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收藏分享 收藏 Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells (vol 9, 250, 2018)
Page, Brent D. G.; Valerie, Nicholas C. K.; Wright, Roni H. G.; Wallner, Olov; Isaksson, Rebecka; Carter, Megan; Rudd, Sean G.; Loseva, Olga; Jemth, Ann-Sofie; Almlof, Ingrid; Font-Mateu, Jofre; Llona-Minguez, Sabin; Baranczewski, Pawel; Jeppsson, Fredrik; Homan, Evert; Almqvist, Helena; Axelsson, Hanna; Regmi, Shruti; Gustavsson, Anna-Lena; Lundback, Thomas; Scobie, Martin; Stromberg, Kia; Stenmark, Pal; Beato, Miguel; Helleday, Thomas 分享 收藏 Targeted NUDT5 inhibitors block hormone signaling in breast cancer cellsPage, Brent D. G.; Valerie, Nicholas C. K.; Wright, Roni H. G.; Wallner, Olov; Isaksson, Rebecka; Carter, Megan; Rudd, Sean G.; Loseva, Olga; Jemth, Ann-Sofie; Almlof, Ingrid; Font-Mateu, Jofre; Llona-Minguez, Sabin; Baranczewski, Pawel; Jeppsson, Fredrik; Homan, Evert; Almqvist, Helena; Axelsson, Hanna; Regmi, Shruti; Gustavsson, Anna-Lena; Lundback, Thomas; Scobie, Martin; Stromberg, Kia; Stenmark, Pal; Beato, Miguel; Helleday, Thomas 分享 收藏 分享 收藏 AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate KineticsEketjall, Susanna; Janson, Juliette; Kaspersson, Karin; Bogstedt, Anna; Jeppsson, Fredrik; Falting, Johanna; Haeberlein, Samantha Budd; Kugler, Alan R.; Alexander, Robert C.; Cebers, Gvido 分享 收藏 Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1Llona-Minguez, Sabin; Hoglund, Andreas; Jacques, Sylvain A.; Johanson, Lars; Calderon-Montano, Jose Manuel; Claesson, Magnus; Loseva, Olga; Valerie, Nicholas C. K.; Lundback, Thomas; Piedrafita, Javier; Maga, Giovanni; Crespan, Emmanuele; Meijer, Laurent; Moron, Estefania Burgos; Baranczewski, Pawel; Hagbjork, Ann-Louise; Svensson, Richard; Wiita, Elisee; Almlof, Ingrid; Visnes, Torkild; Jeppsson, Fredrik; Sigmundsson, Kristmundur; Jensen, Annika Jenmalm; Artursson, Per; Jemth, Ann-Sofie; Stenmark, Pal; Berglund, Ulrika Warpman; Scobie, Martin; Helleday, Thomas 分享 收藏 分享 收藏 分享 收藏 Core Refinement toward Permeable β-Secretase (BACE-1) Inhibitors with Low hERG ActivityGinman, Tobias; Viklund, Jenny; Malmstrom, Jonas; Blid, Jan; Emond, Rikard; Forsblom, Rickard; Johansson, Anh; Kers, Annika; Lake, Fredrik; Sehgelmeble, Fernando; Sterky, Karin J.; Bergh, Margareta; Lindgren, Anders; Johansson, Patrik; Jeppsson, Fredrik; Falting, Johanna; Gravenfors, Ylva; Rahm, Fredrik 分享 收藏 Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patientsForsberg, Anton; Jureus, Anders; Cselenyi, Zsolt; Eriksdotter, Maria; Freund-Levi, Yvonne; Jeppsson, Fredrik; Swahn, Britt-Marie; Sandell, Johan; Julin, Per; Schou, Magnus; Andersson, Jan; Johnstrom, Peter; Varnas, Katarina; Halldin, Christer; Farde, Lars; Svensson, Samuel 分享 收藏 分享 收藏 New Aminoimidazoles as β-Secretase (BACE-1) Inhibitors Showing Amyloid-β (Aβ) Lowering in Brain (vol 55, pg 9297, 2012)Gravenfors, Ylva; Viklund, Jenny; Blid, Jan; Ginman, Tobias; Arlstroem, Sofia K.; Kihlstroem, Jacob; Kolmodin, Karin; Lindstroem, Johan; von Berg, Stefan; von Kieseritzky, Fredrik; Bogar, Krisztian; Slivo, Can; Swahn, Britt-Marie; Olsson, Lise-Lotte; Johansson, Patrik; Eketjaell, Susanna; Faelting, Johanna; Jeppsson, Fredrik; Stroemberg, Kia; Janson, Juliette; Rahm, Fredrik 分享 收藏 Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer DiseaseJeppsson, Fredrik; Eketjall, Susanna; Janson, Juliette; Karlstrom, Sofia; Gustavsson, Susanne; Olsson, Lise-Lotte; Radesater, Ann-Cathrine; Ploeger, Bart; Cebers, Gvido; Kolmodin, Karin; Swahn, Britt-Marie; von Berg, Stefan; Bueters, Tjerk; Falting, Johanna 分享 收藏 New Aminoimidazoles as β-Secretase (BACE-1) Inhibitors Showing Amyloid-β (Aβ) Lowering in BrainGravenfors, Ylva; Viklund, Jenny; Blid, Jan; Ginman, Tobias; Karlstrom, Sofia; Kihlstrom, Jacob; Kolmodin, Karin; Lindstrom, Johan; von Berg, Stefan; von Kieseritzky, Fredrik; Slivo, Can; Swahn, Britt-Marie; Olsson, Lise-Lotte; Johansson, Patrik; Eketjall, Susanna; Falting, Johanna; Jeppsson, Fredrik; Stromberg, Kia; Janson, Juliette; Rahm, Fredrik 分享 收藏 Design and Synthesis of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors with in Vivo Brain Reduction of β-Amyloid PeptidesSwahn, Britt-Marie; Kolmodin, Karin; Karlstrom, Sofia; von Berg, Stefan; Soderman, Peter; Holenz, Jorg; Berg, Stefan; Lindstrom, Johan; Sundstrom, Marie; Turek, Dominika; Kihlstrom, Jacob; Slivo, Can; Andersson, Lars; Pyring, David; Rotticci, Didier; Ohberg, Liselotte; Kers, Annika; Bogar, Krisztian; von Kieseritzky, Fredrik; Bergh, Margareta; Olsson, Lise-Lotte; Janson, Juliette; Eketjall, Susanna; Georgievska, Biljana; Jeppsson, Fredrik; Falting, Johanna 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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