未登录 Phase-1 study of vamotinib (PF-114), a 3rd generation BCR::ABL1 tyrosine kinase-inhibitor, in chronic myeloid leukaemia vamotinib（PF-114）的I期研究，该药是一种第三代BCR::ABL1酪氨酸激酶抑制剂，用于慢性粒细胞白血病。 Turkina, Anna; Vinogradova, Olga; Lomaia, Elza; Shatokhina, Evgeniya; Shukhov, Oleg; Chelysheva, Ekaterina; Shikhbabaeva, Dzhariyat; Nemchenko, Irina; Petrova, Anna; Bykova, Anastasiya; Siordiya, Nadiya; Shuvaev, Vasily; Mikhailov, Ilya; Novikov, Fedor; Shulgina, Veronika; Hochhaus, Andreas; Ottmann, Oliver; Cortes, Jorge; Gale, Robert Peter; Chilov, Ghermes 分享 收藏
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Phase Ib study of sabatolimab (MBG453), a novel immunotherapy targeting TIM-3 antibody, in combination with decitabine or azacitidine in high- or very high-risk myelodysplastic syndromes 针对TIM-3抗体的新型免疫疗法sabatolimab (MBG453) 与地西他滨或阿扎胞苷联合治疗高危或极高危骨髓增生异常综合征的Ib期研究 Brunner, Andrew M.; Esteve, Jordi; Porkka, Kimmo; Knapper, Steve; Traer, Elie; Scholl, Sebastian; Garcia-Manero, Guillermo; Vey, Norbert; Wermke, Martin; Janssen, Jeroen J. W. M.; Narayan, Rupa; Fleming, Shaun; Loo, Sun; Tovar, Natalia; Kontro, Mika; Ottmann, Oliver G.; Naidu, Purushotham; Sun, Haiying; Han, May; White, Roisin; Zhang, Na; Mohammed, Anisa; Sabatos-Peyton, Catherine A.; Steensma, David P.; Rinne, Mikael L.; Borate, Uma M.; Wei, Andrew H. 分享 收藏
Asciminib monotherapy in patients with CML-CP without BCR::ABL1 T315I mutations treated with at least two prior TKIs: 4-year phase 1 safety and efficacy results Asciminib单药治疗无BCR的cml-cp患者::ABL1 T315I突变与至少两个先前的TKIs治疗: 4年1期安全性和有效性结果 Mauro, Michael J.; Hughes, Timothy P.; Kim, Dong-Wook; Rea, Delphine; Cortes, Jorge E.; Hochhaus, Andreas; Sasaki, Koji; Breccia, Massimo; Talpaz, Moshe; Ottmann, Oliver; Minami, Hironobu; Goh, Yeow Tee; DeAngelo, Daniel J.; Heinrich, Michael C.; Gomez-Garcia de Soria, Valle; le Coutre, Philipp; Mahon, Francois-Xavier; Janssen, Jeroen J. W. M.; Deininger, Michael; Shanmuganathan, Naranie; Geyer, Mark B.; Cacciatore, Silvia; Polydoros, Fotis; Agrawal, Nithya; Hoch, Matthias; Lang, Fabian 分享 收藏
Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation Chiriches, Claudia; Nicolaisen, Nathalie; Wieske, Maria; Elhaddad, Heba; Mehmetbeyoglu, Ecmel; Alvares, Caroline; Becher, Doerte; Hole, Paul; Ottmann, Oliver Gerhard; Ruthardt, Martin 分享 收藏
Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia Chiriches, Claudia; Khan, Dilawar; Wieske, Maria; Guillen, Nathalie; Rokicki, Michal; Guy, Carol; Wilson, Marieangela; Heesom, Kate J.; Ottmann, Oliver Gerhard; Ruthardt, Martin 分享 收藏
Unified classification and risk-stratification in Acute Myeloid Leukemia 急性髓系白血病的统一分类与风险分层 Tazi, Yanis; Ossa, Juan Arango; Zhou, Yangyu; Bernard, Elsa; Thomas, Ian; Gilkes, Amanda; Freeman, Sylvie; Pradat, Yoann; Johnson, Sean; Hills, Robert; Dillon, Richard; Levine, Max; Leongamornlert, Dan; Butler, Adam; Ganser, Arnold; Bullinger, Lars; Doehner, Konstanze; Ottmann, Oliver; Adams, Richard; Doehner, Hartmut; Campbell, Peter; Burnett, Alan; Dennis, Michael; Russell, Nigel; Devlin, Sean; Huntly, Brian; Papaemmanuil, Elli 分享 收藏
Idasanutlin plus cytarabine in relapsed or refractory acute myeloid leukemia: results of the MIRROS trial Konopleva, Marina Y.; Roellig, Christoph; Cavenagh, Jamie; Deeren, Dries; Girshova, Larisa; Krauter, Juergen; Martinelli, Giovanni; Montesinos, Pau; Schaefer, Jonas A.; Ottmann, Oliver; Petrini, Mario; Pigneux, Arnaud; Rambaldi, Alessandro; Recher, Christian; Rodriguez-Veiga, Rebeca; Taussig, David; Vey, Norbert; Yoon, Sung-Soo; Ott, Marion; Muehlbauer, Susanne; Beckermann, Benjamin M.; Catalani, Olivier; Genevray, Magali; Mundt, Kirsten; Jamois, Candice; Fenaux, Pierre; Wei, Andrew H. 分享 收藏
The impact of COVID-19 on cancer care and oncology clinical research: an experts' perspective Sessa, C.; Cortes, J.; Conte, P.; Cardoso, F.; Choueiri, T.; Dummer, R.; Lorusso, P.; Ottmann, O.; Ryll, B.; Mok, T.; Tempero, M.; Comis, S.; Oliva, C.; Peters, S.; Tabernero, J. 分享 收藏
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Adjunctive Volasertib in Patients With Acute Myeloid Leukemia not Eligible for Standard Induction Therapy: A Randomized, Phase 3 Trial Dohner, Hartmut; Symeonidis, Argiris; Deeren, Dries; Demeter, Judit; Sanz, Miguel A.; Anagnostopoulos, Achilles; Esteve, Jordi; Fiedler, Walter; Porkka, Kimmo; Kim, Hee-Je; Lee, Je-Hwan; Usuki, Kensuke; D'Ardia, Stefano; Won Jung, Chul; Salamero, Olga; Horst, Heinz-August; Recher, Christian; Rousselot, Philippe; Sandhu, Irwindeep; Theunissen, Koen; Thol, Felicitas; Dohner, Konstanze; Teleanu, Veronica; DeAngelo, Daniel J.; Naoe, Tomoki; Sekeres, Mikkael A.; Belsack, Valerie; Ge, Miaomiao; Taube, Tillmann; Ottmann, Oliver G. 分享 收藏
Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K Mian, Afsar Ali; Haberbosch, Isabella; Khamaisie, Hazem; Agbarya, Abed; Pietsch, Larissa; Eshel, Elizabeh; Najib, Dally; Chiriches, Claudia; Ottmann, Oliver Gerhard; Hantschel, Oliver; Biondi, Ricardo M.; Ruthardt, Martin; Mahajna, Jamal 分享 收藏
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Long-term follow-up of blinatumomab in patients with relapsed/refractory Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukaemia: Final analysis of ALCANTARA study Martinelli, Giovanni; Boissel, Nicolas; Chevallier, Patrice; Ottmann, Oliver; Goekbuget, Nicola; Rambaldi, Alessandro; Ritchie, Ellen K.; Papayannidis, Cristina; Tuglus, Catherine A.; Morris, Joan D.; Stein, Anthony 分享 收藏
Dynamics of mutations in patients with essential thrombocythemia treated with imetelstat Leibundgut, Elisabeth Oppliger; Haubitz, Monika; Burington, Bart; Ottmann, Oliver G.; Spitzer, Gary; Odenike, Olatoyosi; McDevitt, Michael A.; Roeth, Alexander; Snyder, David S.; Baerlocher, Gabriela M. 分享 收藏
Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B cell non-Hodgkin lymphoma (vol 32, pg 861, 2020) Kroschinsky, Frank; Middeke, Jan Moritz; Janz, Martin; Lenz, Georg; Witzens-Harig, Mathias; Bouabdallah, Reda; La Rosee, Paul; Viardot, Andreas; Salles, Gilles; Kim, Seok Jin; Kim, Tae Min; Ottmann, Oliver; Chromik, Joerg; Quinson, Anne-Marie; von Wangenheim, Ute; Burkard, Ute; Berk, Andreas; Schmitz, Norbert 分享 收藏
Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma (vol 45, pg 810, 2020) Kroschinsky, Frank; Middeke, Jan Moritz; Janz, Martin; Lenz, Georg; Witzens-Harig, Mathias; Bouabdallah, Reda; La Rosee, Paul; Viardot, Andreas; Salles, Gilles; Kim, Seok Jin; Kim, Tae Min; Ottmann, Oliver; Chromik, Joerg; Quinson, Anne-Marie; von Wangenheim, Ute; Burkard, Ute; Berk, Andreas; Schmitz, Norbert 分享 收藏
Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma Kroschinsky, Frank; Middeke, Jan Moritz; Janz, Martin; Lenz, Georg; Witzens-Harig, Mathias; Bouabdallah, Reda; La Rosee, Paul; Viardot, Andreas; Salles, Gilles; Kim, Seok Jin; Kim, Tae Min; Ottmann, Oliver; Chromik, Joerg; Quinson, Anne-Marie; von Wangenheim, Ute; Burkard, Ute; Berk, Andreas; Schmitz, Norbert 分享 收藏
Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1 (vol 32, pg 345, 2019) Pfeifer, H.; Cazzaniga, G.; van der Velden, V. H. J.; Cayuela, J. M.; Schafer, B.; Spinelli, O.; Akiki, S.; Avigad, S.; Bendit, I.; Borg, K.; Cave, H.; Elia, L.; Reshmi, S. C.; Gerrard, G.; Hayette, S.; Hermanson, M.; Juh, A.; Jurcek, T.; Chillon, M. C.; Homburg, C.; Martinelli, G.; Kairisto, V.; Lange, T.; Lion, T.; Mueller, M. C.; Pane, F.; Rai, L.; Damm-Welk, C.; Sacha, T.; Schnittger, S.; Touloumenidou, T.; Valerhaugen, H.; Vandenberghe, P.; Zuna, J.; Serve, H.; Herrmann, E.; Markovic, S.; van Dongen, J. J. M.; Ottmann, O. G. 分享 收藏
Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure Asciminib治疗ABL激酶抑制剂失败后的慢性粒细胞白血病 Hughes, T. P.; Mauro, M. J.; Cortes, J. E.; Minami, H.; Rea, D.; DeAngelo, D. J.; Breccia, M.; Goh, Y. -T.; Talpaz, M.; Hochhaus, A.; le Coutre, P.; Ottmann, O.; Heinrich, M. C.; Steegmann, J. L.; Deininger, M. W. N.; Janssen, J. J. W. M.; Mahon, F. -X.; Minami, Y.; Yeung, D.; Ross, D. M.; Tallman, M. S.; Park, J. H.; Druker, B. J.; Hynds, D.; Duan, Y.; Meille, C.; Hourcade-Potelleret, F.; Vanasse, K. G.; Lang, F.; Kim, D. -W. 分享 收藏
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