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The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit to Lead 欧洲药物化学和化学生物学联合会 (EFMC) 最佳实践倡议: 领先 Quancard, Jean; Bach, Anders; Borsari, Chiara; Craft, Russell; Gnamm, Christian; Gueret, Stephanie M.; Hartung, Ingo V.; Koolman, Hannes F.; Laufer, Stefan; Lepri, Susan; Messinger, Josef; Ritter, Kurt; Sbardella, Gianluca; Lopez, Andrea Unzue; Willwacher, Marina K.; Cox, Brian; Young, Robert J. 分享 收藏
Workflow for E3 Ligase Ligand Validation for PROTAC Development Miletic, Nebojsa; Weckesser, Janik; Mosler, Thorsten; Rathore, Rajeshwari; Hoffmann, Marina E.; Gehrtz, Paul; Schlesiger, Sarah; Hartung, Ingo V.; Berner, Nicola; Wilhelm, Stephanie; Mueller, Juliane; Adhikari, Bikash; Nemec, Vaclav; Sivashanmugam, Saran Aswathaman; Elson, Lewis; Holzmann, Hanna; Schwalm, Martin P.; Hoffmann, Lasse; Azeez, Kamal Rayees Abdul; Mueller, Susanne; Kuster, Bernhard; Wolf, Elmar; Dikic, Ivan; Knapp, Stefan 分享 收藏
Discovery and Characterization of BAY-184: A New Potent and Selective Acylsulfonamide-Benzofuran In Vivo-Active KAT6AB Inhibitor BAY-184的发现和表征: 一种新的有效和选择性的酰基磺酰胺-苯并呋喃体内活性KAT6AB抑制剂 ter Laak, Antonius; Hillig, Roman C.; Ferrara, Steven J.; Korr, Daniel; Barak, Naomi; Lienau, Philip; Herbert, Simon; Fernandez-Montalvan, Amaury Ernesto; Neuhaus, Roland; Gorjanacz, Matyas; Puetter, Vera; Badock, Volker; Bone, Wilhelm; Strathdee, Craig; Siegel, Franziska; Schatz, Christoph; Nowak-Reppel, Katrin; Doehr, Olaf; Gradl, Stefan; Hartung, Ingo V.; Meyerson, Matthew; Bouche, Lea 分享 收藏
Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer Mowat, Jeffrey; Carretero, Rafael; Leder, Gabriele; Font, Nuria Aiguabella; Neuhaus, Roland; Berndt, Sandra; Guenther, Judith; Friberg, Anders; Schaefer, Martina; Briem, Hans; Raschke, Marian; Ondozabal, Hideki Miyatake; Buchmann, Bernd; Boemer, Ulf; Kreft, Bertolt; Hartung, Ingo V.; Offringa, Rienk 分享 收藏
A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition Falkenstern, Lilia; Georgi, Victoria; Bunse, Stefanie; Badock, Volker; Husemann, Manfred; Roehn, Ulrike; Stellfeld, Timo; Fitzgerald, Mark; Ferrara, Steven; Stoeckigt, Detlef; Stresemann, Carlo; Hartung, Ingo V.; Fernandez-Montalvan, Amaury 分享 收藏
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Identification and characterization of the new generation soluble guanylate cyclase stimulator BAY-747 designed for the treatment of resistant hypertension Wunder, Frank; Stasch, Johannes-Peter; Knorr, Andreas; Mondritzki, Thomas; Brockschnieder, Damian; Becker-Pelster, Eva-Maria; Sandner, Peter; Tinel, Hanna; Redlich, Gorden; Hartung, Ingo V. V.; Vakalopoulos, Alexandros; Follmann, Markus 分享 收藏
European Medicinal Chemistry Leaders in Industry (EMCL) - On the Status and Future of Medicinal Chemistry Research in Europe Ali, Amjad; Bauser, Marcus; Bertrand, Sophie; Blackaby, Wesley; Boss, Christoph; Bossart, Martin; Hall, Adrian; Binch, Hayley; Czechtizky, Werngard; Gijsen, Harrie; Haning, Helmut; Hartung, Ingo V.; Kilburn, Paul; Lassalle, Gilbert; Luecking, Ulrich; Mack, Juergen; Missbach, Martin; Otsomaa, Leena; Torrens, Antoni; Wagner, Michael; Walter, Magnus; Weinstabl, Harald; van Hijfte, Luc; von Nussbaum, Franz 分享 收藏
New Generation of sGC Stimulators: Discovery of Imidazo[1,2-a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension Vakalopoulos, Alexandros; Wunder, Frank; Hartung, Ingo, V; Redlich, Gorden; Jautelat, Rolf; Buchgraber, Philipp; Hassfeld, Jorma; V. Gromov, Alexey; Lindner, Niels; Bierer, Donald; Gries, Jorg; Kroh, Walter; Paulsen, Holger; Mittendorf, Joachim; Lang, Dieter; Becker-Pelster, Eva; Brockschnieder, Damian; Geiss, Volker; Li, Volkhart; Straub, Alexander; Knorr, Andreas; Mondritzki, Thomas; Truebel, Hubert; Raschke, Marian; Schaefer, Martina; Thomas, Dirk; Sandner, Peter; Stasch, Johannes-Peter; Follmann, Markus 分享 收藏
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit Generation Quancard, Jean; Vulpetti, Anna; Bach, Anders; Cox, Brian; Gueret, Stephanie M.; Hartung, Ingo V.; Koolman, Hannes F.; Laufer, Stefan; Messinger, Josef; Sbardella, Gianluca; Craft, Russell 分享 收藏
Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design Krieger, Johannes; Sorrell, Fiona J.; Wegener, Ansgar A.; Leuthner, Birgitta; Machrouhi-Porcher, Fouzia; Hecht, Martin; Leibrock, Eva M.; Mueller, Juliane E.; Eisert, Jonathan; Hartung, Ingo V.; Schlesiger, Sarah 分享 收藏
Target 2035-an update on private sector contributions Ackloo, Suzanne; Antolin, Albert A.; Bartolome, Jose Manuel; Beck, Hartmut; Bullock, Alex; Betz, Ulrich A. K.; Boettcher, Jark.; Brown, Peter J.; Chaturvedi, Menorca; Crisp, Alisa; Daniels, Danette; Dreher, Jan; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Elkins, Jon; Fischer, Christian; Glendorf, Tine; Goldberg, Steven; Hartung, Ingo V.; Hillisch, Alexander; Homan, Evert; Knapp, Stefan; Koester, Markus; Kraemer, Oliver; Llaveria, Josep; Lessel, Uta; Lindemann, Sven; Linderoth, Lars; Matsui, Hisanori; Michel, Maurice; Montel, Florian; Mueller-Fahrnow, Anke; Mueller, Susanne; Owen, Dafydd R.; Saikatendu, Kumar Singh; Santhakumar, Vijayaratnam; Sanderson, Wendy; Scholten, Cora; Schapira, Matthieu; Sharma, Sujata; Shireman, Brock; Sundstrom, Michael; Todd, Matthew H.; Tredup, Claudia; Venable, Jennifer; Willson, Timothy M.; Arrowsmith, Cheryl H. 分享 收藏
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Target 2035-update on the quest for a probe for every protein Mueller, Susanne; Ackloo, Suzanne; Al Chawaf, Arij; Al-Lazikani, Bissan; Antolin, Albert; Baell, Jonathan B.; Beck, Hartmut; Beedie, Shaunna; Betz, Ulrich A. K.; Bezerra, Gustavo Arruda; Brennan, Paul E.; Brown, David; Brown, Peter J.; Bullock, Alex N.; Carter, Adrian J.; Chaikuad, Apirat; Chaineau, Mathilde; Ciulli, Alessio; Collins, Ian; Dreher, Jan; Drewry, David; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Frye, Stephen, V; Fuchs, Stephen M.; Hall, Matthew D.; Hartung, Ingo, V; Hillisch, Alexander; Hitchcock, Stephen H.; Homan, Evert; Kannan, Natarajan; Kiefer, James R.; Knapp, Stefan; Kostic, Milka; Kubicek, Stefan; Leach, Andrew R.; Lindemann, Sven; Marsden, Brian D.; Matsui, Hisanori; Meier, Jordan L.; Merk, Daniel; Michel, Maurice; Morgan, Maxwell R.; Mueller-Fahrnow, Anke; Owen, Dafydd R.; Perry, Benjamin G.; Rosenberg, Saul H.; Saikatendu, Kumar Singh; Schapira, Matthieu; Scholten, Cora; Sharma, Sujata; Simeonov, Anton; Sundstrom, Michael; Superti-Furga, Giulio; Todd, Matthew H.; Tredup, Claudia; Vedadi, Masoud; von Delft, Frank; Willson, Timothy M.; Winter, Georg E.; Workman, Paul; Arrowsmith, Cheryl H. 分享 收藏
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The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery Quancard, Jean; Bach, Anders; Cox, Brian; Craft, Russell; Finsinger, Dirk; Gueret, Stephanie M.; Hartung, Ingo V.; Laufer, Stefan; Messinger, Josef; Sbardella, Gianluca; Koolman, Hannes F. 分享 收藏
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