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Amit Shard

national institute of pharmaceutical education and research

22H指数
100论文数
1.4K被引数
收录论文 38
发表时间
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Coumarin-sulfonamide hybrids as PKM2 activators induce metabolic reprogramming and suppress ovarian cancer cell growth香豆素-磺酰胺杂合体作为PKM2激活剂诱导代谢重编程并抑制卵巢癌细胞生长
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2026-06-01
err0
PREAI
errChatterjee, Deep Rohan; Choudhary, Gourav; Sharma, Shailendra; Rawat, Varun; Mukhopadhyay, Subhamoy; Ambast, Pranav Kumar; Kalmegh, Vaishnavi; Shard, Amit
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Rhynchophylline inhibits cluster of differentiation 36 (CD36) on endothelial cells to reduce fibrotic scar formation and enhance functional recovery after spinal cord injury钩藤碱通过抑制内皮细胞上的分化簇36（CD36）来减少纤维化瘢痕形成并促进脊髓损伤后的功能恢复
errPhytomedicine
IF8.3
err2026-04-19
err0
PREAI
errManjeet Chopra; Nidhi Singh; Meenal Verma; Divya Goyal; Saumya Kapoor; Amit Shard; Hemant Kumar
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Sustainable synthesis and biological evaluation of novel ferrocene derivatives as metabolic modulators of pyruvate kinase M2 in oral cancer新型铁卟啉衍生物的可持续合成及其作为口腔癌中丙酮酸激酶M2代谢调节剂的生物评价
errInorganic Chemistry Communications
IF5.4
err2026-04-01
err0
PREAI
errVaishnavi Kalmegh; Archit Jain; Suparna Panda; Shailendra Sharma; Saumya Kapoor; Deep Rohan Chatterjee; Moumita Ghosh Chowdhury; Pranav Kumar Ambast; Amit Shard
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Pyruvate kinase M2 - linked metabolic pathways in pain modulationM2型丙酮酸激酶相关的疼痛调控代谢通路
errDrug Discovery Today
IF7.5
err2025-11-23
err0
PREAI
errVaishnavi Kalmegh; Lahanya Guha; Deep Rohan Chatterjee; Hemant Kumar; Amit Shard
err分享
err收藏
Exploring Ugi-driven tetrazole chemistry for the discovery of pyruvate kinase M2 activators in glioblastoma management探索Ugi驱动的四唑化学在胶质瘤管理中丙酮酸激酶M2激活剂的发现
errJournal of Molecular Structure
IF4.7
err2025-11-19
err0
PREAI
errMoumita Ghosh Chowdhury; Ajit Kumar Sahu; Varun Rawat; Saumya Kapoor; Deep Rohan Chatterjee; Pranav Kumar Ambast; Amit Shard
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Thiazole-Based Tumor Pyruvate Kinase M2 Inhibitors: A Paradigm-Shifting Therapeutic Strategy Targeting Metabolic and Microbial Synergy in Colorectal Cancer基于噻唑的肿瘤丙酮酸激酶M2抑制剂：一种针对结直肠癌代谢与微生物协同作用的范式转变治疗策略
errJournal of Medicinal Chemistry
IF6.8
err2025-10-01
err0
PREAI
errMoumita Ghosh Chowdhury; Aditya A. Singh; Medha Bhattacharyya; Venkatesh Muthukumar; Saumya Kapoor; Akshay Srivastava; Hemant Kumar; Amit Shard
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err收藏
Recent progress in the development of small molecule pyruvate kinase M2 inhibitors: 2020-2025小分子丙酮酸激酶M2抑制剂的研究进展: 2020-2025
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-10-01
err0
PREAI
errDas, Rudradip; Sharma, Shailendra; Ambast, Pranav Kumar; Shard, Amit
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err收藏
Mechanism-guided discovery of chromene-chalcone hybrids targeting PKM2 and microtubules for breast cancer therapy基于机制指导的chromene-chalcone杂合分子靶向PKM2和微管用于乳腺癌治疗的发现
errBioorganic Chemistry
IF4.7
err2025-09-17
err0
PREAI
errMadhurendra Kumar Katiyar; Shubham Upadhayay; Dinesh Prasad Jalli; Vaishnavi Kalmegh; Gaurav Joshi; Vibhu Jha; Muhammad Wahajuddin; Amit Shard; Puneet Kumar; Raj Kumar
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Imidazopyrimidine-based Pyruvate Kinase M2 Activator Halts Diabetic Nephropathy Progression via Modulating Epithelial-To-Mesenchymal Transition and Fibrosis基于咪唑嘧啶的丙酮酸激酶M2激活剂通过调控上皮-间质转化和纤维化来阻止糖尿病肾病进展
errChemico-Biological Interactions
IF5.4
err2025-07-25
err0
PREAI
errMeenakshi Jain; Adil Ali Sayyed; Piyush Gondaliya; Saumya Kapoor; Deep Rohan Chatterjee; Rudradip Das; Kiran Kalia; Amit Khairnar; Amit Shard
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Synthesis, characterization, and microbiological evaluation of new triazolopyrimidine-based ferrocenes as potent antimicrobial prospects三唑嘧啶基铁卟啉衍生物的合成、表征及其作为高效抗菌候选物的微生物学评价
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2025-06-05
err0
PREAI
errKamble, Sayali; Chatterjee, Deep Rohan; Arjun, Kakad Shivani; Kapoor, Saumya; Jadhav, Madhav; Gupta, Shivam; Chowdhury, Moumita Ghosh; Das, Rudradip; Kombe, Pranav Ravindra; Borah, Sapan; Shard, Amit
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Comprehensive exploration of novel imidazopyrimidine derivatives: Design, synthesis, computational assessment, and anti-breast cancer activity
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2025-04-01
err0
PREAI
errPatel, Sagarkumar; Pulugu, Priyanka; Das, Rudradip; Chowdhury, Moumita Ghosh; Chatterjee, Deep Rohan; Srivastava, Akshay; Shard, Amit
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Carbohydrate kinase inhibition: a promising strategy in cancer treatment
errDRUG DISCOVERY TODAY
IF7.5
err2025-02-01
err0
PREAI
errJain, Archit; Das, Rudradip; Giri, Muskan; Mane, Pranita; Shard, Amit
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Modulation of the LIMK Pathway by Myricetin: A Protective Strategy Against Neurological Impairments in Spinal Cord Injury
errNEUROSPINE
IF3.6
err2024-09-30
err1
PREAI
errRoy, Abhishek; Sen, Santimoy; Das, Rudradip; Shard, Amit; Kumar, Hemant
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Modulation of tumour pyruvate kinase M2 and suppression of cancer cell proliferation using natural and synthetic antioxidants
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2024-06-01
err1
PREAI
errKapoor, Saumya; Kutre, Suraj; Joshi, Swarali; Goswami, Ashutosh; Singh, Amardeep; Teja, Parusu Kavya; Jadhav, Kishori; Tarde, Pooja; Jadhav, Rohini; Raut, Rohit; Solanki, Kajal B.; Srivastava, Akshay; Chauthe, Siddheshwar K.; Sharma, Satyasheel; Kate, Abhijeet S.; Shard, Amit
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Design and synthesis of novel quinazolinone-based pyruvate kinase M2 activators as selective inhibitors of oral cancer cells
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2024-05-01
err2
PREAI
errRathod, Bhagyashri; Joshi, Swarali; Regu, Siddulu; Manikanta, K. V. N. S.; Kumar, Hansal; Dubey, Samdisha; Chowdhury, Arnab; Shaikh, Raisa Parveen; Das, Anwesha; Patel, Sagarkumar; Satvase, Rutuja; Chatterjee, Deep Rohan; Jain, Alok; Garg, Rachana; Shard, Amit
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Rare diseases and pyruvate kinase M2: a promising therapeutic connection
errDRUG DISCOVERY TODAY
IF7.5
err2024-05-01
err1
PREAI
errKapoor, Saumya; Kalmegh, Vaishnavi; Kumar, Hemant; Mandoli, Amit; Shard, Amit
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Mechanistic Investigation of Thiazole-Based Pyruvate Kinase M2 Inhibitor Causing Tumor Regression in Triple-Negative Breast Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-02-26
err5
PREAI
errDas, Rudradip; Pulugu, Priyanka; Singh, Aditya A.; Chatterjee, Deep Rohan; Baviskar, Shraddha; Vyas, Het; Behera, Santosh Kumar; Srivastava, Akshay; Kumar, Hemant; Shard, Amit
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Targeted suppression of oral squamous cell carcinoma by pyrimidine-tethered quinoxaline derivatives
errRSC MEDICINAL CHEMISTRY
IF3.6
err2024-01-01
err2
PREAI
errChoithramani, Asmita; Das, Rudradip; Bothra, Gourav; Vatsa, Priyanka Patel; Muthukumar, Venkatesh; Bhuvana, Bombothu Kavya Sai; Kapoor, Saumya; Moola, Deepshika; Chowdhury, Moumita Ghosh; Mandoli, Amit; Shard, Amit
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Imidazopyrimidine: from a relatively exotic scaffold to an evolving structural motif in drug discovery
errRSC MEDICINAL CHEMISTRY
IF3.6
err2024-01-01
err2
PREAI
errChowdhury, Moumita Ghosh; Kalmegh, Vaishnavi; Kapoor, Saumya; Kamble, Vaishnavi; Shard, Amit
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Novel sulfonamides unveiled as potent anti-lung cancer agents via tumor pyruvate kinase M2 activation
errRSC MEDICINAL CHEMISTRY
IF3.6
err2024-01-01
err2
PREAI
errDas, Rudradip; Chatterjee, Deep Rohan; Kapoor, Saumya; Vyas, Het; Shard, Amit
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研究方向

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合作学者
合作期刊
R
Rituraj Purohit
H 指数: 56 · 论文数: 189
K
Kiran Kalia
H 指数: 46 · 论文数: 173
A
Arun K. Sinha
H 指数: 45 · 论文数: 294
R
Raj Kumar
H 指数: 41 · 论文数: 214
S
S. K. Sharma
H 指数: 41 · 论文数: 259
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