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T

Tom Van Loy

KU Leuven
H指数:24
被引数:2,091

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Discovery of 1-(3-phenoxybenzyl)-4-(1-phenyl-1H-1,2,3-triazol-4-yl)piperidine analogues as potent and selective agonists of the human CC chemokine receptor 8

1-(3-苯氧基苄基)-4-(1-苯基-1H-1,2,3-三氮唑-4-基)哌啶类似物作为人CC趋化因子受体8的高效选择性激动剂

European Journal of Medicinal Chemistry
IF5.9
2026-09-290
PRE
Li, Qifei; Van Eynde, Wout; Van Loy, Tom; Claes, Sandra; Skarka, Adam; Andrys, Rudolf; Musilek, Kamil; Pollenus, Emilie; Schlenner, Susan M.; Schols, Dominique; Voet, Arnout; Dehaen, Wim; De Jonghe, Steven
Synthesis and evaluation of 3,5-disubstituted isothiazolo[4,5-b]pyridines, pyrazolo[4,3-b]pyridines and isothiazolo[3,4-b]pyrazines as inhibitors of PIKfyve

3,5-二取代异噻唑并[4,5-b]吡啶、吡唑并[4,3-b]吡啶和异噻唑并[3,4-b]吡嗪的合成与评价及其作为PIKfyve抑制剂的评估

Bioorganic Chemistry
IF4.7
2026-08-010
PRE
Gao, Ling-Jie; Froeyen, Mathy; Lo, Chieh-Wen; Tran, Do Hoang Nhu; Van Loy, Tom; Schols, Dominique; Rozenski, Jef; Dehaen, Wim; Einav, Shirit; De Jonghe, Steven
Surface Plasmon Resonance as a Potential Diagnostic Tool for the Detection of CXC Chemokine Receptor 4 (CXCR4) on Extracellular Vesicles

表面等离激元共振作为检测细胞外囊泡上CXC趋化因子受体4（CXCR4）的潜在诊断工具

Biosensors
IF5.6
2026-03-280
OAAI
Kaat Verleye; Sam Noppen; Arnaud Boonen; Yagmur Yildizhan; Tom Van Loy; Cindy Heens; Frank Vanderhoydonc; Cláudio Pinheiro; Paula M. Pincela Lins; Annelies Bronckaers; An Hendrix; Johannes V. Swinnen; Dragana Spasic; Jeroen Lammertyn; Christophe Pannecouque; Dominique Schols
Human and viral chemokines differentially modulate G protein signaling, β-arrestin recruitment and chemotaxis mediated by the viral G protein-coupled receptor ORF74

人类和病毒的化学引诱物蛋白（chemokines）差异性地调节病毒G蛋白偶联受体ORF74介导的G蛋白信号传导、β抑制蛋白（β-arrestin）募集和趋化性。

Cell Communication and Signaling
IF8.9
2025-11-230
OA
Qianqian Kong; Brent Van Bosstraeten; Maarten Jacquemyn; Dirk Daelemans; Steven De Jonghe; Dominique Schols; Tom Van Loy
Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size

刚性大环金属配合物作为CXCR4趋化因子受体拮抗剂: 环大小的影响

PHARMACEUTICS
IF5.5
2024-07-280
OAAI
Renard, Isaline; D'huys, Thomas; Burke, Benjamin P.; Ajoleza, Trisha; Cain, Amy N.; Funwie, Neil L.; Khan, Abid; Maples, Danny L.; Maples, Randall D.; Matz, Dallas L.; McRobbie, Graeme; Ullom, Robert; Prior, Timothy J.; Linder, Douglas P.; Van Loy, Tom; Hubin, Timothy J.; Schols, Dominique; Archibald, Stephen J.

研究方向

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D
Dominique Schols
H 指数:85论文数:878被引数:2.9万
S
Steven De Jonghe
H 指数:33论文数:236被引数:4,750
W
Wim Dehaen
H 指数:69论文数:1,045被引数:2.5万
S
Sandra Claes
H 指数:15论文数:69被引数:589
G
Guy Bormans
H 指数:72论文数:642被引数:1.9万
C
Christophe M. Deroose
H 指数:47论文数:464被引数:9,575
F
Frederik Cleeren
H 指数:23论文数:94被引数:1,797
J
Jozef Vanden Broeck
H 指数:56论文数:437被引数:1.0万
K
Katrijn Boon
H 指数:4论文数:11被引数:46
L
Lieven Stuyver
H 指数:52论文数:192被引数:1.3万