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C

Cristóbal de los Rı́os

Universidad Rey Juan Carlos
H指数:32
被引数:2,995

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Pharmacological evaluation of non-nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury

非核苷嘌呤衍生物作为P2X7拮抗剂治疗创伤性脑损伤中神经炎症的药理学评价

British Journal of Pharmacology
IF7.7
2025-06-180
OAAI
Inés Valencia; Andrea Pastor-Martínez; Céline Decouty-Pérez; Ana Belen Lopez-Rodriguez; María Álvarez-Rubal; Eva Ramos; Francesco Calzaferri; Jorge Zamorano-Fernández; Javier Giner-García; Alexis J. Palpán-Flores; Víctor Rodríguez-Domínguez; Javier Rodríguez de Cía; Borja J. Hernández-García; Alejandro Romero; Cristóbal de los Ríos; Javier Egea
C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer?s disease targeting tauopathies

冈田酸中央片段的C-糖苷类似物通过恢复PP2A-phosphatase活性发挥神经保护作用: 针对tau蛋白病的阿尔茨海默病潜在药物的合理设计

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2023-05-015
OAAI
Arribas, Raquel L.; Viejo, Lucia; Bravo, Isaac; Martinez, Minerva; Ramos, Eva; Romero, Alejandro; Garcia-Frutos, Eva M.; Janssens, Veerle; Montiel, Carmen; de los Rios, Cristobal
Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice
BRITISH JOURNAL OF PHARMACOLOGY
IF7.7
2022-02-0423
OAAI
Beamer, Edward; Morgan, James; Alves, Mariana; Menendez Mendez, Aida; Morris, Gareth; Zimmer, Bela; Conte, Giorgia; de Diego-Garcia, Laura; Alarcon-Vila, Cristina; Yiu Ng, Nico Ka; Madden, Stephen; Calzaferri, Francesco; de los Rios, Cristobal; Garcia, Antonio G.; Hamacher, Michael; Dinkel, Klaus; Pelegrin, Pablo; Henshall, David C.; Nicke, Annette; Engel, Tobias
(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease

(±)-BIGI-3h: 结合胆碱酯酶，单胺氧化酶和糖原合酶激酶3β 抑制作用的Pentatarget定向配体，具有钙通道拮抗作用和抗聚集特性，可用于阿尔茨海默氏病

ACS CHEMICAL NEUROSCIENCE
IF3.9
2021-04-0229
PREAI
Ismaili, Lhassane; Monnin, Julie; Etievant, Adeline; Arribas, Raquel L.; Viejo, Lucia; Refouvelet, Bernard; Soukup, Ondrej; Janockova, Jana; Hepnarova, Vendula; Korabecny, Jan; Kucera, Tomas; Jun, Daniel; Andrys, Rudolf; Musilek, Kamil; Baguet, Aurelie; Garcia-Frutos, Eva M.; De Simone, Angela; Andrisano, Vincenza; Bartolini, Manuela; de Los Rios, Cristobal; Marco-Contelles, Jose; Haffen, Emmanuel
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6
MOLECULES
IF4.6
2019-12-284
OAAI
Vanden Eynde, Jean Jacques; Mangoni, Arduino A.; Rautio, Jarkko; Leprince, Jerome; Azuma, Yasu-Taka; Garcia-Sosa, Alfonso T.; Hulme, Christopher; Jampilek, Josef; Karaman, Rafik; Li, Wei; Gomes, Paula A. C.; Hadjipavlou-Litina, Dimitra; Capasso, Raffaele; Geronikaki, Athina; Cerchia, Laura; Sabatier, Jean-Marc; Ragno, Rino; Tuccinardi, Tiziano; Trabocchi, Andrea; Winum, Jean-Yves; Luque, F. Javier; Prokai-Tatrai, Katalin; Spetea, Mariana; Guetschow, Michael; Kosalec, Ivan; Guillou, Catherine; Helena Vasconcelos, M.; Kokotos, George; Rastelli, Giulio; de Sousa, Maria Emilia; Manera, Clementina; Gemma, Sandra; Mangani, Stefano; Siciliano, Carlo; Galdiero, Stefania; Liu, Hong; Scott, Peter J. H.; de los Rios, Cristobal; Agrofoglio, Luigi A.; Collina, Simona; Guedes, Rita C.; Munoz-Torrero, Diego
New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-11-1431
PREAI
Malek, Rim; Arribas, Raquel L.; Palomino-Antolin, Alejandra; Totoson, Perle; Demougeot, Celine; Kobrlova, Tereza; Soukup, Ondrej; Iriepa, Isabel; Moraleda, Ignacio; Diez-Iriepa, Daniel; Godyn, Justyna; Panek, Dawid; Malawska, Barbara; Gluch-Lutwin, Monika; Mordyl, Barbara; Siwek, Agata; Chabchoub, Fakher; Marco-Contelles, Jose; Kiec-Kononowicz, Katarzyna; Egea, Javier; de los Rios, Cristobal; Ismaili, Lhassane

研究方向

暂未获取到该数据
J
José Marco‐Contelles
H 指数:56论文数:483被引数:1.2万
A
Antonio G. Garcı́a
H 指数:60论文数:531被引数:1.4万
A
Alejandro Romero
H 指数:42论文数:188被引数:5,717
J
Javier Egea
H 指数:45论文数:193被引数:7,522
A
Abdelouahid Samadi
H 指数:34论文数:139被引数:3,808
M
Mércedes Villarroya
H 指数:36论文数:143被引数:3,935
M
Manuela G. López
H 指数:62论文数:384被引数:1.5万
R
Raquel L. Arribas
H 指数:11论文数:32被引数:263
R
Rafael León
H 指数:36论文数:126被引数:5,251
R
Rocío Lajarín-Cuesta
H 指数:9论文数:25被引数:208