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Large-Scale Chemical-Genetic Interaction Profiling Identifies a Small-Molecule Inhibitor of Mycobacterium tuberculosis Polyketide Synthase 13 大规模化学-遗传相互作用分析鉴定出一种分枝杆菌聚酮合酶13的小分子抑制剂 Gomez, James E.; Solomon, Matthew Y.; Hunt, Diana K.; Geddes, Emily J.; Bond, Austin N.; Liu, Cong; Ulrich, Rebecca J.; Chaudhary, Pooja V.; Barkho, Sulyman; Hung, Deborah T. 分享 收藏
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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients 单核和空间转录组图谱揭示了COVID-19患者肝脏中的拓扑结构、功能及再生性器官损伤 Pita-Juarez, Yered; Karagkouni, Dimitra; Kalavros, Nikolaos; Melms, Johannes C.; Niezen, Sebastian; Delorey, Toni M.; Essene, Adam L.; Brook, Olga R.; Pant, Deepti; Skelton-Badlani, Disha; Naderi, Pourya; Huang, Pinzhu; Pan, Liuliu; Hether, Tyler; Andrews, Tallulah S.; Ziegler, Carly G. K.; Reeves, Jason; Myloserdnyy, Andriy; Chen, Rachel; Nam, Andy; Phelan, Stefan; Liang, Yan; Gregory, Mark; He, Shanshan; Patrick, Michael; Rane, Tushar; Wardhani, Aster; Amin, Amit Dipak; Biermann, Jana; Hibshoosh, Hanina; Veregge, Molly; Kramer, Zachary; Jacobs, Christopher; Yalcin, Yusuf; Phillips, Devan; Slyper, Michal; Subramanian, Ayshwarya; Ashenberg, Orr; Bloom-Ackermann, Zohar; Tran, Victoria M.; Gomez, James; Sturm, Alexander; Zhang, Shuting; Fleming, Stephen J.; Warren, Sarah; Beechem, Joseph; Hung, Deborah; Babadi, Mehrtash; Padera Jr, Robert F.; Macparland, Sonya A.; Bader, Gary D.; Imad, Nasser; Solomon, Isaac H.; Miller, Eric; Riedel, Stefan; Porter, Caroline B. M.; Villani, Alexandra-Chloe; Tsai, Linus T. -Y.; Hide, Winston; Szabo, Gyongyi; Hecht, Jonathan; Rozenblatt-Rosen, Orit; Shalek, Alex K.; Izar, Benjamin; Popov, Yury V.; Jiang, Z. Gordon; Vlachos, Ioannis S. 分享 收藏
Discovery of a Pseudomonas aeruginosa-specific small molecule targeting outer membrane protein OprH-LPS interaction by a multiplexed screen Poulsen, Bradley E.; Warrier, Thulasi; Barkho, Sulyman; Bagnall, Josephine; Romano, Keith P.; White, Tiantian; Yu, Xiao; Kawate, Tomohiko; Nguyen, Phuong H.; Raines, Kyra; Ferrara, Kristina; Golas, A. Lorelei; Fitzgerald, Michael; Boeszoermenyi, Andras; Kaushik, Virendar; Serrano-Wu, Michael; Shoresh, Noam; Hung, Deborah T. 分享 收藏
Perturbation- specific transcriptional mapping for unbiased target elucidation of antibiotics Romano, Keith P.; Bagnall, Josephine; Warrier, Thulasi; Sullivan, Jaryd; Ferrara, Kristina; Orzechowski, Marek; Nguyen, Phuong H.; Raines, Kyra; Livny, Jonathan; Shoresh, Noam; Hung, Deborah T. 分享 收藏
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Fluorogenic Probes of the Mycobacterial Membrane as Reporters of Antibiotic Action Wuo, Michael G.; Dulberger, Charles L.; Warner, Theodore C.; Brown, Robert A.; Sturm, Alexander; Ultee, Eveline; Bloom-Ackermann, Zohar; Choi, Catherine; Zhu, Junhao; Garner, Ethan C.; Briegel, Ariane; Hung, Deborah T.; Rubin, Eric J.; Kiessling, Laura L. 分享 收藏
3-Hydroxykynurenine targets kainate receptors to promote defense against infection Parada-Kusz, Margarita; Clatworthy, Anne E.; Goering, Emily R.; Blackwood, Stephanie M.; Shigeta, Jack Y.; Mashin, Eivgeni; Salm, Elizabeth J.; Choi, Catherine; Combs, Senya; Lee, Jenny S. W.; Rodriguez-Osorio, Carlos; Clish, Clary; Tomita, Susumu; Hung, Deborah T. 分享 收藏
Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis 影响结核分枝杆菌休眠期间脂质储存和利用的遗传因素 Sturm, Alexander; Sun, Penny; Avila-Pacheco, Julian; Clatworthy, Anne E.; Bloom-Ackermann, Zohar; Wuo, Michael G.; Gomez, James E.; Jin, Soomin; Clish, Clary B.; Kiessling, Laura L.; Hung, Deborah T. 分享 收藏
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants( vol 28 , pg 1083 , 2022) Welch, Nicole L.; Zhu, Meilin; Hua, Catherine; Weller, Juliane; Mirhashemi, Marzieh Ezzaty; Nguyen, Tien G.; Mantena, Sreekar; Bauer, Matthew R.; Shaw, Bennett M.; Ackerman, Cheri M.; Thakku, Sri Gowtham; Tse, Megan W.; Kehe, Jared; Uwera, Marie-Martine; Eversley, Jacqueline S.; Bielwaski, Derek A.; McGrath, Graham; Braidt, Joseph; Johnson, Jeremy; Cerrato, Felecia; Moreno, Gage K.; Krasilnikova, Lydia A.; Petros, Brittany A.; Gionet, Gabrielle L.; King, Ewa; Huard, Richard C.; Jalbert, Samantha K.; Cleary, Michael L.; Fitzgerald, Nicholas A.; Gabriel, Stacey B.; Gallagher, Glen R.; Smole, Sandra C.; Madoff, Lawrence C.; Brown, Catherine M.; Keller, Matthew W.; Wilson, Malania M.; Kirby, Marie K.; Barnes, John R.; Park, Daniel J.; Siddle, Katherine J.; Happi, Christian T.; Hung, Deborah T.; Springer, Michael; Macinnis, Bronwyn L.; Lemieux, Jacob E.; Rosenberg, Eric; Branda, John A.; Blainey, Paul C.; Sabeti, Pardis C.; Myhrvold, Cameron 分享 收藏
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High-Throughput Neutralization and Serology Assays Reveal Correlated but Highly Variable Humoral Immune Responses in a Large Population of Individuals Infected with SARS-CoV-2 in the US between March and August 2020 Zhang, Shuting; Ma, Peijun; Orzechowski, Marek; Lemmer, Allison; Rzasa, Kara; Bagnall, Josephine; Barkho, Sulyman; Chen, Michael; He, Lorri; Neitupski, Raymond; Tran, Victoria; Ackerman, Ross; Gath, Emily; Bond, Austin; Frongillo, Giana; Cleland, Thomas; Golas, Aaron; Gaca, Anthony; Fitzgerald, Michael; Kelly, Kathleen; Hazegh, Kelsey; Dumont, Larry; Hoffman, Corey; Homer, Mary; Marks, Peter; Woolley, Ann; Wong, Sharon; Gomez, James; Livny, Jonathan; Hung, Deborah 分享 收藏
Genome-wide tiled detection of circulating Mycobacterium tuberculosis cell-free DNA using Cas13 Thakku, Sri Gowtham; Lirette, Jackson; Murugesan, Kanagavel; Chen, Julie; Theron, Grant; Banaei, Niaz; Blainey, Paul C.; Gomez, James; Wong, Sharon Y.; Hung, Deborah T. 分享 收藏
Rapid Single-Shot Synthesis of the 214 Amino Acid-Long N-Terminal Domain of Pyocin S2 Saebi, Azin; Brown, Joseph S.; Marando, Victoria M.; Hartrampf, Nina; Chumbler, Nicole M.; Hanna, Stephanie; Poskus, Mackenzie; Loas, Andrei; Kiessling, Laura L.; Hung, Deborah T.; Pentelute, Bradley L. 分享 收藏
Evaluation of the Access Bio CareStart rapid SARS-CoV-2 antigen test in asymptomatic individuals tested at a community mass-testing program in Western Massachusetts Suliman, Sara; Matias, Wilfredo R.; Fulcher, Isabel R.; Molano, Francisco J.; Collins, Shannon; Uceta, Elizabeth; Zhu, Jack; Paxton, Ryan M.; Gonsalves, Sean F.; Harden, Maegan V.; Fisher, Marissa; Meldrim, Jim; Gabriel, Stacey; Franke, Molly F.; Hung, Deborah T.; Smole, Sandra C.; Madoff, Lawrence C.; Ivers, Louise C. 分享 收藏
At-home Testing and Risk Factors for Acquisition of SARS-CoV-2 Infection in a Major US Metropolitan Area 在美国主要大都市地区获得SARS-CoV-2感染的家庭检测和危险因素 Woolley, Ann E.; Dryden-Peterson, Scott; Kim, Andy; Naz-McLean, Sarah; Kelly, Christina; Laibinis, Hannah H.; Bagnall, Josephine; Livny, Jonathan; Ma, Peijun; Orzechowski, Marek; Gomez, James; Shoresh, Noam; Gabriel, Stacey; Hung, Deborah T.; Cosimi, Lisa A. 分享 收藏
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