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Liwei Gu

university of floridaPost-doc
H指数:53
被引数:1.2万

个人简介

Dr. Gu’s research interests include the chemistry, absorption, and metabolism of food bioactives and how they affect human health. He teaches Food Analysis and Functional Foods. He advises graduate students in both Food Science and Nutrition Science Majors. Phytochemicals are plant-derived chemical compounds. “Phytonutrients” refer to phytochemicals or compounds that come from edible plants, such as flavonoids from fruits and vegetables. Elevated levels of reactive oxygen species in humans cause oxidative stress and subsequently increase the risk for cancer and cardiovascular diseases. Phytochemicals function as free radical scavengers and improve the antioxidant capacity in vivo. Dr. Gu’s research explores phytochemicals in fruits, berries, and vegetables, and tests their efficacy in quenching reactive oxygen species. Food storage and processing can alter phytochemical contents and composition and thus impact the nutritional values of many foods. Additional research will also explore new food processing techniques that can effectively preserve, concentrate, or remove phytonutrients. Upon entering the intestine, phytonutrients are degraded or transformed by intestinal bacteria into metabolites of different structures. The absorbed phytochemicals and their microbial metabolites undergo further metabolism in the human body. Dr. Gu’s research aims to understand absorption and metabolism of phytochemicals and identify factors that can affect bioavailability. Phytochemicals have a potential role to modulate gut microbiome, immune functions, and mood. Additional research will explore the efficacy and mechanisms of phytonutrients to reduce inflammations and improve overall wellbeing.

教育背景

  • 1997.01 – 2000.12

    Jiangnan University PhD

工作经历

  • 2001.01 – 2004.12

    Arkansas Children’s Nutrition Center

    Post-doc

荣誉奖项

  1. UF Research Foundation Professor(2016-2018)
  2. UF Term Professor(2017-2019)
  3. Thomson Reuters Highly Cited Researcher(2014-2016)
  4. Large Grant Leadership Awards(2021 and 2026)
Predictive models built upon annotated and validated intake biomarkers in urine using paired or unpaired analysis helped to classify cranberry juice consumers in a randomized, double-blinded, placebo-controlled, and crossover study *

在一项随机、双盲、安慰剂对照和交叉研究中,使用配对或非配对分析建立在尿液中经过注释和验证的摄入量生物标志物基础上的预测模型有助于对蔓越莓汁消费者进行分类 *

2023-01-010
OAAI
A highly efficient protein corona-based proteomic analysis strategy for the discovery of pharmacodynamic biomarkers

基于蛋白质冠的高效蛋白质组学分析策略,用于发现药效学生物标志物

2022-12-0121
OAAI
Cranberry Juice Polyphenols Inhibited the Formation of Advanced Glycation End Products in Collagens, Inhibited Advanced Glycation End Product-Induced Collagen Crosslinking, and Cleaved the Formed Crosslinks

蔓越莓汁多酚抑制胶原中晚期糖基化终产物的形成,抑制晚期糖基化终产物诱导的胶原交联,并裂解形成的交联

2022-12-0110
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