Francisco Hernández‐Luis

universidad nacional autónoma de mexico

24H指数

61论文数

1.9K被引数

收录论文 28

发表时间

Glyoxalase-1 Inhibition Leads to Ferroptosis Induction in Lung Cancer Cells: A Dual Mechanism of Action of Hydroxamic Acids Derived from Cysteine Glyoxalase-1抑制在肺癌细胞中诱导铁死亡：一种来源于半胱氨酸的羟肟酸的双机制作用

ChemMedChem

IF3.4

2025-11-30

OAAI

Josué Martínez-Miranda; Dolores Aguilar-Cázares; Angélica Flores–Flores; Miguel Ángel Santos-Contreras; José S. López-González; Rodrigo Aguayo-Ortiz; Rogélio Hernández-Pando; Francisco Hernández-Luis

Alchemical free energy-based optimization of quinazoline derivatives as potent EGFR inhibitors with cytotoxic activity 基于炼金学自由能的喹唑啉衍生物作为具有细胞毒活性的有效EGFR抑制剂的优化

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2025-07-01

OAAI

Martinez-Ortega, U.; Aguayo-Ortiz, R.; Aguilar-Cazares, D.; Guerrero-Molina, E. D.; Aguilar-Martinez, V.; Moreno-Rodriguez, A.; Lopez-Gonzalez, J. S.; Vazquez-Ramos, J. M.; Hernandez-Luis, F.

Advances in ferrocene photosensitizers: illuminating new avenues in the medicinal chemistry of cancer 铁氧环光敏剂的研究进展：为癌症药物化学开辟新途径

Medicinal Chemistry Research

IF3.1

2025-06-11

OAAI

Diego I. Figueroa-Figueroa; Francisco Hernández-Luis

Exploring Quinazoline Nitro-Derivatives as Potential Antichagasic Agents: Synthesis and In Vitro Evaluation

MOLECULES

IF4.6

2024-09-23

OAAI

Vazquez, Citlali; Matus-Meza, Audifas-Salvador; Nunez-Moreno, Oswaldo; Barbosa-Sanchez, Brenda Michelle; Farias-Gutierrez, Victor Manuel; Mendoza-Conde, Mariana; Hernandez-Luis, Francisco; Saavedra, Emma

Compounds Consisting of Quinazoline, Ibuprofen, and Amino Acids with Cytotoxic and Anti-Inflammatory Effects

CHEMMEDCHEM

IF3.4

2024-02-28

OAAI

Garduno-Villavicencio, Luis Roberto; Martinez-Ortega, Ulises; Ortiz-Sanchez, Elizabeth; Tinajero-Rodriguez, Jose Manuel; Hernandez-Luis, Francisco

Synthesis of Quinazolin-2,4,6-triamine Derivatives as Non-purine Xanthine Oxidase Inhibitors and Exploration of Their Toxicological Potential

CHEMMEDCHEM

IF3.4

2023-08-29

OAAI

Lopez-Sanchez, Marcela A.; Garcia-Rodriguez, Maria del Carmen; Aguayo-Ortiz, Rodrigo; Hernandez-Cruz, Estefani; Figueroa-Figueroa, Diego I.; Hernandez-Luis, Francisco

In Silico Characterization of Masitinib Interaction with SARS-CoV-2 Main Protease 马赛替尼与SARS-CoV-2主要蛋白酶相互作用的计算机表征

CHEMMEDCHEM

IF3.4

2021-07-09

OAAI

Martinez-Ortega, Ulises; Figueroa-Figueroa, Diego, I; Hernandez-Luis, Francisco; Aguayo-Ortiz, Rodrigo

Design, Synthesis and Evaluation of 2,4-Diaminoquinazoline Derivatives as Potential Tubulin Polymerization Inhibitors

CHEMMEDCHEM

IF3.4

2020-08-26

OAAI

Herrera-Vazquez, Frida S.; Matadamas-Martinez, Felix; Aguayo-Ortiz, Rodrigo; Dominguez, Laura; Ramirez-Apan, Teresa; Yepez-Mulia, Lilian; Hernandez-Luis, Francisco

Systematic search for benzimidazole compounds and derivatives with antileishmanial effects

MOLECULAR DIVERSITY

IF3.8

2018-05-10

OAAI

Carlos Sanchez-Salgado, Juan; Bilbao-Ramos, Pablo; Auxiliadora Dea-Ayuela, Maria; Hernandez-Luis, Francisco; Bolas-Fernandez, Francisco; Medina-Franco, Jose L.; Rojas-Aguirre, Yareli

Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies 布氏锥虫磷酸丙糖异构酶的物种特异性失活: 动力学和分子动力学研究

MOLECULES

IF4.6

2017-11-24

OAAI

Vazquez-Raygoza, Alejandra; Cano-Gonzalez, Lucia; Velazquez-Martinez, Israel; Josue Trejo-Soto, Pedro; Castillo, Rafael; Hernandez-Campos, Alicia; Hernandez-Luis, Francisco; Oria-Hernandez, Jesus; Castillo-Villanueva, Adriana; Avitia-Dominguez, Claudia; Sierra-Campos, Erick; Valdez-Solana, Monica; Tellez-Valencia, Alfredo

Synthesis and molecular docking of N′-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-05-01

PREAI

Hernandez-Vazquez, Eduardo; Salgado-Barrera, Sandybel; Jose Ramirez-Espinosa, Juan; Estrada-Soto, Samuel; Hernandez-Luis, Francisco

ENP11, a potential CB1R antagonist, induces anorexia in rats

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2015-08-01

PREAI

Mendez-Diaz, Monica; Amancio-Belmont, Octavio; Hernandez-Vazquez, Eduardo; Ruiz-Contreras, Alejandra E.; Hernandez-Luis, Francisco; Prospero-Garcia, Oscar

1,5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-07-01

PREAI

Hernandez-Vazquez, Eduardo; Castaneda-Arriaga, Romina; Jose Ramirez-Espinosa, Juan; Noel Medina-Campos, Omar; Hernandez-Luis, Francisco; Pedraza Chaverri, Jose; Estrada-Soto, Samuel

Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-05-01

PREAI

Mendoza-Martinez, Cesar; Correa-Basurto, Jose; Nieto-Meneses, Rocio; Marquez-Navarro, Adrian; Aguilar-Suarez, Rocio; Dinora Montero-Cortes, Miriam; Nogueda-Torres, Benjamin; Suarez-Contreras, Erick; Galindo-Sevilla, Norma; Rojas-Rojas, Angela; Rodriguez-Lezama, Alejandro; Hernandez-Luis, Francisco

Antileishmanial activity of quinazoline derivatives: Synthesis, docking screens, molecular dynamic simulations and electrochemical studies

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-03-01

PREAI

Mendoza-Martinez, Cesar; Galindo-Sevilla, Norma; Correa-Basurto, Jose; Manuel Ugalde-Saldivar, Victor; Georgina Rodriguez-Delgado, Rosa; Hernandez-Pineda, Jessica; Padierna-Mota, Cecilia; Flores-Alamo, Marcos; Hernandez-Luis, Francisco

In vitro antiparasitic activity of new thiosemicarbazones in strains of Trypanosoma cruzi

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-11-01

PREAI

Moreno-Rodriguez, Adriana; Maria Salazar-Schettino, Paz; Luis Bautista, Juan; Hernandez-Luis, Francisco; Torrens, Hugo; Guevara-Gomez, Yolanda; Pina-Canseco, Socorro; Bucio Torres, Martha; Cabrera-Bravo, Margarita; Mendoza Martinez, Cesar; Perez-Campos, Eduardo

Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2013-11-01

PREAI

Hernandez-Vazquez, Eduardo; Aguayo-Ortiz, Rodrigo; Jose Ramirez-Espinosa, Juan; Estrada-Soto, Samuel; Hernandez-Luis, Francisco

Exploring the interplay of physicochemical properties, membrane permeability and giardicidal activity of some benzimidazole derivatives

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2012-06-01

PREAI

Hernandez-Covarrubias, Carlos; Vilchis-Reyes, Miguel A.; Yepez-Mulia, Lilian; Sanchez-Diaz, Remedios; Navarrete-Vazquez, Gabriel; Hernandez-Campos, Alicia; Castillo, Rafael; Hernandez-Luis, Francisco

Diversity in the supramolecular interactions of 5,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole with modified cyclodextrins: Implications for physicochemical properties and antiparasitic activity

CARBOHYDRATE POLYMERS

IF12.5

2012-01-01

PREAI

Rojas-Aguirre, Yareli; Castillo, Ivan; Hernandez, David J.; Nogueda-Torres, Benjamin; Marquez-Navarro, Adrian; Villalobos, Juan C.; Sanchez-Bartez, Francisco; Sanchez-Torres, Luvia; Gracia-Mora, Isabel; Castillo, Rafael; Hernandez-Luis, Francisco

Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of some benzimidazole derivatives with trichomonicidal activity

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2011-08-01

PREAI

Perez-Villanueva, Jaime; Medina-Franco, Jose L.; Caulfield, Thomas R.; Hernandez-Campos, Alicia; Hernandez-Luis, Francisco; Yepez-Mulia, Lilian; Castillo, Rafael

研究方向