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Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2 Indrigo, Marzia; Morella, Ilaria; Orellana, Daniel; d'Isa, Raffaele; Papale, Alessandro; Parra, Riccardo; Gurgone, Antonia; Lecca, Daniela; Cavaccini, Anna; Tigaret, Cezar M.; Cagnotto, Alfredo; Jones, Kimberley; Brooks, Simon; Ratto, Gian Michele; Allen, Nicholas D.; Lelos, Mariah J.; Middei, Silvia; Giustetto, Maurizio; Carta, Anna R.; Tonini, Raffaella; Salmona, Mario; Hall, Jeremy; Thomas, Kerrie; Brambilla, Riccardo; Fasano, Stefania 分享 收藏
Cdk12 maintains the integrity of adult axons by suppressing actin remodeling Townsend, L. N.; Clarke, H.; Maddison, D.; Jones, K. M.; Amadio, L.; Jefferson, A.; Chughtai, U.; Bis, D. M.; Zuechner, S.; Allen, N. D.; van Naters, W. van der Goes; Peters, O. M.; Smith, G. A. 分享 收藏
Soluble mutant huntingtin drives early human pathogenesis in Huntington's disease Miguez, Andres; Gomis, Cinta; Vila, Cristina; Monguio-Tortajada, Marta; Fernandez-Garcia, Sara; Bombau, Georgina; Galofre, Mireia; Garcia-Bravo, Maria; Sanders, Phil; Fernandez-Medina, Helena; Poquet, Blanca; Salado-Manzano, Cristina; Roura, Santiago; Alberch, Jordi; Segovia, Jose Carlos; Allen, Nicholas D.; Borras, Francesc E.; Canals, Josep M. 分享 收藏
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The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer- related alterations of the endosomal-autophagic-lysosomal system 合成的TRPML1激动剂ML-SA1挽救了阿尔茨海默氏症相关的内体-自噬-溶酶体系统的改变 Somogyi, Aleksandra; Kirkham, Emily D.; Lloyd-Evans, Emyr; Winston, Jincy; Allen, Nicholas D.; Mackrill, John J.; Anderson, Karen E.; Hawkins, Phillip T.; Gardiner, Sian E.; Waller-Evans, Helen; Sims, Rebecca; Boland, Barry; O'Neill, Cora 分享 收藏
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Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation Liu, Qian; Telezhkin, Vsevolod; Jiang, Wenkai; Gu, Yu; Wang, Yan; Hong, Wei; Tian, Weiming; Yarova, Polina; Zhang, Gaofeng; Lee, Simon Ming-yuen; Zhang, Peng; Zhao, Min; Allen, Nicholas D.; Hirsch, Emilio; Penninger, Josef; Song, Bing 分享 收藏
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FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease Goold, Robert; Hamilton, Joseph; Menneteau, Thomas; Flower, Michael; Bunting, Emma L.; Aldous, Sarah G.; Porro, Antonio; Vicente, Jose R.; Allen, Nicholas D.; Wilkinson, Hilary; Bates, Gillian P.; Sartori, Alessandro A.; Thalassinos, Konstantinos; Balmus, Gabriel; Tabrizi, Sarah J. 分享 收藏
PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease-protective variant PLCγ2 R522 Maguire, Emily; Menzies, Georgina E.; Phillips, Thomas; Sasner, Michael; Williams, Harriet M.; Czubala, Magdalena A.; Evans, Neil; Cope, Emma L.; Simss, Rebecca; Howell, Gareth R.; Lloyd-Evans, Emyr; Williams, Julie; Allen, Nicholas D.; Taylor, Philip R. 分享 收藏
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons Steg, Leonard C.; Shireby, Gemma L.; Imm, Jennifer; Davies, Jonathan P.; Franklin, Alice; Flynn, Robert; Namboori, Seema C.; Bhinge, Akshay; Jeffries, Aaron R.; Burrage, Joe; Neilson, Grant W. A.; Walker, Emma M.; Perfect, Leo W.; Price, Jack; McAlonan, Grainne; Srivastava, Deepak P.; Bray, Nicholas J.; Cope, Emma L.; Jones, Kimberley M.; Allen, Nicholas D.; Pishva, Ehsan; Dempster, Emma L.; Lunnon, Katie; Mill, Jonathan; Hannon, Eilis 分享 收藏
Abnormal scaffold attachment factor 1 expression and localization in spinocerebellar ataxias and Huntington's chorea Buckner, Nicola; Kemp, Kevin C.; Scott, Helen L.; Shi, Gongyu; Rivers, Caroline; Gialeli, Andriana; Wong, Liang-Fong; Cordero-LLana, Oscar; Allen, Nicholas; Wilkins, Alastair; Uney, James B. 分享 收藏
A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria (vol 295, pg 3285, 2020) Scott, Helen L.; Buckner, Nicola; Fernandez-Albert, Francesc; Pedone, Elisa; Postiglione, Lorena; Shi, Gongyu; Allen, Nicholas; Wong, Liang-Fong; Magini, Lorenzo; Marucci, Lucia; O'Sullivan, Gregory A.; Cole, Sarah; Powell, Justin; Maycox, Peter; Uney, James B. 分享 收藏
A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria Scott, Helen L.; Buckner, Nicola; Fernandez-Albert, Francesc; Pedone, Elisa; Postiglione, Lorena; Shi, Gongyu; Allen, Nicholas; Wong, Liang-Fong; Magini, Lorenzo; Marucci, Lucia; O'Sullivan, Gregory A.; Cole, Sarah; Powell, Justin; Maycox, Peter; Uney, James B. 分享 收藏
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