Luís C. López - Publications, H-index & Citations

Luís C. López

university of stuttgart

61H指数

156论文数

1.0W被引数

收录论文 77

发表时间

Successful treatment of neonatal COQ2 deficiency with 4-hydroxybenzoic acid Münch, J.; Strahleck, T.; Seibt, A.; Smits, S.H.J.; Herbrich, S.; Hohnecker, A.K.; Wilhelm, B.; Rafat, N.; Reihle, C.; Stirnkorb, C.; et al. 使用4-羟基苯甲酸成功治疗新生儿COQ2缺乏症。Brain 2026, awag023. [Google Scholar] [CrossRef]

Brain

IF11.7

2026-04-01

PREAI

Munch, Juliane; Strahleck, Thomas; Seibt, Annette; Smits, Sander H. J.; Herbrich, Sonja; Hohnecker, Ann-Katrin; Wilhelm, Bernhard; Rafat, Neysan; Reihle, Christof; Stirnkorb, Christian; Parczyk, Nadiya; Himmelreich, Nastassja; Dinwiddie, April; Mayatepek, Ertan; Herebian, Diran; Lopez, Luis C.; Distelmaier, Felix

Preclinical and first-in-human evidence of 4-hydroxybenzoic acid for mitochondrial COQ2 deficiency Distelmaier, F.; Corral-Sarasa, J.; Jiménez-Sánchez, L.; Díaz-Casado, M.E.; Rohmann, M.; Seibt, A.; Herebian, D.; Smits, S.H.J.; Münch, J.; Mayatepek, E.; et al. 4-羟基苯甲酸对线粒体COQ2缺乏的预临床和首次人体证据。Brain 2025, awaf334. [Google Scholar] [CrossRef]

Brain

IF11.7

2025-09-10

OAAI

Felix Distelmaier; Julia Corral-Sarasa; Laura Jiménez-Sánchez; María Elena Díaz-Casado; Melanie Rohmann; Annette Seibt; Diran Herebian; Sander H J Smits; Juliane Münch; Ertan Mayatepek; Jörg Breitkreutz; Ralf A Husain; Sergio López-Herrador; Pilar González-García; Luis C López; null

β-Resorcylic acid prevents MASLD in ob/ob mice by modulating lipid metabolism and inflammation in the liver β-雷索里酸通过调节肝脏的脂质代谢和炎症，预防ob/ob小鼠发生代谢相关脂肪性肝病。

Pharmacological Research

IF10.5

2025-08-09

OAAI

Sergio López-Herrador; Sara Torres-Rusillo; Pilar González-García; Laura Jiménez-Sánchez; Julia Corral-Sarasa; Mohammed Bakkali; M. Elena Díaz-Casado; Luis C. López

The treatment of primary CoQ deficiency requires the targeting of multiple pathogenic mechanisms 原发性辅酶Q缺乏症的治疗需要针对多种致病机制。

Communications Medicine

IF6.3

2025-07-10

OAAI

Pilar González-García; Laura Jiménez-Sánchez; Julia Corral-Sarasa; Sergio López-Herrador; Sara Torres-Rusillo; María Elena Díaz-Casado; Luis C. López

Coenzyme Q10 deficiency disrupts lipid metabolism by altering cholesterol homeostasis in neurons

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2025-03-01

OAAI

Pesini, Alba; Barriocanal-Casado, Eliana; Compagnoni, Giacomo Monzio; Hidalgo-Gutierrez, Agustin; Yanez, Giussepe; Bakkali, Mohammed; Chhonker, Yashpal S.; Kleiner, Giulio; Larrea, Delfina; Tadesse, Saba; Lopez, Luis Carlos; Murry, Daryl J.; Di Fonzo, Alessio; Area-Gomez, Estela; Quinzii, Catarina M.

Sexual dimorphism on the acute effect of exercise in the morning vs. evening: A randomized crossover study 早晨与傍晚运动对急性效应的性别二态性：一项随机交叉研究

JOURNAL OF SPORT AND HEALTH SCIENCE

IF10.3

2024-12-01

OAAI

Raquel Sevilla-Lorente; Andres Marmol-Perez; Pilar Gonzalez-Garcia; María de las Nieves Rodríguez-Miranda; Blanca Riquelme-Gallego; Jerónimo Aragon-Vela; Juan Manuel Martinez-Gálvez; Pablo Molina-Garcia; Juan Manuel A. Alcantara; José Garcia-Consuegra; Sara Cogliati; Luis Miguel Salmeron; Jesús R. Huertas; Luis C. Lopez; Jonatan R. Ruiz; Francisco José Amaro-Gahete

4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease

CELL REPORTS

IF6.9

2024-05-01

OAAI

Corral-Sarasa, Julia; Martinez-Galvez, Juan Manuel; Gonzalez-Garcia, Pilar; Wendling, Olivia; Jimenez-Sanchez, Laura; Lopez-Herrador, Sergio; Quinzii, Catarina M.; Diaz-Casado, Maria Elena; Lopez, Luis C.

Whole-Exome Sequencing Study of Fibroblasts Derived From Patients With Cerebellar Ataxia Referred to Investigate CoQ10 Deficiency

NEUROLOGY-GENETICS

IF3.7

2023-04-01

OAAI

Monfrini, Edoardo; Pesini, Alba; Biella, Fabio; Sobreira, Claudia F. R.; Emmanuele, Valentina; Brescia, Gloria; Carlos Lopez, Luis; Tadesse, Saba; Hirano, Michio; Comi, Giacomo P.; Maria Quinzii, Catarina; Di Fonzo, Alessio

Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport

JOURNAL OF PINEAL RESEARCH

IF6.3

2022-08-28

OAAI

Florido, Javier; Martinez-Ruiz, Laura; Rodriguez-Santana, Cesar; Lopez-Rodriguez, Alba; Hidalgo-Gutierrez, Agustin; Cottet-Rousselle, Cecile; Lamarche, Frederic; Schlattner, Uwe; Guerra-Librero, Ana; Aranda-Martinez, Paula; Acuna-Castroviejo, Dario; Lopez, Luis C.; Escames, Germaine

Exposure to non-persistent pesticides, BDNF, and behavioral function in adolescent males: Exploring a novel effect biomarker approach

ENVIRONMENTAL RESEARCH

IF7.7

2022-08-01

OAAI

Rodriguez-Carrillo, Andrea; D'Cruz, Shereen C.; Mustieles, Vicente; Suarez, Beatriz; Smagulova, Fatima; David, Arthur; Peinado, Francisco; Artacho-Cordon, Francisco; Lopez, Luis C.; Arrebola, Juan P.; Olea, Nicolas; Fernandez, Mariana F.; Freire, Carmen

Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings

ANTIOXIDANTS

IF6.6

2021-10-26

OAAI

Gonzalez-Garcia, Pilar; Barriocanal-Casado, Eliana; Diaz-Casado, Maria Elena; Lopez-Herrador, Sergio; Hidalgo-Gutierrez, Agustin; Lopez, Luis C.

β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight

BIOMEDICINES

IF3.9

2021-10-13

OAAI

Hidalgo-Gutierrez, Agustin; Barriocanal-Casado, Eliana; Diaz-Casado, Maria Elena; Gonzalez-Garcia, Pilar; Zenezini Chiozzi, Riccardo; Acuna-Castroviejo, Dario; Lopez, Luis Carlos

Abnormalities of hydrogen sulfide and glutathione pathways in mitochondrial dysfunction

JOURNAL OF ADVANCED RESEARCH

IF13

2021-01-01

OAAI

Quinzii, Catarina M.; Lopez, Luis C.

Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism

HUMAN MOLECULAR GENETICS

IF3.2

2020-09-25

OAAI

Gonzalez-Garcia, Pilar; Hidalgo-Gutierrez, Agustin; Mascaraque, Cristina; Barriocanal-Casado, Eliana; Bakkali, Mohammed; Ziosi, Marcello; Botagoz Abdihankyzy, Ussipbek; Sanchez-Hernandez, Sabina; Escames, Germaine; Prokisch, Holger; Martin, Francisco; Quinzii, Catarina M.; Lopez, Luis C.

The Paradox of Coenzyme Q10 in Aging

NUTRIENTS

IF5

2019-09-14

OAAI

Elena Diaz-Casado, M.; Quiles, Jose L.; Barriocanal-Casado, Eliana; Gonzalez-Garcia, Pilar; Battino, Maurizio; Lopez, Luis C.; Varela-Lopez, Alfonso

Hydroxytyrosol influences exercise-induced mitochondrial respiratory complex assembly into supercomplexes in rats

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2019-04-01

PREAI

Casuso, Rafael A.; Al-Fazazi, Saad; Hidalgo-Gutierrez, Agustin; Carlos Lopez, Luis; Plaza-Diaz, Julio; Rueda-Robles, Ascension; Huertas, Jesus R.

Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease

EBIOMEDICINE

IF10.8

2019-04-01

OAAI

Barriocanal-Casado, Eliana; Hidalgo-Gutierrez, Agustin; Raimundo, Nuno; Gonzalez-Garcia, Pilar; Acuna-Castroviejo, Dario; Escames, Germaine; Lopez, Luis C.

Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

IF3.8

2019-03-14

PREAI

Sayed, Ramy K. A.; Fernandez-Ortiz, Marisol; Diaz-Casado, Maria E.; Aranda-Martinez, Paula; Fernandez-Martinez, Jose; Guerra-Librero, Ana; Escames, Germaine; Lopez, Luis C.; Alsaadawy, Reem M.; Acuna-Castroviejo, Dario

β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9R239X mice

EMBO MOLECULAR MEDICINE

IF8.3

2018-11-27

OAAI

Hidalgo-Gutierrez, Agustin; Barriocanal-Casado, Eliana; Bakkali, Mohammed; Elena Diaz-Casado, M.; Sanchez-Maldonado, Laura; Romero, Miguel; Sayed, Ramy K.; Prehn, Cornelia; Escames, Germaine; Duarte, Juan; Acuna-Castroviejo, Dario; Lopez, Luis C.

Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis

SCIENTIFIC REPORTS

IF3.9

2018-09-18

OAAI

Rodriguez-Hidalgo, Maria; Luna-Sanchez, Marta; Hidalgo-Gutierrez, Agustin; Barriocanal-Casado, Eliana; Mascaraque, Cristina; Acuna-Castroviejo, Dario; Rivera, Margarita; Escames, Germaine; Lopez, Luis C.

研究方向