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T

Taiki Abe

Tohoku University

H指数:12

被引数:631

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Phenotypic Analysis of Embryos in a Noonan Syndrome Model Mouse With the Rit1 A57G Mutation

Noonan综合征模型小鼠中Rit1 A57G突变胚胎的表型分析

MOLECULAR GENETICS & GENOMIC MEDICINE

IF1.6

2025-12-130

OAAI

Elaidic acid drives cellular senescence and inflammation via lipid raft-mediated IL-1R signaling

反式油酸通过脂筏介导的白介素1受体（IL-1R）信号通路驱动细胞衰老和炎症。

IF4.1

2025-08-060

OA

Missense and truncated variants in ERF in individuals with a Noonan-like phenotype without craniosynostosis

在具有类似Noonan综合征表型但无颅缝早闭的个体中，ERF基因的错义突变和截短变异。

SCIENTIFIC REPORTS

IF3.9

2025-04-300

OA

Dysregulation of RAS proteostasis by autosomal-dominant LZTR1 mutation induces Noonan syndrome-like phenotypes in mice

IF6.1

2024-11-220

OA

Lymphatic endothelial cell-specific NRAS p.Q61R mutant embryos show abnormal lymphatic vessel morphogenesis

HUMAN MOLECULAR GENETICS

IF3.2

2024-05-133

PRE

Mecom mutation related to radioulnar synostosis with amegakaryocytic thrombocytopenia reduces HSPCs in mice

IF7.1

2023-09-151

OAAI

LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion

CELL DEATH & DISEASE

IF9.6

2023-08-257

OAAI

Phenotypic heterogeneity in individuals with MECOM variants in 2 families

IF7.1

2022-09-1612

OAAI

Duplications in the G3 domain or switch II region in HRAS identified in patients with Costello syndrome

IF3.7

2021-10-118

OAAI

Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor α and Peroxisome Proliferator-Activated Receptor γ Coactivator 1α-Dependent Gene Expression to Increase Blood Triglyceride Levels

MOLECULAR PHARMACOLOGY

IF3

2020-11-0111

OAAI

PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice

IF5.2

2020-10-1543

OAAI

Costello syndrome model mice with aHrasG12S/+mutation are susceptible to develop house dust mite-induced atopic dermatitis

CELL DEATH & DISEASE

IF9.6

2020-08-133

OAAI

Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2019-12-0114

OAAI

LZTR1 facilitates polyubiquitination and degradation of RAS-GTPases

CELL DEATH AND DIFFERENTIATION

IF15.4

2019-07-2370

OAAI

Germline-Activating RRAS2 Mutations Cause Noonan Syndrome

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2019-06-0143

OAAI

Delineation of LZTR1 mutation-positive patients with Noonan syndrome and identification of LZTR1 binding to RAF1-PPP1CB complexes

IF3.6

2018-10-2756

PREAI

Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes

TOXICOLOGICAL SCIENCES

IF4.1

2018-06-0828

PREAI

Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid

ARCHIVES OF TOXICOLOGY

IF6.9

2016-11-1047

PREAI

PXR stimulates growth factor-mediated hepatocyte proliferation by cross-talk with the FOXO transcription factor

BIOCHEMICAL JOURNAL

IF4.3

2016-01-2526

PREAI