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N

Nicholas A. Vitanza

Seattle Children's Research Institute
H指数:33
被引数:4,102

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Intracerebroventricular B7-H3-targeting chimeric antigen receptor T cells for non-pontine diffuse midline glioma and recurrent/refractory pediatric CNS tumors: A phase 1 trial

脑室内B7-H3靶向嵌合抗原受体T细胞治疗非脑桥弥漫性中线胶质瘤和复发/难治性儿童中枢神经系统肿瘤：一项1期临床试验

Neuro-Oncology
IF13.4
2026-07-250
PRE
Rebecca Ronsley; Wenjun Huang; Ethan Rohlf; Kristy Seidel; Christopher Brown; Adam Beebe; Stephanie D Rawlings-Rhea; Catherine Lindgren; Tiffany Sad; Erin E Crotty; Sarah E S Leary; Alison Thomsen; Amy R Beckstrom; Susan L Holtzclaw; Corrine Hoeppner; Diana Hurst; Matthew MacQuivey; Hannah E Goldstein; Samuel R Browd; Jason S Hauptman; Amy Lee; Jeffrey G Ojemann; Jason N Wright; Catherine M Albert; Navin Pinto; Joshua A Gustafson; On Ho; Sowmya Pattabhi; Corinne Summers; Colleen Annesley; Jason N Wendler; Juliane Gust; Rebecca A Gardner; Julie R Park; Michael C Jensen; Nicholas A Vitanza
Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma

组合B7-H3 CAR T细胞与ONC206对弥漫性内生性脑桥胶质瘤的疗效研究

Neuro-Oncology
IF13.4
2026-03-011
PRE
Timpanaro, Andrea; Song, Edward Z.; Toumi, Ryma; Elena-Sanchez, Leonel; Piccand, Caroline; Nemec, Kelsey M.; Kordowski, Anja; Lau, Davina; Johnson, Scott; Winter, Lily; Rajendran, Ashmitha; Ronsley, Rebecca; Oda, Shannon K.; Gustafson, Joshua A.; Wendler, Jason P.; Koschmann, Carl; Evans, Myron; Pattwell, Siobhan; Jensen, Michael C.; Foster, Jessica B.; Dun, Matthew D.; Meechan, Michael; Biery, Matthew C.; Vitanza, Nicholas A.
A Cavernous Sinus Meningioma in a Child with Progressive Bilateral Visual Loss Ultimately Attributed to Unsuspected Optic Nerve Sheath Meningiomas

一名儿童患有海绵窦脑膜瘤，表现为进行性双侧视力丧失，最终归因于未预料的视神经鞘脑膜瘤

Case Reports in Ophthalmology
IF0.6
2026-01-010
OA
Wang, Debbie X.; Walker, Carson S.; Ahmedin, Yusra A.; Ohan, Masis A.; Vitanza, Nicholas A.; Ermoian, Ralph P.; Crotty, Erin E.; Francis, Courtney E.; Cabrera, Michelle T.
Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma

工程化CXCR3-A表达增强B7-H3靶向CAR T细胞的迁移和对弥漫性内生性脑桥胶质瘤的疗效

Nature Communications
IF15.7
2025-11-110
OAAI
Edward Z. Song; Andrea Timpanaro; Michael Meechan; Leonel Elena-Sanchez; Lucy Z. Li; Sophie Jamet; Davina S. Lau; Lily I. Winter; Matthew D. Dun; Jessica B. Foster; Myron K. Evans; Siobhan S. Pattwell; Vandana Kalia; Surojit Sarkar; Michael C. Jensen; Matthew C. Biery; Nicholas A. Vitanza
Leveraging the immunomodulatory effects of dordaviprone (ONC201) to induce long-term survival response in diffuse midline glioma patients and models

利用dordaviprone（ONC201）的免疫调节作用，在弥漫性中线胶质瘤患者和模型中诱导长期生存反应

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Savary, Clara; Persson, Mika L.; Jackson, Evangeline R.; Duchatel, Ryan J.; Vo, Tuan; Findlay, Izac J.; Douglas, Alicia M.; Bramberger, Liesl; De La Nava, Daniel; Thomas, Bryce C.; Mcewen, Holly P.; Beitaki, Tyrone S.; De La Fuente, Laura Rodriguez; Colino-Sanguino, Yolanda; Mora, Fatima Valdes; Larsen, Martin R.; Faridi, Pouya; Holst, Jeff; Mayall, Jemma; Kline, Cassie N.; Franson, Andrea T.; Venneti, Sriram; Hondermarck, Hubert; Horvat, Jay; Nixon, Brett; Cartaxo, Rodrigo; Nazarian, Javad; Hulleman, Esther; Mueller, Sabine; Vitanza, Nicholas A.; Koschmann, Carl; Alonso, Marta M.; Carvalheiro, Tiago Ferreira; Van Der Lugt, Jasper; Dun, Matthew D.
ENHANCING GENOME ANALYSIS WITH WHOLE PROTEOME PROFILING FOR IMPROVED THERAPEUTIC DECISION MAKING IN DIFFUSE MIDLINE GLIOMA

通过全蛋白质组分析增强基因组分析，以改善弥漫性中线胶质瘤的治疗决策制定

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Findlay, Izac; Staudt, Dilana; Duchatel, Ryan; Jackson, Evangeline; Persson, Mika; McEwen, Holly; Delevaux, Katherine; Smith, Nathan; Vitanza, Nicholas; Cain, Jason; Hansen, Mitchell; Alvaro, Frank; Jakobsen, Lene; Larsen, Martin; Savary, Clara; Waszak, Sebastian; Dun, Matthew
PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04

开创性四靶点CAR T细胞疗法在儿童中枢神经系统肿瘤中的应用——来自第一项人体I期临床试验BRAINCHILD-04的分析

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Ronsley, Rebecca; Seidel, Kristy; Narayanaswamy, Prabha; Pattabhi, Sowmya; Wendler, Jason; Rawlings-Rhea, Stephanie; Huang, Wenjun; Crotty, Erin; Leary, Sarah; Lee, Amy; Park, Julie; Jensen, Michael; Vitanza, Nicholas
Tumor inflammation-associated neurotoxicity in children with diffuse intrinsic pontine glioma receiving B7-H3-targeting CAR T cells on BrainChild-03

儿童弥漫性内生性脑桥胶质瘤患者在接受B7-H3靶向CAR T细胞治疗（BrainChild-03）时出现的肿瘤炎症相关神经毒性

NEURO-ONCOLOGY PRACTICE
IF2.5
2025-09-011
PRE
Ronsley, Rebecca; Choe, Michelle; Wright, Jason; Seidel, Kristy; Lee, Amy; Wendler, Jason; Annesley, Colleen; Jensen, Michael C.; Park, Julie R.; Vitanza, Nicholas A.; Gust, Juliane
Locoregional infusion of EGFR806-CAR T cells for recurrent or refractory pediatric CNS tumors: Results of the completed BrainChild02 phase 1 clinical trial

Gust J，Cole BL，Ronsley R，Wilson AL，Seidel K，Wendler J，等. 局部区域灌注EGFR806-CAR T细胞治疗复发或难治性儿童中枢神经系统肿瘤：已完成brainChild02期1临床试验的结果. Neuro Oncol. (2025). doi: 10.1093/neuonc/noaf064

NEURO-ONCOLOGY
IF13.4
2025-06-016
PRE
Gust, Juliane; Cole, Bonnie L.; Ronsley, Rebecca; Wilson, Ashley L.; Seidel, Kristy; Wendler, Jason; Pattabhi, Sowmya; Brown, Christopher; Rawlings-Rhea, Stephanie D.; Shtanukhina, Nadezhda; Browd, Samuel R.; Hauptman, Jason S.; Lee, Amy; Ojemann, Jeffrey G.; Crotty, Erin E.; Leary, Sarah E. S.; Perez, Francisco A.; Wright, Jason N.; Albert, Catherine M.; Pinto, Navin; Gardner, Rebecca A.; Vitanza, Nicholas A.; Jensen, Michael C.; Park, Julie R.
PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE INITIAL PATIENTS TREATED ON THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Ronsley, Rebecca; Seidel, Kristy; Narayanaswamy, Prabha; Pattabhi, Sowmya; Wendler, Jason; Ho, On; Rawlings-Rhea, Stephanie; Gust, Juliane; Huang, Wenjun; Crotty, Erin; Leary, Sarah; Runco, Daniel; Hauptman, Jason; Gardner, Rebecca; Park, Julie; Annesley, Colleen; Jensen, Michael; Vitanza, Nicholas
An international study presenting a federated learning AI platform for pediatric brain tumors
NATURE COMMUNICATIONS
IF15.7
2024-09-020
OAAI
Lee, Edward H.; Han, Michelle; Wright, Jason; Kuwabara, Michael; Mevorach, Jacob; Fu, Gang; Choudhury, Olivia; Ratan, Ujjwal; Zhang, Michael; Wagner, Matthias W.; Goetti, Robert; Toescu, Sebastian; Perreault, Sebastien; Dogan, Hakan; Altinmakas, Emre; Mohammadzadeh, Maryam; Szymanski, Kathryn A.; Campen, Cynthia J.; Lai, Hollie; Eghbal, Azam; Radmanesh, Alireza; Mankad, Kshitij; Aquilina, Kristian; Said, Mourad; Vossough, Arastoo; Oztekin, Ozgur; Ertl-Wagner, Birgit; Poussaint, Tina; Thompson, Eric M.; Ho, Chang Y.; Jaju, Alok; Curran, John; Ramaswamy, Vijay; Cheshier, Samuel H.; Grant, Gerald A.; Wong, S. Simon; Moseley, Michael E.; Lober, Robert M.; Wilms, Mattias; Forkert, Nils D.; Vitanza, Nicholas A.; Miller, Jeffrey H.; Prolo, Laura M.; Yeom, Kristen W.
INTRAVENTRICULAR B7-H3 CAR T CELLS FOR DIFFUSE INTRINSIC PONTINE GLIOMA: SAFETY AND EFFICACY REPORT FROM THE COMPLETED PHASE 1 TRIAL BRAINCHILD-03

脑室内B7-H3 CAR T细胞治疗弥漫性内在性脑桥胶质瘤: 已完成的1期试验BRAINCHILD-03的安全性和有效性报告

NEURO-ONCOLOGY
IF13.4
2024-06-181
OAAI
Vitanza, Nicholas A.; Ronsley, Rebecca; Huang, Wenjuan; Seidel, Kristy; Thomsen, Alison; Gust, Juliane; Hauptman, Jason; Choe, Michlle; Crotty, Erin; Leary, Sarah; Gustafson, Joshua A.; Gardner, Rebecca A.; Pattabhi, Sowmya; Wendler, Jason; Ho, On; Annesley, Colleen; Park, Julie R.; Jensen, Michael C.
DRD2 ANTAGONISM RESCUES IMMUNE-TUMOR SURVEILLANCE, WARMING THE TUMOR IMMUNE MICROENVIRONMENT OF DIFFUSE MIDLINE GLIOMA MODELS
NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
Persson, Mika L.; Jackson, Evangeline R.; Duchatel, Ryan J.; de la Nava, Daniel; Thomas, Bryce C.; Savary, Clara; Mcewen, Holly P.; Beitaki, Tyrone S.; Kearney, Padraic S.; Findlay, Izac J.; Douglas, Alicia M.; Larsen, Martin R.; Faridi, Pouya; Holst, Jeff; Mayall, Jemma; Hondermarck, Hubert; Horvat, Jay; Nixon, Brett; Cartaxo, Rodrigo T.; Nazarian, Javad; Hulleman, Esther; Mueller, Sabine; Vitanza, Nicholas A.; Koshmann, Carl; Alonso, Marta M.; Carvalheiro, Tiago; van der Lugt, Jasper; Dun, Matthew D.

研究方向

暂未获取到该数据
M
Michael C. Jensen
H 指数:80论文数:630被引数:3.3万
M
Matthew D. Dun
H 指数:41论文数:327被引数:5,242
R
Rebecca Ronsley
H 指数:17论文数:110被引数:1,105
J
Juliane Gust
H 指数:23论文数:82被引数:5,554
S
Sarah Leary
H 指数:43论文数:287被引数:8,505
J
Julie R. Park
H 指数:61论文数:378被引数:1.4万
R
Rebecca Gardner
H 指数:31论文数:145被引数:1.0万
C
Carl Koschmann
H 指数:37论文数:480被引数:4,528
J
Jason N. Wright
H 指数:17论文数:80被引数:1,401
J
Jason S. Hauptman
H 指数:26论文数:176被引数:3,117