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H

Hendrik J. Kuiken

Netherlands Cancer Institute
H指数:12
被引数:963

个人简介

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工作经历

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荣誉奖项

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DOT1L Shapes ncPRC1-Target Gene Repression to Maintain Germinal Center B-Cell Identity of Diffuse Large B-cell Lymphoma

DOT1L调控ncPRC1靶基因抑制以维持弥漫性大B细胞淋巴瘤的生发中心B细胞特性

Blood
IF23.1
2026-06-020
PRE
Camiel Göbel; Rachele Niccolai; Sebastian Gregoricchio; Marnix H. P. de Groot; Stijn Kneefel; Maaike Kreft; Hendrik J. Kuiken; Cor Lieftink; Nils Eickhoff; Liesbeth Hoekman; Onno Bleijerveld; Wilbert Zwart; Roderick L. Beijersbergen; Fred van Leeuwen; Heinz Jacobs
Cholesterol biosynthesis as a drug-induced vulnerability in diffuse large B cell lymphoma insensitive to EZH2 inhibition

胆固醇生物合成作为对EZH2抑制不敏感的弥漫性大B细胞淋巴瘤的药物诱导易感靶点

Neoplasia
IF7.7
2025-10-270
OAAI
Rachele Niccolai; Camiel Göbel; Klevis Ndoj; Maaike Kreft; Hendrik J. Kuiken; Cor Lieftink; Ben Morris; Sietse D. Yska; Sebastian Hendrix; Bram van den Broek; Vincent Pappalardo; Marie José Kersten; Roderick L. Beijersbergen; Noam Zelcer; Fred van Leeuwen; Heinz Jacobs
Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy
CANCER DISCOVERY
IF33.3
2024-03-266
OAAI
Dias, Matheus Henrique; Friskes, Anoek; Wang, Siying; Neto, Joao M. Fernandes; van Gemert, Frank; Mourragui, Soufiane; Papagianni, Chrysa; Kuiken, Hendrik J.; Mainardi, Sara; Alvarez-Villanueva, Daniel; Lieftink, Cor; Morris, Ben; Dekker, Anna; van Dijk, Emma; Wilms, Lieke H. S.; da Silva, Marcelo S.; Jansen, Robin A.; Mulero-Sanchez, Antonio; Malzer, Elke; Vidal, August; Santos, Cristina; Salazar, Ramon; Wailemann, Rosangela A. M.; Torres, Thompson E. P.; De Conti, Giulia; Raaijmakers, Jonne A.; Snaebjornsson, Petur; Yuan, Shengxian; Qin, Wenxin; Kovach, John S.; Armelin, Hugo A.; te Riele, Hein; van Oudenaarden, Alexander; Jin, Haojie; Beijersbergen, Roderick L.; Villanueva, Alberto; Medema, Rene H.; Bernards, Rene
Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
CELL REPORTS MEDICINE
IF10.6
2024-03-018
OAAI
Chen, Mengnuo; Mainardi, Sara; Lieftink, Cor; Velds, Arno; de Rink, Iris; Yang, Chen; Kuiken, Hendrik J.; Morris, Ben; Edwards, Finn; Jochems, Fleur; van Tellingen, Olaf; Boeije, Manon; Proost, Natalie; Jansen, Robin A.; Qin, Shifan; Jin, Haojie; van der Mijn, J. C. Koen; Schepers, Arnout; Venkatesan, Subramanian; Qin, Wenxin; Beijersbergen, Roderick L.; Wang, Liqin; Bernards, Rene
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts

人类TNBC模型的克隆种群在不同的环境中显示出显着的功能异质性和不同的生长动力学

ONCOGENE
IF7.3
2021-10-266
OA
Kuiken, Hendrik J.; Dhakal, Sabin; Selfors, Laura M.; Friend, Chandler M.; Zhang, Tian; Callari, Maurizio; Schackmann, Ron C. J.; Gray, G. Kenneth; Crowdis, Jett; Bhang, Hyo-Eun C.; Baslan, Timour; Stegmeier, Frank; Gygi, Steven P.; Caldas, Carlos; Brugge, Joan S.
Transient commensal clonal interactions can drive tumor metastasis
NATURE COMMUNICATIONS
IF15.7
2020-11-1633
OAAI
Naffar-Abu Amara, Suha; Kuiken, Hendrik J.; Selfors, Laura M.; Butler, Timothy; Leung, Marco L.; Leung, Cheuk T.; Kuhn, Elaine P.; Kolarova, Teodora; Hage, Carina; Ganesh, Kripa; Panayiotou, Richard; Foster, Rosemary; Rueda, Bo R.; Aktipis, Athena; Spellman, Paul; Ince, Tan A.; Xiu, Joanne; Oberley, Matthew; Gatalica, Zoran; Navin, Nicholas; Mills, Gordon B.; Bronson, Rodrick T.; Brugge, Joan S.

研究方向

暂未获取到该数据
R
Roderick L. Beijersbergen
H 指数:59论文数:361被引数:2.3万
J
Joan S. Brugge
H 指数:126论文数:598被引数:5.5万
C
Cor Lieftink
H 指数:33论文数:250被引数:6,057
L
Laura M. Selfors
H 指数:32论文数:152被引数:5,021
R
René Bernards
H 指数:111论文数:884被引数:7.8万
G
G. Kenneth Gray
H 指数:13论文数:49被引数:1,482
B
Ben Morris
H 指数:22论文数:142被引数:2,108
C
Chandler M. Friend
H 指数:1论文数:7被引数:9
L
Liqin Wang
H 指数:33论文数:176被引数:6,425
金
金浩杰
H 指数:37论文数:150被引数:6,811