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Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERIC-mediated monocyte activation 白细胞CBL杂合性丧失患者的自身炎症是由组成型ERIC介导的单核细胞激活引起的 Bohlen, Jonathan; Bagaric, Ivan; Vatovec, Taja; Ogishi, Masato; Ahmed, Syed F.; Cederholm, Axel; Buetow, Lori; Sobrino, Steicy; Le Floc'h, Corentin; Arango-Franco, Carlos A.; Seabra, Luis; Michelet, Marine; Barzaghi, Federica; Leardini, Davide; Saettini, Francesco; Vendemini, Francesca; Baccelli, Francesco; Catala, Albert; Gambineri, Eleonora; Veltroni, Marinella; de la Red, Purena Aguilar; Rice, Gillian I.; Consonni, Filippo; Berteloot, Laureline; Largeaud, Laetitia; Conti, Francesca; Roullion, Cecile; Masson, Cecile; Bessot, Boris; Seeleuthner, Yoann; Le Voyer, Tom; Rinchai, Darawan; Rosain, Jeremie; Neehus, Anna-Lena; Erazo-Borras, Lucia; Li, Hailun; Janda, Zarah; Cho, En-Jui; Muratore, Edoardo; Soudee, Camille; Laine, Candice; Delabesse, Eric; Goulvestre, Claire; Ma, Cindy S.; Puel, Anne; Tangye, Stuart G.; Andre, Isabelle; Bole-Feysot, Christine; Abel, Laurent; Erlacher, Miriam; Zhang, Shen-Ping; Beziat, Vivien; Lagresle-Peyrou, Chantal; Six, Emmanuelle; Pasquet, Marlene; Alsina, Laia; Aiuti, Alessandro; Zhang, Peng; Crow, Yanick J.; Landegren, Nils; Masetti, Riccardo; Huang, Danny T.; Casanova, Jean-Laurent; Bustamante, Jacinta 分享 收藏
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Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response Vringer, Esmee; Heilig, Rosalie; Riley, Joel S.; Black, Annabel; Cloix, Catherine; Skalka, George; Montes-Gomez, Alfredo E.; Aguado, Aurore; Lilla, Sergio; Walczak, Henning; Gyrd-Hansen, Mads; Murphy, Daniel J.; Huang, Danny T.; Zanivan, Sara; Tait, Stephen W. G. 分享 收藏
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PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation Chen, Hongxia; Bai, Yunpeng; Kobayashi, Michihiro; Xiao, Shiyu; Barajas, Sergio; Cai, Wenjie; Chen, Sisi; Miao, Jinmin; Meke, Frederick Nguele; Yao, Chonghua; Yang, Yuxia; Strube, Katherine; Satchivi, Odelia; Sun, Jianmin; Ronnstrand, Lars; Croop, James M.; Boswell, H. Scott; Jia, Yuzhi; Liu, Huiping; Li, Loretta S.; Altman, Jessica K.; Eklund, Elizabeth A.; Sukhanova, Madina; Ji, Peng; Tong, Wei; Band, Hamid; Huang, Danny T.; Platanias, Leonidas C.; Zhang, Zhong-Yin; Liu, Yan 分享 收藏
PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer Nikolatou, Konstantina; Sandilands, Emma; Roman-Fernandez, Alvaro; Cumming, Erin M.; Freckmann, Eva; Lilla, Sergio; Buetow, Lori; McGarry, Lynn; Neilson, Matthew; Shaw, Robin; Strachan, David; Miller, Crispin; Huang, Danny T.; McNeish, Iain A.; Norman, James C.; Zanivan, Sara; Bryant, David M. 分享 收藏
AWT030: a first-in-class bi-functional IL-21 fusion protein selectively activates tumor infiltrated CD8 T cells and suppresses Treg cells Ye, Fan; Huang, Jianing; Chen, Sandra; Li, Ella; Jiang, Jenny; Lin, Hanna; Hua, Michael; Huang, Danny; Huang, Zoey; Kwan, Joyce; Cheng, Lili; Zhong, Ziyang 分享 收藏
eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation Schmidt, Tobias; Dabrowska, Adrianna; Waldron, Joseph A.; Hodge, Kelly; Koulouras, Grigorios; Gabrielsen, Mads; Munro, June; Tack, David C.; Harris, Gemma; McGhee, Ewan; Scott, David; Carlin, Leo M.; Huang, Danny; Le Quesne, John; Zanivan, Sara; Wilczynska, Ania; Bushell, Martin 分享 收藏
A SAFE AND HIGHLY POTENT PD-1-IL-2 FUSION (AWT020) THAT DECOUPLES THE EFFICACY AND TOXICITY OF IL-2 THERAPY Ye, Fan; Huang, Zoey; Cheng, Lili; Huang, Jianing; Chen, Sandra; Hua, Michael; Huang, Danny; Li, Ella; Jiang, Jenny; Lin, Hanna; Wang, Xin; Yue, Bella; Shi, Shirley; He, Henry; Yan, Karen; Lu, Binfeng; Zhong, Ziyang 分享 收藏
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer 肝谷氨酰胺合成酶控制体内平衡和癌症的N5-methylglutamine Villar, Victor H.; Allega, Maria Francesca; Deshmukh, Ruhi; Ackermann, Tobias; Nakasone, Mark A.; Vande Voorde, Johan; Drake, Thomas M.; Oetjen, Janina; Bloom, Algernon; Nixon, Colin; Muller, Miryam; May, Stephanie; Tan, Ee Hong; Vereecke, Lars; Jans, Maude; Blancke, Gillian; Murphy, Daniel J.; Huang, Danny T.; Lewis, David Y.; Bird, Thomas G.; Sansom, Owen J.; Blyth, Karen; Sumpton, David; Tardito, Saverio 分享 收藏
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E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK-CBL-CIN85 axis Ahmed, Syed Feroj; Buetow, Lori; Gabrielsen, Mads; Lilla, Sergio; Sibbet, Gary J.; Sumpton, David; Zanivan, Sara; Hedley, Ann; Clark, William; Huang, Danny T. 分享 收藏
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