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N

Natalie Brajanovski

Peter MacCallum Cancer Centre
H指数:10
被引数:1,173

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The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

RNA聚合酶I转录抑制剂CX-5461通过增强同源重组熟练的高级浆液性卵巢癌中的DNA损伤反应来与拓扑异构酶1抑制协同作用

BRITISH JOURNAL OF CANCER
IF6.8
2020-11-1130
OAAI
Yan, Shunfei; Xuan, Jiachen; Brajanovski, Natalie; Tancock, Madeleine R. C.; Madhamshettiwar, Piyush B.; Simpson, Kaylene J.; Ellis, Sarah; Kang, Jian; Cullinane, Carleen; Sheppard, Karen E.; Hannan, Katherine M.; Hannan, Ross D.; Sanij, Elaine; Pearson, Richard B.; Chan, Keefe T.
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

CX-5461激活DNA损伤反应并证明在高级别浆液性卵巢癌中的治疗效果

NATURE COMMUNICATIONS
IF15.7
2020-05-2697
OAAI
Sanij, Elaine; Hannan, Katherine M.; Xuan, Jiachen; Yan, Shunfei; Ahern, Jessica E.; Trigos, Anna S.; Brajanovski, Natalie; Son, Jinbae; Chan, Keefe T.; Kondrashova, Olga; Lieschke, Elizabeth; Wakefield, Matthew J.; Frank, Daniel; Ellis, Sarah; Cullinane, Carleen; Kang, Jian; Poortinga, Gretchen; Nag, Purba; Deans, Andrew J.; Khanna, Kum Kum; Mileshkin, Linda; McArthur, Grant A.; Soong, John; Berns, Els M. J. J.; Hannan, Ross D.; Scott, Clare L.; Sheppard, Karen E.; Pearson, Richard B.
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-08-2291
OAAI
AbuHammad, Shatha; Cullinane, Carleen; Martin, Claire; Bacolas, Zoe; Ward, Teresa; Chen, Huiqin; Slater, Alison; Ardley, Kerry; Kirby, Laura; Chan, Keefe T.; Brajanovski, Natalie; Smith, Lorey K.; Rao, Aparna D.; Lelliott, Emily J.; Kleinschmidt, Margarete; Vergara, Ismael A.; Papenfuss, Anthony T.; Lau, Peter; Ghosh, Prerana; Haupt, Sue; Haupt, Ygal; Sanij, Elaine; Poortinga, Gretchen; Pearson, Richard B.; Falk, Hendrik; Curtis, David J.; Stupple, Paul; Devlin, Mark; Street, Ian; Davies, Michael A.; McArthur, Grant A.; Sheppard, Karen E.
First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study
CANCER DISCOVERY
IF33.3
2019-08-01129
OAAI
Khot, Amit; Brajanovski, Natalie; Cameron, Donald P.; Hein, Nadine; Maclachlan, Kylee H.; Sanij, Elaine; Lim, John; Soong, John; Link, Emma; Blombery, Piers; Thompson, Ella R.; Fellowes, Andrew; Sheppard, Karen E.; McArthur, Grant A.; Pearson, Richard B.; Hannan, Ross D.; Poortinga, Gretchen; Harrison, Simon J.
Palbociclib synergizes with BRAF and MEK inhibitors in treatment naive melanoma but not after the development of BRAF inhibitor resistance

Palbociclib与BRAF和MEK抑制剂协同治疗幼稚黑色素瘤，但在BRAF抑制剂耐药性发展后没有

INTERNATIONAL JOURNAL OF CANCER
IF4.7
2018-01-0359
OAAI
Martin, Claire A.; Cullinane, Carleen; Kirby, Laura; Abuhammad, Shatha; Lelliott, Emily J.; Waldeck, Kelly; Young, Richard J.; Brajanovski, Natalie; Cameron, Donald P.; Walker, Rachael; Sanij, Elaine; Poortinga, Gretchen; Hannan, Ross D.; Pearson, Richard B.; Hicks, Rodney J.; McArthur, Grant A.; Sheppard, Karen E.

研究方向

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R
Richard B. Pearson
H 指数:74论文数:325被引数:1.7万
E
Elaine Sanij
H 指数:31论文数:111被引数:4,886
G
Grant A. McArthur
H 指数:102论文数:899被引数:8.0万
R
Ross D. Hannan
H 指数:62论文数:336被引数:1.2万
K
Karen E. Sheppard
H 指数:35论文数:192被引数:5,020
G
Gretchen Poortinga
H 指数:24论文数:90被引数:3,672
C
Carleen Cullinane
H 指数:53论文数:369被引数:9,288
K
Keefe T. Chan
H 指数:22论文数:92被引数:2,692
J
Jian Kang
H 指数:55论文数:286被引数:1.4万
D
Donald P. Cameron
H 指数:40论文数:159被引数:6,103