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Alfonso De Simone

University of Naples

45H指数
201论文数
9.1K被引数
收录论文 102
发表时间
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Corrigendum to “Protein Kinase A Phosphorylates a Conformationally High-Energy State of Raf Kinase Inhibitory Protein” [J. Mol. Biol. 437(23) (2025) 169466]勘误：“蛋白激酶A磷酸化Raf激酶抑制蛋白的一种构象高能状态”【J. Mol. Biol. 437(23) (2025) 169466】
errJournal of Molecular Biology
IF4.5
err2026-09-18
err0
PREAI
errCristina Olivieri; Carmen Biancaniello; V.S. Manu; Matthew Walters; Larry Masterson; Marsha Rich Rosner; Alfonso De Simone; Gianluigi Veglia
err分享
err收藏
A novel dual-target approach for Parkinson’s disease therapy by the novel immunomodulator 3-monothiopomalidomide新型免疫调节剂3-单硫代帕莫利Domide通过新型双靶点方法治疗帕金森病
errnpj Parkinsons Disease
IF8.2
err2026-09-01
err0
errOAAI
errMaria Francesca Palmas; Khosro Aminzadeh; Matteo Runfola; Pathik Parekh; Clara Porcedda; David Tweedie; Luca Casula; Maria Cristina Cardia; Jacopo Marongiu; Michela Etzi; Francesco Lai; Marcello Serra; Valeria Crippa; Augusta Pisanu; Valeria Sogos; Alfonso De Simone; Dong Seok Kim; Nigel H. Greig; Anna R. Carta
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Integrative blood transcriptomics identifies U1-snRNP gene repression and miRNA–mRNA regulatory hubs in pre-clinical Parkinson’s disease整合血液转录组学鉴定了临床前期帕金森病中U1-snRNP基因的抑制和miRNA–mRNA调控中心
errnpj Parkinsons Disease
IF8.2
err2026-08-11
err0
errOAAI
errDavide D’Angelo; Alfonso De Simone; Nunzio D’Agostino
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α-Synuclein aggregation landscape from phase separation to neurotoxic intermediates从相分离到神经毒性中间体的α-突触核蛋白聚集景观
errFEBS Letters
IF3
err2026-07-01
err0
errOAAI
errSilvia Arino; Giuliana Fusco; Alfonso De Simone
err分享
err收藏
Development of broadly cross-reactive mRNA COVID-19 vaccines based on trimeric RBDs of Spike protein and NSP12 to overcome immune imprinting基于刺突蛋白三聚体RBD和NSP12的广谱交叉反应性mRNA COVID-19疫苗的开发，以克服免疫印迹现象
errMolecular Therapy Nucleic Acids
IF6.1
err2026-03-25
err0
errOAAI
errArianna De Chiara; Caterina Giachino; Maria Franca Pirillo; Andrea Campanile; Emilio Pellino; Alessandra Gallinaro; Guendalina Froechlich; Chiara Falce; Annagiulia Scognamiglio; Simone Totaro; Maria Vittoria Liguori; Rosa Peltrini; Alfonso De Simone; Stefania Capone; Zoppoli Pietro; Donatella Negri; Andrea Cara; Alfredo Nicosia; Emanuele Sasso
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err收藏
Integrating NMR Restraints into Coarse-Grained Simulations: Toward Accurate Conformational Ensembles of Complex Protein Systems将NMR约束整合到粗粒化模拟中：朝向复杂蛋白质系统的准确构象集合
errJournal of the American Chemical Society
IF15.6
err2026-03-19
err0
errOAAI
errMina Cullen; Carmen Biancaniello; Katerina Taškova; Vedran Miletić; Davide Mercadante; Alfonso De Simone
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Aggregation and membrane activity of mutant A30P alpha-synuclein on mitochondrial membranes突变体A30Pα-突触核蛋白在线粒体膜上的聚集及膜活性
errInternational Journal of Biological Macromolecules
IF8.5
err2026-03-17
err0
errOAAI
errMaja Herrera; Adam El Saghir; Silvia Mansueto; Stephanie Ghio; Giuliana Fusco; Alfonso De Simone; Neville Vassallo
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err收藏
Energy Landscape Analysis of Membrane Proteins Using NMR-Based Hybrid Restraint Potentials基于NMR的混合约束势能的膜蛋白能量景观分析
errJournal of Chemical Theory and Computation
IF5.5
err2026-03-12
err0
errOAAI
errDiksha Dewan; Yifei Wang; Alfonso De Simone; David J. Wales
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err收藏
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates细胞朊蛋白和钙离子触发α-突触核蛋白聚集体的神经毒性
errCell & Bioscience
IF0
err2025-12-09
err0
errOAAI
errAlessandra Bigi; Andrea Carlotta Conti; Liliana Napolitano; Giuliana Fusco; Alfonso De Simone; Fabrizio Chiti; Roberta Cascella; Cristina Cecchi
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Retinal alterations resemble brain pathology in a rat model of Parkinson’s disease induced by intranigral infusion of α-synuclein oligomers视网膜的改变与帕金森病大鼠模型中由黑质内注射α-突触核蛋白寡聚体诱导的脑病理相似。
errCell Death Discovery
IF7
err2025-11-28
err0
errOAAI
errChiara Burgaletto; Anna Flavia Cantone; Maria Francesca Palmas; Chiara Bianca Maria Platania; Giulia Di Benedetto; Gabriella Gaudio; Cristina Barbagallo; Marco Ragusa; Claudio Bucolo; Nunzio Vicario; Ezio Carboni; Alfonso De Simone; Renato Bernardini; Anna R. Carta; Giuseppina Cantarella
err分享
err收藏
Structure and Dynamics of the Misfolding Intermediate in the Pathogenic T183A Prion Protein Mutant错误折叠中间体在致病性T183A朊病毒蛋白突变体中的结构与动力学
errJournal of Chemical Theory and Computation
IF5.5
err2025-10-04
err0
errOAAI
errCarmen Biancaniello; Alessandro Emendato; Alfonso De Simone
err分享
err收藏
Protein Kinase A Phosphorylates a Conformationally High-Energy State of Raf Kinase Inhibitory Protein蛋白激酶A磷酸化构象高能状态的Raf激酶抑制蛋白
errJournal of Molecular Biology
IF4.5
err2025-09-26
err0
PREAI
errCristina Olivieri; Carmen Biancaniello; V.S. Manu; Matthew Walters; Larry Masterson; Marsha Rich Rosner; Alfonso De Simone; Gianluigi Veglia
err分享
err收藏
Deep-Learning Driven Identification of Novel Antimicrobial Peptides深度学习驱动的抗菌肽新型鉴定
errChemistry – A European Journal
IF0
err2025-08-13
err0
errOAAI
errDr. Silvia Arino; Dr. Gianmattia Sgueglia; Dr. Linda Leone; Dr. Rosario Oliva; Prof. Pompea Del Vecchio; Dr. Gerald Larrouy-Maumus; Prof. Angela Lombardi; Prof. Alfonso De Simone; Prof. Flavia Nastri
err分享
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The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism腺苷酸环化酶调节物作为6-nitrodopamine在人类诱导多能干细胞（hiPSC）来源的心肌细胞中的潜在受体的鉴定及其在心脏变力性中的相关性
errFrontiers in Pharmacology
IF4.8
err2025-08-12
err0
errOAAI
errIrene Cipollone†; Vittoria Monaco†; José Britto-Júnior; Antonio Tiago Lima; Edson Antunes; Andre Sampaio Pupo; Ilaria Iacobucci; Flora Cozzolino; Maria Monti; Silvia Parisi; Giuseppina Divisato; Emanuela Cascone; Alfonso De Simone; Angela Corvino; Ferdinando Fiorino; Francesco Frecentese; Vincenzo Santagada; Beatrice Severino; Rosa Sparaco; Pierfrancesco Cinque; Stefania Vertuccio; Giuseppe Caliendo; Gilberto De Nucci
err分享
err收藏
Catalytic Nanomaterials by Conjugation of an Artificial Heme-Peroxidase to Amyloid Fibrils
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2024-08-14
err0
PREAI
errEsposito, Alessandra; Leone, Linda; De Simone, Alfonso; Fusco, Giuliana; Nastri, Flavia; Lombardi, Angela
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err收藏
Under the Influence of Water: Molecular Recognition of Organic Hydrophilic Molecules in Water with a Prismarene Host Driven by Hydration Effects
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2024-07-17
err2
PREAI
errDel Regno, Rocco; Della Sala, Paolo; Santonoceta, Giuseppina D. G.; Neri, Placido; De Rosa, Margherita; Talotta, Carmen; Sgarlata, Carmelo; De Simone, Alfonso; Gaeta, Carmine
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α-Synuclein and Mitochondria: Probing the Dynamics of Disordered Membrane-protein Regions Using Solid-State Nuclear Magnetic ResonanceΑ-突触核蛋白和线粒体: 使用固态核磁共振探测无序膜蛋白区域的动力学
errJACS AU
IF8.7
err2024-05-28
err1
errOAAI
errGallo, Angelo; Mansueto, Silvia; Emendato, Alessandro; Fusco, Giuliana; De Simone, Alfonso
err分享
err收藏
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein CondensatesΑ-突触核蛋白缩合物中间原纤维的结构-毒性关系
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-04-03
err6
errOAAI
errChen, Serene W.; Barritt, Joseph D.; Cascella, Roberta; Bigi, Alessandra; Cecchi, Cristina; Banchelli, Martina; Gallo, Angelo; Jarvis, James A.; Chiti, Fabrizio; Dobson, Christopher M.; Fusco, Giuliana; De Simone, Alfonso
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MetalHawk: Enhanced Classification of Metal Coordination Geometries by Artificial Neural Networks
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-11-13
err4
errOAAI
errSgueglia, Gianmattia; Vrettas, Michail D.; Chino, Marco; De Simone, Alfonso; Lombardi, Angela
err分享
err收藏
Editorial: Oligomers in amyloid-associated diseases-structural properties and toxicity社论: 淀粉样蛋白相关疾病中的寡聚体-结构特性和毒性
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2023-06-21
err1
errOAAI
errVassallo, Neville; Ongeri, Sandrine; De Simone, Alfonso
err分享
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研究方向

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合作学者
合作期刊
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A
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H 指数: 123 · 论文数: 881
P
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H 指数: 120 · 论文数: 698
M
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