Michael C. Jensen - Publications, H-index & Citations

Michael C. Jensen

Seattle Children's Research Institute

80H指数

629论文数

3.3W被引数

收录论文 116

发表时间

Genome-wide CRISPRa screens identify modulators of CAR T survival across diverse tumor cytokine milieus 全基因组CRISPRa筛选鉴定了在多样化肿瘤细胞因子微环境中调节CAR T细胞存活的调控因子

Molecular Therapy Nucleic Acids

IF6.1

2026-09-28

OAAI

Benjamin C. Curtis; Cailyn H. Spurrell; Lindsay Flint; Aalton M. Lande; Marissa Leonardi; James M. Rosser; Tavie Parker; Tiffanie Chai; Ardizon Valdez; Ryma Toumi; Nat Murren; Michael Fitzgerald; Jasmin Martinez-Reyes; Finn Watt; Christopher P. Saxby; Corinne Summers; Kamila S. Gwiazda; Michael C.V. Jensen; Shannon K. Oda

Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma 组合B7-H3 CAR T细胞与ONC206对弥漫性内生性脑桥胶质瘤的疗效研究

Neuro-Oncology

IF13.4

2026-03-01

PREAI

Timpanaro, Andrea; Song, Edward Z.; Toumi, Ryma; Elena-Sanchez, Leonel; Piccand, Caroline; Nemec, Kelsey M.; Kordowski, Anja; Lau, Davina; Johnson, Scott; Winter, Lily; Rajendran, Ashmitha; Ronsley, Rebecca; Oda, Shannon K.; Gustafson, Joshua A.; Wendler, Jason P.; Koschmann, Carl; Evans, Myron; Pattwell, Siobhan; Jensen, Michael C.; Foster, Jessica B.; Dun, Matthew D.; Meechan, Michael; Biery, Matthew C.; Vitanza, Nicholas A.

Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma 工程化CXCR3-A表达增强B7-H3靶向CAR T细胞的迁移和对弥漫性内生性脑桥胶质瘤的疗效

Nature Communications

IF15.7

2025-11-11

OAAI

Edward Z. Song; Andrea Timpanaro; Michael Meechan; Leonel Elena-Sanchez; Lucy Z. Li; Sophie Jamet; Davina S. Lau; Lily I. Winter; Matthew D. Dun; Jessica B. Foster; Myron K. Evans; Siobhan S. Pattwell; Vandana Kalia; Surojit Sarkar; Michael C. Jensen; Matthew C. Biery; Nicholas A. Vitanza

PROTEIN CHANGES IN SERIAL CSF SAMPLES REFLECT CAR ACTIVITY, TOXICITY AND DISEASE RESPONSE IN PATIENTS WITH DIPG TREATED ON THE BRAINCHILD03 TRIAL 连续CSF样本中的蛋白质变化反映了接受BRAINCHILD03试验治疗的DIPG患者的CAR活性、毒性及疾病反应。

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Ronsley, Rebecca; Chowdhury, Shrabanti; Abdollahi, Kourosh; Ivey, Richard; Whitaker, Jeffrey; Wendler, Jason; Jensen, Michael; Wang, Pei; Vitanza, Nicholas; Paulovich, Amanda

PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04 开创性四靶点CAR T细胞疗法在儿童中枢神经系统肿瘤中的应用——来自第一项人体I期临床试验BRAINCHILD-04的分析

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Ronsley, Rebecca; Seidel, Kristy; Narayanaswamy, Prabha; Pattabhi, Sowmya; Wendler, Jason; Rawlings-Rhea, Stephanie; Huang, Wenjun; Crotty, Erin; Leary, Sarah; Lee, Amy; Park, Julie; Jensen, Michael; Vitanza, Nicholas

Tumor inflammation-associated neurotoxicity in children with diffuse intrinsic pontine glioma receiving B7-H3-targeting CAR T cells on BrainChild-03 儿童弥漫性内生性脑桥胶质瘤患者在接受B7-H3靶向CAR T细胞治疗（BrainChild-03）时出现的肿瘤炎症相关神经毒性

NEURO-ONCOLOGY PRACTICE

IF2.5

2025-09-01

PREAI

Ronsley, Rebecca; Choe, Michelle; Wright, Jason; Seidel, Kristy; Lee, Amy; Wendler, Jason; Annesley, Colleen; Jensen, Michael C.; Park, Julie R.; Vitanza, Nicholas A.; Gust, Juliane

Efficient and Traceless Aptamer-Based Serial Selection of Naïve and Early Memory CD8 T Cells for CAR T Cell Therapy 基于适体的幼稚和早期记忆CD8 T细胞的高效无痕串联筛选用于CAR T细胞治疗

Advanced Healthcare Materials

IF9.6

2025-08-29

PREAI

Abe Y. Wu; Emmeline L. Cheng; Nataly Kacherovsky; Abigail Marking; Arie Lin-Goldstein; Clinton M. Heinze; Stephen J. Salipante; Michael C. Jensen; Suzie H. Pun

Locoregional infusion of EGFR806-CAR T cells for recurrent or refractory pediatric CNS tumors: Results of the completed BrainChild02 phase 1 clinical trial Gust J，Cole BL，Ronsley R，Wilson AL，Seidel K，Wendler J，等. 局部区域灌注EGFR806-CAR T细胞治疗复发或难治性儿童中枢神经系统肿瘤：已完成brainChild02期1临床试验的结果. Neuro Oncol. (2025). doi: 10.1093/neuonc/noaf064

NEURO-ONCOLOGY

IF13.4

2025-06-01

PREAI

Gust, Juliane; Cole, Bonnie L.; Ronsley, Rebecca; Wilson, Ashley L.; Seidel, Kristy; Wendler, Jason; Pattabhi, Sowmya; Brown, Christopher; Rawlings-Rhea, Stephanie D.; Shtanukhina, Nadezhda; Browd, Samuel R.; Hauptman, Jason S.; Lee, Amy; Ojemann, Jeffrey G.; Crotty, Erin E.; Leary, Sarah E. S.; Perez, Francisco A.; Wright, Jason N.; Albert, Catherine M.; Pinto, Navin; Gardner, Rebecca A.; Vitanza, Nicholas A.; Jensen, Michael C.; Park, Julie R.

Low Peripheral Blood Counts and Elevated Proinflammatory Cytokines Signal a Poor CD19 Chimeric Antigen Receptor T-cell Response in Acute Lymphoblastic Leukemia 外周血计数低和升高的促炎细胞因子预示急性淋巴细胞白血病中CD19嵌合抗原受体T细胞反应不良

Transplantation and Cellular Therapy

IF4.4

2025-05-20

OAAI

Katelyn Burleigh; Kelly G. Stratton; Jenny L. Smith; Michael C. Jensen; Cameron J. Turtle; Camille Keenan; Colleen Annesley; Corinne Summers; Bobbie-Jo Webb-Robertson; Alexandre V. Hirayama; Rebecca A. Gardner; Heather H. Gustafson

Outcomes of PLAT-02 and PLAT-03: evaluating CD19 CAR T-cell therapy and CD19-expressing T-APC support in pediatric B-ALL PLAT-02和PLAT-03的研究结果：评估CD19 CAR T细胞疗法及CD19表达T-APC支持在儿童B-ALL中的应用

Blood

IF23.1

2025-04-17

PREAI

Colleen Annesley; Kristy Seidel; Qian Wu; Corinne Summers; Alan S. Wayne; Michael A. Pulsipher; Anurag K. Agrawal; Chris T. Brown; Stephanie Mgebroff; Catherine Lindgren; Stephanie Rawlings-Rhea; Wenjun Huang; Ashley L. Wilson; Michael C. Jensen; Julie R. Park; Rebecca A. Gardner

In Situ Bioconjugation of Synthetic Peptides onto Universal Chimeric Antigen Receptor T Cells for Targeted Cancer Immunotherapies 在位生物缀合合成肽至通用嵌合抗原受体T细胞，用于靶向癌症免疫疗法

ACS NANO

IF16

2025-01-27

PREAI

Cardle, II; Scherer, DR; Jensen, MC; Pun, SH; Sellers, DL

DNA Aptamer-Polymer Conjugates for Selective Targeting of Integrin α4β1+ T-Lineage Cancers DNA适配体-聚合物偶联物用于选择性靶向整合素α4β1+ T系肿瘤

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2025-01-09

PREAI

Cardle, II; Raman, J; Nguyen, DC; Wang, T; Wu, AY; Sellers, DL; Pichon, TJ; Cheng, EL; Kacherovsky, N; Salipante, SJ; Jensen, MC; Pun, SH

PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE INITIAL PATIENTS TREATED ON THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Ronsley, Rebecca; Seidel, Kristy; Narayanaswamy, Prabha; Pattabhi, Sowmya; Wendler, Jason; Ho, On; Rawlings-Rhea, Stephanie; Gust, Juliane; Huang, Wenjun; Crotty, Erin; Leary, Sarah; Runco, Daniel; Hauptman, Jason; Gardner, Rebecca; Park, Julie; Annesley, Colleen; Jensen, Michael; Vitanza, Nicholas

INTRAVENTRICULAR B7-H3 CAR T CELLS FOR DIFFUSE INTRINSIC PONTINE GLIOMA: SAFETY AND EFFICACY REPORT FROM THE COMPLETED PHASE 1 TRIAL BRAINCHILD-03 脑室内B7-H3 CAR T细胞治疗弥漫性内在性脑桥胶质瘤: 已完成的1期试验BRAINCHILD-03的安全性和有效性报告

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Vitanza, Nicholas A.; Ronsley, Rebecca; Huang, Wenjuan; Seidel, Kristy; Thomsen, Alison; Gust, Juliane; Hauptman, Jason; Choe, Michlle; Crotty, Erin; Leary, Sarah; Gustafson, Joshua A.; Gardner, Rebecca A.; Pattabhi, Sowmya; Wendler, Jason; Ho, On; Annesley, Colleen; Park, Julie R.; Jensen, Michael C.

PRECLINICAL EFFICACY OF B7-H3 CAR T CELLS IN COMBINATION WITH ONC206

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Timpanaro, Andrea; Song, Edward; Biery, Matthew C.; Lau, Davina; Meechan, Michael; Elena-Sanchez, Leonel; Vo, Linh Thuy; Gustafson, Joshua; Koschmann, Carl; Dun, Matthew D.; Foster, Jessica B.; Jensen, Michael C.; Vitanza, Nicholas A.

PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE INITIAL PATIENTS TREATED ON THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Ronsley, Rebecca; Choe, Michelle; Seidel, Kristy; Narayanaswamy, Prabha; Pattabhi, Sowmya; Wendler, Jason; Ho, On; Rawlings-Rhea, Stephanie; Gust, Juliane; Huang, Wenjun; Crotty, Erin; Leary, Sarah; Hauptman, Jason; Albert, Catherine M.; Gardner, Rebecca A.; Park, Julie R.; Annesley, Colleen; Jensen, Michael C.; Vitanza, Nicholas A.

Getting what you pay for: impact of copayments on physical therapy and opioid initiation, timing, and continuation for newly diagnosed low back pain

SPINE JOURNAL

IF4.7

2024-06-01

PREAI

Jin, Michael C.; Jensen, Michael; Guinle, Maria Isabel Barros; Ren, Alexander; Zhou, Zeyi; Zygourakis, Corinna C.; Desai, Atman M.; Veeravagu, Anand; Ratliff, John K.

Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing 药物调节的CD33-targeted CAR T细胞使用临床优化的雷帕霉素剂量控制AML

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-03-19

OAAI

Appelbaum, Jacob; Price, April E.; Oda, Kaori; Zhang, Joy; Leung, Wai-Hang; Tampella, Giacomo; Xia, Dong; So, Pauline P. L.; Hilton, Sarah K.; Evandy, Claudya; Sarkar, Semanti; Martin, Unja; Krostag, Anne-Rachel; Leonardi, Marissa; Zak, Daniel E.; Logan, Rachael; Lewis, Paula; Franke-Welch, Secil; Ngwenyama, Njabulo; Fitzgerald, Michael; Tulberg, Niklas; Rawlings-Rhea, Stephanie; Gardner, Rebecca A.; Jones, Kyle; Sanabria, Angelica; Crago, William; Timmer, John; Hollands, Andrew; Eckelman, Brendan; Bilic, Sanela; Woodworth, Jim; Lamble, Adam; Gregory, Philip D.; Jarjour, Jordan; Pogson, Mark; Gustafson, Joshua A.; Astrakhan, Alexander; Jensen, Michael C.

Differential protein-protein interactions underlie signaling mediated by the TCR and a 4-1BB domain-containing CAR

SCIENCE SIGNALING

IF6.6

2024-03-05

OAAI

Ritmeester-Loy, Samuel A.; Draper, Isabella H.; Bueter, Eric C.; Lautz, Jonathan D.; Zhang-Wong, Yue; Gustafson, Joshua A.; Wilson, Ashley L.; Lin, Chenwei; Gafken, Philip R.; Jensen, Michael C.; Orentas, Rimas; Smith, Stephen E. P.

A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia 干细胞表观基因组与儿童急性淋巴细胞白血病对CD19 CAR T细胞的原发性无反应有关

BLOOD ADVANCES

IF7.1

2023-08-08

OAAI

Masih, Katherine E.; Gardner, Rebecca A.; Chou, Hsien-Chao; Abdelmaksoud, Abdalla; Song, Young K.; Mariani, Luca; Gangalapudi, Vineela; Gryder, Berkley E.; Wilson, Ashley L.; Adebola, Serifat O.; Stanton, Benjamin Z.; Wang, Chaoyu; Milewski, David; Kim, Yong Yean; Tian, Meijie; Cheuk, Adam Tai -Chi; Wen, Xinyu; Zhang, Yue; Altan-Bonnet, Gregoire; Kelly, Michael C.; Wei, Jun S.; Bulyk, Martha L.; Jensen, Michael C.; Orentas, Rimas J.; Khan, Javed

研究方向