Sanij, Elaine; Hannan, Katherine M.; Xuan, Jiachen; Yan, Shunfei; Ahern, Jessica E.; Trigos, Anna S.; Brajanovski, Natalie; Son, Jinbae; Chan, Keefe T.; Kondrashova, Olga; Lieschke, Elizabeth; Wakefield, Matthew J.; Frank, Daniel; Ellis, Sarah; Cullinane, Carleen; Kang, Jian; Poortinga, Gretchen; Nag, Purba; Deans, Andrew J.; Khanna, Kum Kum; Mileshkin, Linda; McArthur, Grant A.; Soong, John; Berns, Els M. J. J.; Hannan, Ross D.; Scott, Clare L.; Sheppard, Karen E.; Pearson, Richard B.

Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-08-2291

OAAI

AbuHammad, Shatha; Cullinane, Carleen; Martin, Claire; Bacolas, Zoe; Ward, Teresa; Chen, Huiqin; Slater, Alison; Ardley, Kerry; Kirby, Laura; Chan, Keefe T.; Brajanovski, Natalie; Smith, Lorey K.; Rao, Aparna D.; Lelliott, Emily J.; Kleinschmidt, Margarete; Vergara, Ismael A.; Papenfuss, Anthony T.; Lau, Peter; Ghosh, Prerana; Haupt, Sue; Haupt, Ygal; Sanij, Elaine; Poortinga, Gretchen; Pearson, Richard B.; Falk, Hendrik; Curtis, David J.; Stupple, Paul; Devlin, Mark; Street, Ian; Davies, Michael A.; McArthur, Grant A.; Sheppard, Karen E.

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

CANCER DISCOVERY

IF33.3

2019-08-01129

OAAI

A functional genetic screen defines the AKT-induced senescence signaling network

CELL DEATH AND DIFFERENTIATION

IF15.4

2019-07-0840

OAAI

Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation

COMMUNICATIONS BIOLOGY

IF5.1

2019-01-2836

OAAI

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

NATURE COMMUNICATIONS

IF15.7

2018-09-28210

OAAI

Kondrashova, Olga; Topp, Monique; Nesic, Ksenija; Lieschke, Elizabeth; Ho, Gwo-Yaw; Harrell, Maria, I; Zapparoli, Giada, V; Hadley, Alison; Holian, Robert; Boehm, Emma; Heong, Valerie; Sanij, Elaine; Pearson, Richard B.; Krais, John J.; Johnson, Neil; McNally, Orla; Ananda, Sumitra; Alsop, Kathryn; Hutt, Karla J.; Kaufmann, Scott H.; Lin, Kevin K.; Harding, Thomas C.; Traficante, Nadia; deFazio, Anna; McNeish, Lain A.; Bowtell, David D.; Swisher, Elizabeth M.; Dobrovic, Alexander; Wakefield, Matthew J.; Scott, Clare L.; Chenevix-Trench, G.; Green, A.; Webb, P.; Gertig, D.; Fereday, S.; Moore, S.; Hung, J.; Harrap, K.; Sadkowsky, T.; Pandeya, N.; Malt, M.; Mellon, A.; Robertson, R.; Vanden Bergh, T.; Jones, M.; Mackenzie, P.; Maidens, J.; Nattress, K.; Chiew, Y. E.; Stenlake, A.; Sullivan, H.; Alexander, B.; Ashover, P.; Brown, S.; Corrish, T.; Green, L.; Jackman, L.; Ferguson, K.; Martin, K.; Martyn, A.; Ranieri, B.; White, J.; Jayde, V; Mamers, P.; Bowes, L.; Galletta, L.; Giles, D.; Hendley, J.; Schmidt, T.; Shirley, H.; Ball, C.; Young, C.; Viduka, S.; Tran, H.; Bilic, S.; Glavinas, L.; Brooks, J.; Stuart-Harris, R.; Kirsten, F.; Rutovitz, J.; Clingan, P.; Glasgow, A.; Proietto, A.; Braye, S.; Otton, G.; Shannon, J.; Bonaventura, T.; Stewart, J.; Begbie, S.; Friedlander, M.; Bell, D.; Baron-Hay, S.; Ferrier, A.; Gard, G.; Nevell, D.; Pavlakis, N.; Valmadre, S.; Young, B.; Camaris, C.; Crouch, R.; Edwards, L.; Hacker, N.; Marsden, D.; Robertson, G.; Beale, P.; Beith, J.; Carter, J.; Dalrymple, C.; Houghton, R.; Russell, P.; Links, M.; Grygiel, J.; Hill, J.; Brand, A.; Byth, K.; Jaworski, R.; Harnett, P.; Sharma, R.; Wain, G.; Ward, B.; Papadimos, D.; Crandon, A.; Cummings, M.; Horwood, K.; Obermair, A.; Perrin, L.; Wyld, D.; Nicklin, J.; Davy, M.; Oehler, M. K.; Hall, C.; Dodd, T.; Healy, T.; Pittman, K.; Henderson, D.; Miller, J.; Pierdes, J.; Blomfield, P.; Challis, D.; Mclntosh, R.; Parker, A.; Brown, B.; Rome, R.; Allen, D.; Grant, P.; Hyde, S.; Laurie, R.; Robbie, M.; Healy, D.; Jobling, T.; Manolitsas, T.; McNealage, J.; Rogers, P.; Susil, B.; Sumithran, E.; Simpson, I; Phillips, K.; Rischin, D.; Fox, S.; Johnson, D.; Lade, S.; Loughrey, M.; O'Callaghan, N.; Murray, W.; Waring, P.; Billson, V; Pyman, J.; Neesham, D.; Quinn, M.; Underhill, C.; Bell, R.; Ng, L. F.; Blum, R.; Ganju, V; Hammond, I; Leung, Y.; McCartney, A.; Buck, M.; Haviv, I; Purdie, D.; Whiteman, D.; Zeps, N.

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-04-1870

OAAI

Palbociclib synergizes with BRAF and MEK inhibitors in treatment naive melanoma but not after the development of BRAF inhibitor resistance

Palbociclib与BRAF和MEK抑制剂协同治疗幼稚黑色素瘤，但在BRAF抑制剂耐药性发展后没有

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2018-01-0359

OAAI

Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses