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Paul R. Carlier

university of illinois chicago hospital

39H指数
231论文数
4.9K被引数
收录论文 74
发表时间
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Dihydroorotate dehydrogenase inhibitors are potent antiviral agents against henipaviruses and arenaviruses二氢乳清酸脱氢酶抑制剂是针对亨尼帕病毒和沙粒病毒的强效抗病毒剂
errAntiviral Research
IF4
err2026-08-01
err0
PREAI
errLi, Yuanyuan; Ma, Jing; Bott, Ryan; McMullan, Laura K.; Lo, Michael K.; Chatterjee, Payel; Flint, Mike; Spengler, Jessica R.; Kunz, Kevin A.; Argade, Malaika D.; Ratia, Kiira; Rong, Rong; Carlier, Paul R.; Rong, Lijun
err分享
err收藏
Identification of an Orally Efficacious Imidazo[4,5-c]pyridine-6-Carboxamide Antimalarial with a High Barrier to Resistance一种具有高耐药性屏障的口服有效咪唑[4,5-c]吡啶-6-甲酰胺类抗疟药鉴定
errJournal of Medicinal Chemistry
IF6.8
err2026-04-01
err0
PREAI
errZhou, Bo; Do Amaral, Leticia S.; Bremers, Emily K.; Haney, Reagan S.; Wardlaw, Lyric A.; Merino, Emilio F.; Li, Yuexin; Buchanan, Mairi; Baud, Delphine; Brand, Stephen; Lee, Marcus C. S.; Kelly, Jane X.; Totrov, Maxim; Cassera, Maria B.; Carlier, Paul R.
err分享
err收藏
Discovery and Optimization of First-in-Class Furopyrimidine-Based Inhibitors of Henipaviruses
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2026-01-01
err0
PREAI
errGaisina, Irina N.; Argade, Malaika D.; Bott, Ryan; Bradley, Sean P.; Tomorowicz, Lukasz; Alvarez, Mario; Galvan Achi, Jazmin M.; Cross, Robert W.; Borisevich, Viktoriya; O'Toole, Rachel; Amaya, Moushimi; Zielinski, Christian A.; Gaisin, Arsen M.; Nikolic, Dejan; Carlier, Paul R.; Anantpadma, Manu; Moore, Terry W.; Broder, Christopher C.; Geisbert, Thomas W.; Peet, Norton P.; Rong, Lijun
err分享
err收藏
Development of a comparative high-throughput screening platform for identifying glioblastoma subtype specific inhibitors开发一个用于识别胶质母细胞瘤亚型特异性抑制剂的比较高通量筛选平台
errCell Insight
IF0
err2025-12-01
err0
errOAAI
errWang, Zilai; Zhang, Pin; Ratia, Kiira M.; Daher, Ahmad; Zhao, Zongmin; Carlier, Paul R.; Jiang, Yuwei; Rong, Lijun
err分享
err收藏
Solvent-, enzyme-, and structural-dependence of phenyl-substituted methyl carbamate inhibition of acetylcholinesterase酚基取代甲基氨基甲酸酯对乙酰胆碱酯酶抑制作用的溶剂依赖性、酶依赖性和结构依赖性
errInsect Biochemistry and Molecular Biology
IF3.7
err2025-08-23
err0
PREAI
errDaniel R. Swale; Paul R. Carlier; Maxim Totrov; Jeffrey R. Bloomquist
err分享
err收藏
Benzo-ring modification on Malaria Box hit MMV008138: effects on antimalarial potency and microsomal stability疟疾药箱（Malaria Box）中的命中化合物MMV008138的苯环修饰：对抗疟活性和微粒体稳定性的影响
errRSC Med. Chem.
IF3.6
err2025-08-16
err0
errOAAI
errMaryam Ghavami; Haibo Li; Lixuan Liu; Joshua H. Butler; Sha Ding; Grant J. Butschek; Reagan S. Haney; R. McAlister Council-Troche; R. Justin Grams; Emilio Merino; Jennifer M Davis; Maxim Totrov; Maria B. Cassera; Paul R Carlier
err分享
err收藏
Recombinant Pichinde reporter virus as a safe and suitable surrogate for high-throughput antiviral screening against highly pathogenic arenaviruses重组Pichinde报告病毒作为高通量抗病毒筛选中高致病性汉坦病毒的安全且合适的替代品
errANTIVIRAL RESEARCH
IF4
err2025-04-01
err0
errOAAI
errSacramento, Carolina Q.; Bott, Ryan; Huang, Qinfeng; Eaton, Brett; Postnikova, Elena; Sabir, Ahmad J.; Argade, Malaika D.; Ratia, Kiira; Anantpadma, Manu; Carlier, Paul R.; Ly, Hinh; Liang, Yuying; Rong, Lijun
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err收藏
Mosquito mutations F290V and F331W expressed in acetylcholinesterase of the sand fly Phlebotomus papatasi (Scopoli): biochemical properties and inhibitor sensitivity
errPARASITES & VECTORS
IF3.5
err2025-02-18
err0
errOAAI
errTemeyer, Kevin B.; Tong, Fan; Schlechte, Kristie G.; Chen, Qiao-hong; Carlier, Paul R.; de Leon, Adalberto A. Perez; Bloomquist, Jeffrey R.
err分享
err收藏
Stereospecific Resistance to N2-Acyl Tetrahydro-β-carboline Antimalarials Is Mediated by a PfMDR1 Mutation That Confers Collateral Drug Sensitivity
errACS INFECTIOUS DISEASES
IF3.8
err2025-01-14
err0
errOAAI
errBremers, Emily K.; Butler, Joshua H.; Do Amaral, Leticia S.; Merino, Emilio F.; Almolhim, Hanan; Zhou, Bo; Baptista, Rodrigo P.; Totrov, Maxim; Carlier, Paul R.; Cassera, Maria Belen
err分享
err收藏
β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling
errACS INFECTIOUS DISEASES
IF3.8
err2024-10-28
err1
PREAI
errMathew, Jopaul; Zhou, Bo; Haney, Reagan S.; Kunz, Kevin A.; Do Amaral, Leticia S.; Chowdhury, Rudraneel Roy; Butler, Joshua H.; Li, Haibo; Chakraborty, Amarraj J.; Tabassum, Anika; Bremers, Emily K.; Merino, Emilio F.; Coyle, Rachael; Lee, Marcus C. S.; Baud, Delphine; Brand, Stephen; Totrov, Maxim; Cassera, Maria Belen; Carlier, Paul R.
err分享
err收藏
G Protein 12 Alpha Subunit Covalent Binding To Alpha-snap And Its Potential Role In Von Willebrand Factor Secretion
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-05-01
err0
PREAI
errRusu, Luiza; Bloem, Laura J.; Chen, Hui; Lee, Hyun; Ratia, Kiira M.; Jayathilaka, Lasanthi; Carlier, Paul R.; Minshall, Richard D.
err分享
err收藏
Substituted salicylic acid analogs offer improved potency against multidrug-resistant Neisseria gonorrhoeae and good selectivity against commensal vaginal bacteria
errSCIENTIFIC REPORTS
IF3.9
err2023-09-02
err4
errOAAI
errAlmolhim, Hanan; Elhassanny, Ahmed E. M.; Abutaleb, Nader S.; Abdelsattar, Abdallah S.; Seleem, Mohamed N.; Carlier, Paul R.
err分享
err收藏
Characterizing the Mechanism of Resistance of PRC1590 Using Known Antimalarials
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errDo Amaral, Leticia; Bremers, Emily; Butler, Joshua; Merino, Emilio; Baptista, Rodrigo; Almolhim, Hanan; Totrov, Max; Carlier, Paul; Cassera, Maria
err分享
err收藏
Discovery of Two Inhibitors of the Type IV Pilus Assembly ATPase PilB as Potential Antivirulence Compounds
errMICROBIOLOGY SPECTRUM
IF3.8
err2022-12-21
err11
errOAAI
errDye, Keane J.; Vogelaar, Nancy J.; O'Hara, Megan; Sobrado, Pablo; Santos, Webster; Carlier, Paul R.; Yang, Zhaomin
err分享
err收藏
Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials In Vitro
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2022-02-24
err9
errOAAI
errAlmolhim, Hanan; Ding, Sha; Butler, Joshua H.; Bremers, Emily K.; Butschek, Grant J.; Slebodnick, Carla; Merino, Emilio F.; Rizopoulos, Zaira; Totrov, Maxim; Cassera, Maria B.; Carlier, Paul R.
err分享
err收藏
Malaria Box-Inspired Discovery of N-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2022-02-23
err10
errOAAI
errMathew, Jopaul; Ding, Sha; Kunz, Kevin A.; Stacy, Emily E.; Butler, Joshua H.; Haney, Reagan S.; Merino, Emilio F.; Butschek, Grant J.; Rizopoulos, Zaira; Totrov, Maxim; Cassera, Maria B.; Carlier, Paul R.
err分享
err收藏
Testing new compounds for efficacy against Varroa destructor and safety to honey bees (Apis mellifera)测试新化合物对Varroa destructor的功效和对蜜蜂 (Apis mellifera) 的安全性
errPEST MANAGEMENT SCIENCE
IF3.8
err2021-09-14
err7
PREAI
errJack, Cameron J.; Kleckner, Kaylin; Demares, Fabien; Rault, Leslie C.; Anderson, Troy D.; Carlier, Paul R.; Bloomquist, Jeffrey R.; Ellis, James D.
err分享
err收藏
Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand To Treat Alzheimer's Disease
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-06-22
err9
PREAI
errXuan, Zhenquan; Gu, Xinmei; Yan, Sicheng; Xie, Yanfei; Zhou, Yiying; Zhang, Hui; Jin, Haibo; Hu, Shengquan; Mak, Marvin S. H.; Zhou, Dongsheng; Tsim, Karl Wah Keung; Carlier, Paul R.; Han, Yifan; Cui, Wei
err分享
err收藏
Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2018-11-07
err17
errOAAI
errChen, Huixin; Wu, Xiang; Gu, Xinmei; Zhou, Yiying; Ye, Luying; Zhang, Ke; Pan, Hanbo; Wang, Jialing; Wei, Hua; Zhu, Binbin; Naman, C. Benjamin; Mak, Shinghung; Carlier, Paul R.; Cui, Wei; Han, Yifan
err分享
err收藏
Biological Studies and Target Engagement of the 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1R,3S)-MMV008138 and Analogs
errACS INFECTIOUS DISEASES
IF3.8
err2017-10-26
err36
errOAAI
errGhavami, Maryam; Merino, Emilio F.; Yao, Zhong-Ke; Elahi, Rubayet; Simpson, Morgan E.; Fernandez-Murga, Maria L.; Butler, Joshua H.; Casasanta, Michael A.; Krai, Priscilla M.; Totrov, Maxim M.; Slade, Daniel J.; Carlier, Paul R.; Cassera, Maria Belen
err分享
err收藏

研究方向

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