未登录.png)
分享.png)
收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Shikonin is a novel antagonist of prostaglandin E2 receptor 4 that targets myeloid-derived suppressor cells紫草素是一种新型前列腺素E2受体4拮抗剂，靶向髓系来源抑制细胞。
Wang, Yang; Abuduaini, Naijipu; Liu, Wenjuan; Song, Yuanjun; Ke, Zunping; Wang, Xilong; Jiao, Wei; Chen, Si; Lin, Xianhua; Yu, Weiwei; Lu, Weiqiang; Feng, Bo; He, Jiacheng 分享 收藏 Design, synthesis, and biological evaluations of 5-aryl-pyrazole-3-carboxamide derivatives as selective CB2 receptor agonists for the treatment of colitisJiang, Bei-Er; He, Ying; Chen, Jie; Jiang, Xing-Wu; Qiu, Zi-Liang; Liang, Qiu-Wen; Gao, Xin-Long; Zhang, Han-Kun; Tian, Hai-Gang; Liu, Ming-Yao; Lu, Wei-Qiang; Yu, Li-Fang 分享 收藏 A structurally informed human protein-protein interactome reveals proteome-wide perturbations caused by disease mutations结构上知情的人类蛋白质-蛋白质相互作用组揭示了由疾病突变引起的蛋白质组范围的扰动Xiong, Dapeng; Qiu, Yunguang; Zhao, Junfei; Zhou, Yadi; Lee, Dongjin; Gupta, Shobhita; Torres, Mateo; Lu, Weiqiang; Liang, Siqi; Kang, Jin Joo; Eng, Charis; Loscalzo, Joseph; Cheng, Feixiong; Yu, Haiyuan 分享 收藏 Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4Guo, Mengmeng; Hu, Pan; Xie, Jiayi; Tang, Kefu; Hu, Shixiu; Sun, Jialiang; He, Yundong; Li, Jing; Lu, Weiqiang; Liu, Huirong; Liu, Mingyao; Yi, Zhengfang; Peng, Shihong 分享 收藏 PPIA dictates NRF2 stability to promote lung cancer progressionPPIA决定NRF2稳定性以促进肺癌进展Lu, Weiqiang; Cui, Jiayan; Wang, Wanyan; Hu, Qian; Xue, Yun; Liu, Xi; Gong, Ting; Lu, Yiping; Ma, Hui; Yang, Xinyu; Feng, Bo; Wang, Qi; Zhang, Naixia; Xu, Yechun; Liu, Mingyao; Nussinov, Ruth; Cheng, Feixiong; Ji, Hongbin; Huang, Jin 分享 收藏 Subtle Structural Changes across the Boundary between A2AR/A2BR Dual Antagonism and A2BR Antagonism: A Novel Class of 2-Aminopyrimidine-Based DerivativesWang, Haojie; Yang, Xinyu; Li, Yan; Ze, Shuyin; Feng, Bo; Weng, Yuan; Gao, Aoqi; Song, Gaojie; Liu, Mingyao; Xie, Qiong; Wang, Yonghui; Lu, Weiqiang 分享 收藏 Discovery of a Highly Potent Oxysterol Receptor GPR183 Antagonist Bearing the Benzo[d]thiazole Structural Motif for the Treatment of Inflammatory Bowel Disease (IBD)Zeng, Ruoqing; Fang, Meimiao; Shen, Ancheng; Chai, Xiaolei; Zhao, Yumiao; Liu, Mingyao; Zhu, Lingfeng; Rui, Weiwei; Feng, Bo; Hong, Liang; Ding, Chunyong; Song, Zilan; Lu, Weiqiang; Zhang, Ao 分享 收藏 分享 收藏 Berberrubine is a novel and selective IMPDH2 inhibitor that impairs the growth of colorectal cancerHe, Xiangli; Cui, Jiayan; Ma, Hui; Abuduaini, Naijipu; Huang, Ying; Tang, Lu; Wang, Wanyan; Zhang, Yuanyuan; Wang, Yang; Lu, Weiqiang; Feng, Bo; Huang, Jin 分享 收藏 Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemiaMa, Hui; Cui, Jiayan; Liu, Zehui; Fang, Wenqing; Lu, Sisi; Cao, Shuying; Zhang, Yuanyuan; Chen, Ji-An; Lu, Lixue; Xie, Qiong; Wang, Yonghui; Huang, Ying; Li, Kongfei; Tong, Hongyan; Huang, Jin; Lu, Weiqiang 分享 收藏 Discovery of Pyridinone Derivatives as Potent, Selective, and Orally Bioavailable Adenosine A2A Receptor Antagonists for Cancer ImmunotherapyZhu, Chenyu; Ze, Shuyin; Zhou, Ronghui; Yang, Xinyu; Wang, Haojie; Chai, Xiaolei; Fang, Meimiao; Liu, Mingyao; Wang, Yonghui; Lu, Weiqiang; Xie, Qiong 分享 收藏 Discovery of 2H-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer ImmunotherapyCheng, Zhiyuan; Wang, Yijie; Zhang, Yao; Zhang, Chan; Wang, Mengru; Wang, Wei; He, Jiacheng; Wang, Yang; Zhang, Hankun; Zhang, Qiansen; Ding, Chunyong; Wu, Deyan; Yang, Linlin; Liu, Mingyao; Lu, Weiqiang 分享 收藏 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
