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Sarah Leary

Seattle Children's Research Institute
H指数:43
被引数:8,505

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Intracerebroventricular B7-H3-targeting chimeric antigen receptor T cells for non-pontine diffuse midline glioma and recurrent/refractory pediatric CNS tumors: A phase 1 trial

脑室内B7-H3靶向嵌合抗原受体T细胞治疗非脑桥弥漫性中线胶质瘤和复发/难治性儿童中枢神经系统肿瘤:一项1期临床试验

2026-07-250
PRE
Outcomes following radiotherapy for atypical teratoid/rhabdoid tumor in combination with surgery and intensive chemotherapy: A report from Children's Oncology Group study ACNS0333

典型畸胎样/横纹肌样瘤经手术和强化化疗联合放射治疗后结果:儿童肿瘤学组ACNS0333研究的报道

2026-01-010
OA
TIP-30. Molecularly-guided phase 2 umbrella trial for children and young adults with newly-diagnosed high-grade glioma (HGG) including diffuse intrinsic pontine glioma (DIPG): CONNECT TarGeT (Targeted pediatric HGG therapy) trial in progress

TIP-30. 分子引导的针对新诊断的高级别胶质瘤(HGG,包括弥漫性内生性脑桥胶质瘤(DIPG)的儿童及青少年患者的二期伞式临床试验:正在进行的CONNECT TarGeT(靶向儿科HGG疗法)试验。

2025-11-110
OA
Clinical stability following tovorafenib treatment in relapsed/refractory pediatric low-grade glioma: updated results from the phase 2 FIREFLY-1 trial

托伐拉芬治疗后复发/难治性儿童低级别胶质瘤的临床稳定性:更新来自2期FIREFLY-1试验的结果

2025-11-010
OAAI
An integrated analysis of three medulloblastoma clinical trials refines risk-stratification approaches for reducing toxicity and improving survival

对三项髓母细胞瘤临床试验的综合分析,优化了降低毒性和改善生存的风险分层方法

2025-11-010
OA
PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04

开创性四靶点CAR T细胞疗法在儿童中枢神经系统肿瘤中的应用——来自第一项人体I期临床试验BRAINCHILD-04的分析

2025-11-010
OAAI
Childhood cancer data initiative: expanded access to tumor molecular profiling for children, adolescents, and young adults
2025-09-018
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Locoregional infusion of EGFR806-CAR T cells for recurrent or refractory pediatric CNS tumors: Results of the completed BrainChild02 phase 1 clinical trial

Gust J,Cole BL,Ronsley R,Wilson AL,Seidel K,Wendler J,等. 局部区域灌注EGFR806-CAR T细胞治疗复发或难治性儿童中枢神经系统肿瘤:已完成brainChild02期1临床试验的结果. Neuro Oncol. (2025). doi: 10.1093/neuonc/noaf064

2025-06-016
PRE
The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial (vol 30, pg 207, 2024)

复发/难治性小儿低度神经胶质瘤中的II型RAF抑制剂tovorafenib: 2期FIREFLY-1试验 (第30卷,207页,2024)

2025-04-160
OA
Radiographic and visual response to the type II RAF inhibitor tovorafenib in children with relapsed/refractory optic pathway glioma in the FIREFLY-1 trial

在FIREFLY-1试验中,托瓦雷芬尼(tovorafenib)这种II型RAF抑制剂对复发性/难治性视神经通路胶质瘤患儿的放射学和视觉反应。

2024-12-190
PRE
Phase 2 trial of veliparib, local irradiation, and temozolomide in patients with newly diagnosed high-grade glioma: a Children's Oncology Group study

维利帕尼,局部放疗和替莫唑胺在新诊断的高级别神经胶质瘤患者中的2期试验: 儿童肿瘤学小组研究

2024-11-190
PRE