Charles D. Papageorgiou - Publications, H-index & Citations

Charles D. Papageorgiou

takeda development center americas, inc.

22H指数

70论文数

1.8K被引数

收录论文 35

发表时间

Hydrogenation Process Development in a Data-Rich Environment 数据丰富环境下的加氢工艺开发

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2026-06-30

PREAI

Peter Sagmeister; Kensaku Matsunami; Giovanni Aprile; Darren A. Whitaker; Mohammed Janoudi; Thomas Toupy; Adrian Ramirez Galilea; Neda Nazemifard; Charles D. Papageorgiou; Aparajith Bhaskar; John Mack; Richard D. Braatz; Allan S. Myerson

A systematic model development framework for pharmaceutical batch crystallization processes using an iterative model-based experimental design approach 一种用于制药批次结晶过程的系统化模型开发框架，采用迭代模型导向的实验设计方法

Chemical Engineering Science

IF4.3

2026-03-29

PREAI

Hemalatha Kilari; Yung-Shun Kang; Neda Nazemifard; C.Benjamin Renner; Yihui Yang; Charles D. Papageorgiou; Zoltan K. Nagy

Digital design of crystallization processes using statistical machine learning 结晶过程的数字设计：基于统计机器学习

Computers & Chemical Engineering

IF3.9

2025-12-10

PREAI

Yash Barhate; Yung Shun Kang; Neda Nazemifard; C. Benjamin Renner; Yihui Yang; Charles Papageorgiou; Zoltan K. Nagy

Particle engineering of a needle-like active pharmaceutical ingredient into size controlled agglomerates: Part I. Process scalability and development 将针状活性药物成分进行颗粒工程化处理以形成尺寸可控的聚集体：第一部分。工艺放大与开发

International Journal of Pharmaceutics

IF5.2

2025-11-06

PREAI

Bilal Ahmed; Vishal Raval; Mark McGowan; Yihui Yang; Marianne Langston; Charles D. Papageorgiou; Kenneth Smith

FMEnets: Flow, material, and energy networks for non-ideal plug flow reactor design FMEnets: 流体、物料和能量网络在非理想活塞流反应器设计中的应用

Chemical Engineering Science

IF4.3

2025-08-24

PREAI

Chenxi Wu; Juan Diego Toscano; Khemraj Shukla; Yingjie Chen; Ali Shahmohammadi; Edward Raymond; Thomas Toupy; Neda Nazemifard; Charles Papageorgiou; George Em Karniadakis

Deep Reinforcement Learning-Based Self-Optimization of Flow Chemistry 基于深度强化学习的流 chemistry 自我优化

ACS ENGINEERING AU

IF5.1

2025-05-13

OAAI

Yewale, A; Yang, YH; Nazemifard, N; Papageorgiou, CD; Rielly, CD; Benyahia, B

Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)

NATURE COMMUNICATIONS

IF15.7

2023-03-01

OAAI

Zhang, Qihang; Gamekkanda, Janaka C.; Pandit, Ajinkya; Tang, Wenlong; Papageorgiou, Charles; Mitchell, Chris; Yang, Yihui; Schwaerzler, Michael; Oyetunde, Tolutola; Braatz, Richard D.; Myerson, Allan S.; Barbastathis, George

Machine Learning-Derived Correlations for Scale-Up and Technology Transfer of Primary Nucleation Kinetics

CRYSTAL GROWTH & DESIGN

IF3.4

2023-01-18

OAAI

Yerdelen, Stephanie; Yang, Yihui; Quon, Justin L.; Papageorgiou, Charles D.; Mitchell, Chris; Houson, Ian; Sefcik, Jan; ter Horst, Joop H.; Florence, Alastair J.; Brown, Cameron J.

Monitoring and digital design of the cooling crystallization of a high-aspect ratio anticancer drug using a two-dimensional population balance model 使用二维种群平衡模型对高纵横比抗癌药物的冷却结晶进行监测和数字化设计

CHEMICAL ENGINEERING SCIENCE

IF4.3

2022-08-01

PREAI

Szilagyi, Botond; Eren, Ayse; Quon, Justin L.; Papageorgiou, Charles D.; Nagy, Zoltan K.

Use of Wet Milling Combined with Temperature Cycling to Minimize Crystal Agglomeration in a Sequential Antisolvent-Cooling Crystallization

CRYSTAL GROWTH & DESIGN

IF3.4

2022-07-19

OAAI

Sun, Zhuang; Quon, Justin L.; Papageorgiou, Charles D.; Benyahia, Brahim; Rielly, Chris D.

Infrared temperature measurements and DEM simulations of heat transfer in a bladed mixer

AICHE JOURNAL

IF4

2022-02-25

PREAI

Hartmanshenn, Clara; Chaksmithanont, Prin; Leung, Carlin; Ghare, Digvijay, V; Chakraborty, Nabaneeta; Patel, Sagar; Halota, Madeline; Khinast, Johannes G.; Papageorgiou, Charles D.; Mitchell, Chris; Quon, Justin L.; Glasser, Benjamin J.

Digital Design of the Crystallization of an Active Pharmaceutical Ingredient Using a Population Balance Model with a Novel Size Dependent Growth Rate Expression. From Development of a Digital Twin to In Silico Optimization and Experimental Validation 使用具有新型尺寸依赖性生长速率表达的群体平衡模型对活性药物成分的结晶进行数字设计。从数字孪生体的开发到计算机优化和实验验证

CRYSTAL GROWTH & DESIGN

IF3.4

2021-12-20

PREAI

Szilagyi, Botond; Eren, Ayse; Quon, Justin L.; Papageorgiou, Charles D.; Nagy, Zoltan K.

Investigation of Wet Milling and Indirect Ultrasound as Means for Controlling Nucleation in the Continuous Crystallization of an Active Pharmaceutical Ingredient

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2021-09-01

OAAI

Yang, Yihui; Ahmed, Bilal; Mitchell, Christopher; Quon, Justin L.; Siddique, Humera; Houson, Ian; Florence, Alastair J.; Papageorgiou, Charles D.

Experimental Investigation of an Integrated Crystallization and Wet-Milling System with Temperature Cycling to Control the Size and Aspect Ratio of Needle-Shaped Pharmaceutical Crystals

CRYSTAL GROWTH & DESIGN

IF3.4

2021-05-24

PREAI

Eren, Ayse; Szilagyi, Botond; Quon, Justin L.; Papageorgiou, Charles D.; Nagy, Zoltan K.

Application of Model-Free and Model-Based Quality-by-Control (QbC) for the Efficient Design of Pharmaceutical Crystallization Processes

CRYSTAL GROWTH & DESIGN

IF3.4

2020-04-15

PREAI

Szilagyi, Botond; Eren, Ayse; Quon, Justin L.; Papageorgiou, Charles D.; Nagy, Zoltan K.

Development of a Novel Screening Methodology for the Assessment of the Risk of Particle Size Attrition during Agitated Drying

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2020-01-23

PREAI

Papageorgiou, Charles D.; Mitchell, Christopher; Quon, Justin L.; Langston, Marianne; Borg, Suzanna; Hicks, Frederick; Ende, David; Breault, Mark

Heat transfer of dry granular materials in a bladed mixer: Effect of thermal properties and agitation rate

AICHE JOURNAL

IF4

2019-11-27

PREAI

Hartmanshenn, Clara; Khinast, Johannes G.; Papageorgiou, Charles D.; Mitchell, Chris; Quon, Justin; Glasser, Benjamin J.

Development and Scale-Up of a Crystallization Process To Improve an API's Physiochemical and Bulk Powder Properties

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2018-01-10

PREAI

Durak, Landon; Kennedy, Miriam; Langston, Marianne; Mitchell, Christopher; Morris, Gary; Perlman, Michael E.; Wendl, Kaitlyn; Hicks, Frederick; Papageorgiou, Charles D.

Development and Scale-up of a Flow Chemistry Lithiation-Borylation Route to a Key Boronic Acid Starting Material

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2017-04-06

PREAI

Usutani, Hirotsugu; Nihei, Takashi; Papageorgiou, Charles D.; Cork, David G.

The Pharmaceutical Drying Unit Operation: An Industry Perspective on Advancing the Science and Development Approach for Scale-Up and Technology Transfer

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2017-03-09

PREAI

Conder, Edward W.; Cosbie, Andrew S.; Gaertner, John; Hicks, William; Huggins, Seth; MacLeod, Claire S.; Remy, Brenda; Yang, Bing-Shiou; Engstrom, Joshua D.; Lamberto, David J.; Papageorgiou, Charles D.

研究方向