logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
E

Elisa Gibson

Structural Genomics Consortium
H指数:10
被引数:666

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Structure-based discovery of inhibitors of Mac1 domain of nonstructural protein-3 of SARS-CoV-2 by machine learning-augmented screening of chemical space

基于机器学习增强的化学空间筛选，发现SARS-CoV-2非结构蛋白-3的Mac1结构域抑制剂的结构方法

Scientific Reports
IF3.9
2026-08-030
OA
Fuqiang Ban; Rahul Ravichandran; Galen J. Correy; Oleksandra Herasymenko; Madhushika Silva; Suzanne Ackloo; Albina Bolotokova; Irene Chau; Elisa Gibson; Rachel Harding; Ashley Hutchinson; Peter Loppnau; James S. Fraser; Matthieu Schapira; Artem Cherkasov; Francesco Gentile
CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2

缓存挑战 #3: 以SARS-CoV-2的Nsp3宏域为目标

Journal of Chemical Information and Modeling
IF5.3
2026-01-210
OAAI
Oleksandra Herasymenko; Madhushika Silva; Galen J. Correy; Abd Al-Aziz A. Abu-Saleh; Suzanne Ackloo; Cheryl Arrowsmith; Alan Ashworth; Fuqiang Ban; Hartmut Beck; Kevin P. Bishop; Hugo J. Bohórquez; Albina Bolotokova; Marko Breznik; Irene Chau; Yu Chen; Artem Cherkasov; Wim Dehaen; Dennis Della Corte; Katrin Denzinger; Niklas P. Doering; Kristina Edfeldt; Aled Edwards; Darren Fayne; Francesco Gentile; Elisa Gibson; Ozan Gokdemir; Anders Gunnarsson; Judith Günther; John J. Irwin; Jan Halborg Jensen; Rachel J. Harding; Alexander Hillisch; Laurent Hoffer; Anders Hogner; Ashley Hutchinson; Shubhangi Kandwal; Andrea Karlova; Kushal Koirala; Sergei Kotelnikov; Dima Kozakov; Juyong Lee; Soowon Lee; Uta Lessel; Sijie Liu; Xuefeng Liu; Peter Loppnau; Jens Meiler; Rocco Moretti; Yurii S. Moroz; Charuvaka Muvva; Tudor I. Oprea; Brooks Paige; Amit Pandit; Keunwan Park; Gennady Poda; Mykola V. Protopopov; Vera Pütter; Rahul Ravichandran; Didier Rognan; Edina Rosta; Yogesh Sabnis; Thomas Scott; Almagul Seitova; Purshotam Sharma; François Sindt; Minghu Song; Casper Steinmann; Rick Stevens; Valerij Talagayev; Valentyna V. Tararina; Olga Tarkhanova; Damon Tingey; John F. Trant; Dakota Treleaven; Alexander Tropsha; Patrick Walters; Jude Wells; Yvonne Westermaier; Gerhard Wolber; Lars Wortmann; Shuangjia Zheng; James S. Fraser; Matthieu Schapira
Enantioselective protein affinity selection mass spectrometry (E-ASMS)

手性蛋白质亲和选择质谱法 (E-ASMS)

Nature Communications
IF15.7
2025-12-170
OAAI
Xiaoyun Wang; Jianxian Sun; Shabbir Ahmad; Diwen Yang; Fengling Li; U. Hang Chan; Hong Zeng; Conrad V. Simoben; Stuart R. Green; Madhushika Silva; Scott Houliston; Aiping Dong; Albina Bolotokova; Elisa Gibson; Maria Kutera; Pegah Ghiabi; Ivan Kondratov; Tetiana Matviyuk; Alexander Chuprina; Danai Mavridi; Christopher Lenz; Andreas C. Joerger; Benjamin D. Brown; Richard B. Heath; Wyatt W. Yue; Lucy K. Robbie; Tyler S. Beyett; Susanne Müller; Stefan Knapp; Dafydd R. Owen; Rachel Harding; Matthieu Schapira; Peter J. Brown; Vijayaratnam Santhakumar; Suzanne Ackloo; Cheryl H. Arrowsmith; Aled M. Edwards; Hui Peng; Levon Halabelian
Nucleosome context regulates chromatin reader preference

核小体环境调控染色质读码器偏好

NUCLEIC ACIDS RESEARCH
IF13.1
2025-11-110
PRE
Marunde, Matthew R.; Popova, Irina K.; Hall, Nathan W.; Vaidya, Anup; Bone, James R.; Boone, Brandon A.; Brown, Peter J.; Ezell, Ryan J.; Firestone, Tessa M.; Fuchs, Harrison A.; Gibson, Elisa; Gillespie, Zachary B.; Gloor, Susan L.; Hickman, Allison R.; Howard, Sarah A.; Husby, Natalia Ledo; Hsiung, Victoria T.; Johnstone, Andrea L.; Khan, Laiba F.; Krajewski, Krzysztof; Lee, Alexander S.; Mcanarney, Eileen T.; Maier, Keith E.; Maryanski, Danielle N.; McCuiston, Jamie L.; Noll, Kelsey E.; Novitzky, Katherine; Patteson, Emily F.; Rodriguez, Keli L.; Sanchez, Julio C.; Schachner, Luis F.; Smith, Catherine E.; Sun, Lu; Taylor, Hailey F.; Watson, Rachel; Willis, Hannah E.; Musselman, Catherine A.; Venters, Bryan J.; Cheek, Marcus A.; Meiners, Matthew J.; Sun, Zu-Wen; Kelleher, Neil L.; Cowles, Martis W.; Weinzapfel, Ellen N.; Keogh, Michael-Christopher; Burg, Jonathan M.
Enabling Open Machine Learning of Deoxyribonucleic Acid-Encoded Library Selections to Accelerate the Discovery of Small Molecule Protein Binders

通过开放机器学习实现脱氧核糖核酸编码库选择，以加速小分子蛋白质结合物的发现

Journal of Medicinal Chemistry
IF6.8
2025-10-060
OAAI
James Wellnitz; Shabbir Ahmad; Nabin Bagale; Xuemin Cheng; Jermiah Joseph; Hong Zeng; Albina Bolotokova; Aiping Dong; Shaghayegh Reza; Pegah Ghiabi; Elisa Gibson; Guiping Tu; Xianyang Li; Jian Liu; Dengfeng Dou; Jin Li; Timothy L. Foley; Anthony R. Harris; Jacquelyn L. Klug-McLeod; Jisun Lee; Zsofia Lengyel-Zhand; Justin I. Montgomery; Sylvie Sakata; Jinzhi Zhang; Hongyao Zhu; Dafydd R. Owen; Rachel J. Harding; Aled M. Edwards; Benjamin Haibe-Kains; Levon Halabelian; Alexander Tropsha; Rafael M. Couñago
CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

CACHE挑战赛#2：靶向SARS-CoV-2解旋酶Nsp13的RNA位点

Journal of Chemical Information and Modeling
IF5.3
2025-06-200
PRE
Oleksandra Herasymenko; Madhushika Silva; Abd Al-Aziz A. Abu-Saleh; Ayaz Ahmad; Jesus Alvarado-Huayhuaz; Oscar E. A. Arce; Roly J. Armstrong; Cheryl Arrowsmith; Kelly E. Bachta; Hartmut Beck; Denes Berta; Mateusz K. Bieniek; Vincent Blay; Albina Bolotokova; Philip E. Bourne; Marko Breznik; Peter J. Brown; Aaron D. G. Campbell; Emanuele Carosati; Irene Chau; Daniel J. Cole; Ben Cree; Wim Dehaen; Katrin Denzinger; Karina dos Santos Machado; Ian Dunn; Prasannavenkatesh Durai; Kristina Edfeldt; Aled Edwards; Darren Fayne; Daniel Felfoldi; Kallie Friston; Pegah Ghiabi; Elisa Gibson; Judith Günther; Anders Gunnarsson; Alexander Hillisch; Douglas R. Houston; Jan Halborg Jensen; Rachel J. Harding; Kate S. Harris; Laurent Hoffer; Anders Hogner; Joshua T. Horton; Scott Houliston; Judd F. Hultquist; Ashley Hutchinson; John J. Irwin; Marko Jukič; Shubhangi Kandwal; Andrea Karlova; Vittorio L. Katis; Ryan P. Kich; Dmitri Kireev; David Koes; Nicole L. Inniss; Uta Lessel; Sijie Liu; Peter Loppnau; Wei Lu; Sam Martino; Miles McGibbon; Jens Meiler; Akhila Mettu; Sam Money-Kyrle; Rocco Moretti; Yurii S. Moroz; Charuvaka Muvva; Joseph A. Newman; Leon Obendorf; Brooks Paige; Amit Pandit; Keunwan Park; Sumera Perveen; Rachael Pirie; Gennady Poda; Mykola Protopopov; Vera Pütter; Federico Ricci; Natalie J. Roper; Edina Rosta; Margarita Rzhetskaya; Yogesh Sabnis; Karla J. F. Satchell; Frederico Schmitt Kremer; Thomas Scott; Almagul Seitova; Casper Steinmann; Valerij Talagayev; Olga O. Tarkhanova; Natalie J. Tatum; Dakota Treleaven; Adriano Velasque Werhli; W. Patrick Walters; Xiaowen Wang; Jude Wells; Geoffrey Wells; Yvonne Westermaier; Gerhard Wolber; Lars Wortmann; Jixian Zhang; Zheng Zhao; Shuangjia Zheng; Matthieu Schapira
Active Learning-Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on In Silico Ligand-Binding Affinities

基于模拟配体结合亲和力的主动学习引导的富含亮氨酸重复激酶2 WDR结构域命中优化

JOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
2025-05-260
OA
Gusev, Filipp; Gutkin, Evgeny; Gentile, Francesco; Ban, Fuqiang; Koby, S. Benjamin; Li, Fengling; Chau, Irene; Ackloo, Suzanne; Arrowsmith, Cheryl H.; Bolotokova, Albina; Ghiabi, Pegah; Gibson, Elisa; Halabelian, Levon; Houliston, Scott; Harding, Rachel J.; Hutchinson, Ashley; Loppnau, Peter; Perveen, Sumera; Seitova, Almagul; Zeng, Hong; Schapira, Matthieu; Isayev, Olexandr; Kurnikova, Maria G.
Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1

由FRASE-bot在CACHE Challenge #1中鉴定的靶向LRRK2 WD40重复结构域的功能性活性调节剂

CHEMICAL SCIENCE
IF7.4
2025-01-010
OA
Mettu, Akhila; Glavatskikh, Marta; Wang, Xiaowen; Ordonez, Antonio Jesus Lara; Li, Fengling; Chau, Irene; Ackloo, Suzanne; Arrowsmith, Cheryl; Bolotokova, Albina; Ghiabi, Pegah; Gibson, Elisa; Halabelian, Levon; Houliston, Scott; Harding, Rachel J.; Hutchinson, Ashley; Loppnau, Peter; Perveen, Sumera; Seitova, Almagul; Zeng, Hong; Schapira, Matthieu; Taymans, Jean-Marc; Kireev, Dmitri
CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein
JOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
2024-11-054
OA
Li, Fengling; Ackloo, Suzanne; Arrowsmith, Cheryl H.; Ban, Fuqiang; Barden, Christopher J.; Beck, Hartmut; Beranek, Jan; Berenger, Francois; Bolotokova, Albina; Bret, Guillaume; Breznik, Marko; Carosati, Emanuele; Chau, Irene; Chen, Yu; Cherkasov, Artem; Della Corte, Dennis; Denzinger, Katrin; Dong, Aiping; Draga, Sorin; Dunn, Ian; Edfeldt, Kristina; Edwards, Aled; Eguida, Merveille; Eisenhuth, Paul; Friedrich, Lukas; Fuerll, Alexander; Gardiner, Spencer S.; Gentile, Francesco; Ghiabi, Pegah; Gibson, Elisa; Glavatskikh, Marta; Gorgulla, Christoph; Guenther, Judith; Gunnarsson, Anders; Gusev, Filipp; Gutkin, Evgeny; Halabelian, Levon; Harding, Rachel J.; Hillisch, Alexander; Hoffer, Laurent; Hogner, Anders; Houliston, Scott; Irwin, John J.; Isayev, Olexandr; Ivanova, Aleksandra; Jacquemard, Celien; Jarrett, Austin J.; Jensen, Jan H.; Kireev, Dmitri; Kleber, Julian; Koby, S. Benjamin; Koes, David; Kumar, Ashutosh; Kurnikova, Maria G.; Kutlushina, Alina; Lessel, Uta; Liessmann, Fabian; Liu, Sijie; Lu, Wei; Meiler, Jens; Mettu, Akhila; Minibaeva, Guzel; Moretti, Rocco; Morris, Connor J.; Narangoda, Chamali; Noonan, Theresa; Obendorf, Leon; Pach, Szymon; Pandit, Amit; Perveen, Sumera; Poda, Gennady; Polishchuk, Pavel; Puls, Kristina; Puetter, Vera; Rognan, Didier; Roskams-Edris, Dylan; Schindler, Christina; Sindt, Francois; Spiwok, Vojtech; Steinmann, Casper; Stevens, Rick L.; Talagayev, Valerij; Tingey, Damon; Vu, Oanh; Walters, W. Patrick; Wang, Xiaowen; Wang, Zhenyu; Wolber, Gerhard; Wolf, Clemens Alexander; Wortmann, Lars; Zeng, Hong; Zepeda, Carlos A.; Zhang, Kam Y. J.; Zhang, Jixian; Zheng, Shuangjia; Schapira, Matthieu
A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-11-040
OAAI
Ackloo, Suzanne; Li, Fengling; Szewczyk, Magda; Seitova, Almagul; Loppnau, Peter; Zeng, Hong; Xu, Jin; Ahmad, Shabbir; Arnautova, Yelena A.; Baghaie, A. J.; Beldar, Serap; Bolotokova, Albina; Centrella, Paolo A.; Chau, Irene; Clark, Matthew A.; Cuozzo, John W.; Dehghani-Tafti, Saba; Disch, Jeremy S.; Dong, Aiping; Dumas, Antoine; Feng, Jianwen A.; Ghiabi, Pegah; Gibson, Elisa; Gilmer, Justin; Goldman, Brian; Green, Stuart R.; Guie, Marie-Aude; Guilinger, John P.; Harms, Nathan; Herasymenko, Oleksandra; Houliston, Scott; Hutchinson, Ashley; Kearnes, Steven; Keefe, Anthony D.; Kimani, Serah W.; Kramer, Trevor; Kutera, Maria; Kwak, Haejin A.; Lento, Cristina; Li, Yanjun; Liu, Jenny; Loup, Joachim; Machado, Raquel A. C.; Mulhern, Christopher J.; Perveen, Sumera; Righetto, Germanna L.; Riley, Patrick; Shrestha, Suman; Sigel, Eric A.; Silva, Madhushika; Sintchak, Michael D.; Slakman, Belinda L.; Taylor, Rhys D.; Thompson, James; Torng, Wen; Underkoffler, Carl; von Rechenberg, Moritz; Walsh, Ryan T.; Watson, Ian; Wilson, Derek J.; Wolf, Esther; Yadav, Manisha; Yazdi, Aliakbar K.; Zhang, Junyi; Zhang, Ying; Santhakumar, Vijayaratnam; Edwards, Aled M.; Barsyte-Lovejoy, Dalia; Schapira, Matthieu; Brown, Peter J.; Halabelian, Levon; Arrowsmith, Cheryl H.
Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2
JOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
2024-06-252
OA
Eguida, Merveille; Bret, Guillaume; Sindt, Francois; Li, Fengling; Chau, Irene; Ackloo, Suzanne; Arrowsmith, Cheryl; Bolotokova, Albina; Ghiabi, Pegah; Gibson, Elisa; Halabelian, Levon; Houliston, Scott; Harding, Rachel J.; Hutchinson, Ashley; Loppnau, Peter; Perveen, Sumera; Seitova, Almagul; Zeng, Hong; Schapira, Matthieu; Rognan, Didier
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2

发现一种有效且选择性的靶向NSD2降解剂，用于还原H3K36me2

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2023-03-2825
PRE
Hanley, Ronan P.; Nie, David Y.; Tabor, John R.; Li, Fengling; Sobh, Amin; Xu, Chenxi; Barker, Natalie K.; Dilworth, David; Hajian, Taraneh; Gibson, Elisa; Szewczyk, Magdalena M.; Brown, Peter J.; Barsyte-Lovejoy, Dalia; Herring, Laura E.; Wang, Gang Greg; Licht, Jonathan D.; Vedadi, Masoud; Arrowsmith, Cheryl H.; James, Lindsey I.
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

靶向PWWP结构域的化学探针改变了NSD2核仁定位

NATURE CHEMICAL BIOLOGY
IF13.7
2021-11-1553
OA
Dilworth, David; Hanley, Ronan P.; de Freitas, Renato Ferreira; Allali-Hassani, Abdellah; Zhou, Mengqi; Mehta, Naimee; Marunde, Matthew R.; Ackloo, Suzanne; Machado, Raquel Arminda Carvalho; Yazdi, Aliakbar Khalili; Owens, Dominic D. G.; Vu, Victoria; Nie, David Y.; Alqazzaz, Mona; Marcon, Edyta; Li, Fengling; Chau, Irene; Bolotokova, Albina; Qin, Su; Lei, Ming; Liu, Yanli; Szewczyk, Magdalena M.; Dong, Aiping; Kazemzadeh, Sina; Abramyan, Tigran; Popova, Irina K.; Hall, Nathan W.; Meiners, Matthew J.; Cheek, Marcus A.; Gibson, Elisa; Kireev, Dmitri; Greenblatt, Jack F.; Keogh, Michael-C; Min, Jinrong; Brown, Peter J.; Vedadi, Masoud; Arrowsmith, Cheryl H.; Barsyte-Lovejoy, Dalia; James, Lindsey, I; Schapira, Matthieu
Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-02-0129
OA
de Freitas, Renato Ferreira; Liu, Yanli; Szewczyk, Magdalena M.; Mehta, Naimee; Li, Fengling; McLeod, David; Zepeda-Velazquez, Carlos; Dilworth, David; Hanley, Ronan P.; Gibson, Elisa; Brown, Peter J.; Al-Awar, Rima; James, Lindsey, I; Arrowsmith, Cheryl H.; Barsyte-Lovejoy, Dalia; Min, Jinrong; Vedadi, Masoud; Schapira, Matthieu; Allali-Hassani, Abdellah
Critical Assessments of Computational Hit-finding Experiments Challenge #4: Targeting the Tyrosine Kinase Binding Domain of the E3 Ligase Casitas B-Lineage Lymphoma Proto-Oncogene B, an Immuno-Oncology Target

对计算命中筛选实验的严格评估：挑战 #4：靶向E3泛素连接酶Casitas B淋巴瘤原癌基因B的酪氨酸激酶结合域，一个免疫肿瘤学靶点

Journal of Chemical Information and Modeling
IF5.3
0
PRE
Madhushika Silva; Oleksandra Herasymenko; Abd Al-Aziz A. Abu-Saleh; Suzanne Ackloo; Rima Al-awar; Cheryl H. Arrowsmith; Ryota Ashizawa; David J. Bearss; Hartmut Beck; Kevin P. Bishop; Vincent Blay; Hugo J. Bohórquez; Albina Bolotokova; Duanhua Cao; Irene Chau; Lin Chen; Sandro Cosconati; Wim Dehaen; Kristina Edfeldt; Aled M. Edwards; Elisa Gibson; Gediminas Gumbis; Christoph Gorgulla; Anders Gunnarsson; Rachel J. Harding; Laurent Hoffer; Anders Hogner; Scott Houliston; Douglas R. Houston; Oleksii Hrabovskyi; John J. Irwin; Diane Joseph-McCarthy; Andrea Karlova; Sergei Kotelnikov; Dima Kozakov; Uta Lessel; Peter Loppnau; Wei Lu; Kyle Medley; Miles McGibbon; Yurii Moroz; Charuvaka Muvva; Benito Natale; Boyang Ni; Eva Nittinger; Tudor I. Oprea; Brooks Paige; Keunwan Park; Gennady Poda; Konstantin I. Popov; Mykola V. Protopopov; Vera Pütter; Edina Rosta; Michele Roggia; Yogesh Sabnis; Christopher Secker; Olha Semenenko; Conrad V. Simoben; Olga O. Tarkhanova; Dakota Treleaven; Alexander Tropsha; David Uehling; Hariprasad Vankayalapati; Jude Wells; James Wellnitz; Yvonne Westermaier; Lars Wortmann; Jixian Zhang; Shuangjia Zheng; Yuchen Zhou; Sara Ziadat; Levon Halabelian; Matthieu Schapira

研究方向

暂未获取到该数据
M
Matthieu Schapira
H 指数:60论文数:414被引数:1.7万
S
Suzanne Ackloo
H 指数:24论文数:122被引数:1,949
R
Rachel Harding
H 指数:18论文数:561被引数:1,023
A
Albina Bolotokova
H 指数:12论文数:61被引数:570
C
C.H. Arrowsmith
H 指数:112论文数:3,098被引数:4.3万
L
Levon Halabelian
H 指数:22论文数:118被引数:1,448
P
P. Loppnau
H 指数:37论文数:276被引数:4,695
I
Irene Chau
H 指数:25论文数:80被引数:2,735
P
Pegah Ghiabi
H 指数:16论文数:88被引数:1,282
P
Peter J. Brown
H 指数:66论文数:347被引数:1.8万