc; Varela-Nieto, Isabel; Bellantuono, Ilaria

研究方向