未登录 Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau 使用阿尔茨海默病脑匀浆和C322A或C322S重组tau蛋白进行tau丝的串联放大 Santambrogio, Alessia; Lovestam, Sofia; Metrick II, Michael A.; Lohr, Thomas; Xu, Peifeng; Gallagher, Nicholas C. T.; Ghetti, Bernardino; Caughey, Byron; Scheres, Sjors H. W.; Vendruscolo, Michele 分享 收藏
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Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease Heller, Gabriella T.; Aprile, Francesco A.; Michaels, Thomas C. T.; Limbocker, Ryan; Perni, Michele; Ruggeri, Francesco Simone; Mannini, Benedetta; Lohr, Thomas; Bonomi, Massimiliano; Camilloni, Carlo; De Simone, Alfonso; Felli, Isabella C.; Pierattelli, Roberta; Knowles, Tuomas P. J.; Dobson, Christopher M.; Vendruscolo, Michele 分享 收藏
An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase 内在无序的基序调节p47衔接子和p97 AAA ATPase之间的相互作用 Conicella, Alexander E.; Huang, Rui; Ripstein, Zev A.; Nguyen, Ai; Wang, Eric; Lohr, Thomas; Schuck, Peter; Vendruscolo, Michele; Rubinstein, John L.; Kay, Lewis E. 分享 收藏
Promoting transparency and reproducibility in enhanced molecular simulations 提高增强分子模拟的透明度和再现性 Bonomi, Massimiliano; Bussi, Giovanni; Camilloni, Carlo; Tribello, Gareth A.; Banas, Pavel; Barducci, Alessandro; Bernetti, Mattia; Bolhuis, Peter G.; Bottaro, Sandro; Branduardi, Davide; Capelli, Riccardo; Carloni, Paolo; Ceriotti, Michele; Cesari, Andrea; Chen, Haochuan; Chen, Wei; Colizzi, Francesco; De, Sandip; De La Pierre, Marco; Donadio, Davide; Drobot, Viktor; Ensing, Bernd; Ferguson, Andrew L.; Filizola, Marta; Fraser, James S.; Fu, Haohao; Gasparotto, Piero; Gervasio, Francesco Luigi; Giberti, Federico; Gil-Ley, Alejandro; Giorgino, Toni; Heller, Gabriella T.; Hocky, Glen M.; Iannuzzi, Marcella; Invernizzi, Michele; Jelfs, Kim E.; Jussupow, Alexander; Kirilin, Evgeny; Laio, Alessandro; Limongelli, Vittorio; Lindorff-Larsen, Kresten; Lohr, Thomas; Marinelli, Fabrizio; Martin-Samos, Layla; Masetti, Matteo; Meyer, Ralf; Michaelides, Angelos; Molteni, Carla; Morishita, Tetsuya; Nava, Marco; Paissoni, Cristina; Papaleo, Elena; Parrinello, Michele; Pfaendtner, Jim; Piaggi, Pablo; Piccini, GiovanniMaria; Pietropaolo, Adriana; Pietrucci, Fabio; Pipolo, Silvio; Provasi, Davide; Quigley, David; Raiteri, Paolo; Raniolo, Stefano; Rydzewski, Jakub; Salvalaglio, Matteo; Sosso, Gabriele Cesare; Spiwok, Vojtech; Sponer, Jiri; Swenson, David W. H.; Tiwary, Pratyush; Valsson, Omar; Vendruscolo, Michele; Voth, Gregory A.; White, Andrew 分享 收藏
Effects of α-tubulin acetylation on microtubule structure and stability Α-微管蛋白乙酰化对微管结构和稳定性的影响 Eshun-Wilson, Lisa; Zhang, Rui; Portran, Didier; Nachury, Maxence V.; Toso, Daniel B.; Lohr, Thomas; Vendruscolo, Michele; Bonomi, Massimiliano; Fraser, James S.; Nogales, Eva 分享 收藏
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THE HIGHS AND LOWS OF TRANSLATIONAL DRUG DEVELOPMENT: ANTIBODY-MEDIATED INHIBITION OF ADAMTS-5 FOR OSTEOARTHRITIS DISEASE MODIFICATION Larkin, J.; Lohr, T.; Elefante, L.; Shearin, J.; Matico, R.; Su, J-L.; Xue, Y.; Liu, F.; Rossman, E. I.; Renninger, J.; Wu, X.; Abberley, L.; Miller, R. E.; Foulcer, S.; Chaudhary, K. W.; Genell, C.; Murphy, D.; Tran, P. B.; Apte, S.; Malfait, A-M.; Maier, C. C.; Matheny, C. J. 分享 收藏
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Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT) Deng, Hongfeng; O'Keefe, Heather; Davie, Christopher P.; Lind, Kenneth E.; Acharya, Raksha A.; Franklin, G. Joseph; Larkin, Jonathan; Matico, Rosalie; Neeb, Michael; Thompson, Monique M.; Lohr, Thomas; Gross, Jeffrey W.; Centrella, Paolo A.; O'Donovan, Gary K.; Bedard, Katie L. (Sargent); van Vloten, Kurt; Mataruse, Sibongile; Skinner, Steven R.; Belyanskaya, Svetlana L.; Carpenter, Tiffany Y.; Shearer, Todd W.; Clark, Matthew A.; Cuozzo, John W.; Arico-Muendel, Christopher C.; Morgan, Barry A. 分享 收藏
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