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Afshin Zarghi

Shahid Beheshti University of Medical Sciences

37H指数
261论文数
8.3K被引数
收录论文 45
发表时间
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Mitochondria-mediated anticancer effects of two previously characterized COX-2 inhibitors in hepatocellular carcinoma两种先前表征的COX-2抑制剂在肝细胞癌中的线粒体介导的抗肿瘤作用
errMolecular and Cellular Biochemistry
IF3.7
err2026-09-11
err0
PREAI
errRoya Mirzaei; Mahsa Manafi Varkiani; Mona Moosavi; Reza Habibi; Fereshteh Niknam; Mahsa Azami Movahed; Afshin Zarghi; Jalal Pourahmad
err分享
err收藏
Protein-Protein Interaction as an Efficient Target to Inhibit HIV-1 Integrase蛋白质-蛋白质相互作用作为抑制HIV-1整合酶的高效靶点
errArchiv der Pharmazie
IF3.6
err2026-05-22
err0
PREAI
errAfshin Zarghi; Zahra Hajimahdi
err分享
err收藏
Synthesis of some novel 2-(imidazolyl)quinoline derivatives as DNA intercalating agents, evaluation of their cytotoxicity, interaction with calf thymus DNA (ctDNA) via spectroscopic studies, drug-likeness, ADMET prediction, docking and MD simulation合成一些新型的2-(咪唑基)喹啉衍生物作为DNA嵌入剂，评估其细胞毒性，通过光谱学研究其与牛胸腺DNA(ctDNA)的相互作用，药物相似性，ADMET预测，对接和分子动力学模拟
errJournal of Molecular Structure
IF4.7
err2025-11-19
err0
PREAI
errNegar Omidkhah; Jamshidkhan Chamani; Fereshte Dashti Motlagh; Afshin Zarghi; Farzin Hadizadeh; Razieh Ghodsi
err分享
err收藏
Synthesis, biological evaluation, and molecular dynamic studies of novel quinoline-based hydroxamic acid derivatives as HDAC inhibitor and anticancer agents合成、生物评价及分子动力学研究：作为HDAC抑制剂和抗癌剂的 Novel Quinoline-based Hydroxamic Acid Derivatives
errCHEMICAL PAPERS
IF2.5
err2025-11-01
err0
PREAI
errOmidkhah, Negar; Hadizadeh, Farzin; Zarghi, Afshin; Ghodsi, Razieh
err分享
err收藏
Recent Advances in Therapeutic Potential of Dual-Acting Aromatase/COX-2双作用芳构酶/COX-2在治疗潜力方面的最新进展
errANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
IF3
err2025-03-26
err0
PREAI
errAliabadi, Ali; Tajdari, Mobina; Fakharinia, Sara; Ashrafizadeh, Niusha Sadat; Bayanati, Maryam; Mahboubi-Rabbani, Mohammad; Zarghi, Afshin
err分享
err收藏
New indolin-2-ones, possessing sunitinib scaffold as HDAC inhibitors and anti-cancer agents with potential VEGFR inhibition activity; design, synthesis and biological evaluation新型吲哚啉-2-酮，具有舒尼替尼骨架作为HDAC抑制剂和具有潜在VEGFR抑制活性的抗肿瘤剂；设计、合成与生物评价
errBIOORGANIC CHEMISTRY
IF4.7
err2025-03-01
err0
PREAI
errYousefian, Mozhdeh; Hashemi, Maryam; Eskandarpour, Vahid; Zarghi, Afshin; Hadizadeh, Farzin; Ghodsi, Razieh
err分享
err收藏
Design, synthesis, molecular dynamics studies and biological evaluations of 4-hydroxy-5-pyrrolinone-3-carbohydrazides as HIV-1 integrase inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS
IF4.1
err2024-12-01
err0
errOAAI
errKarimi, Nafiseh; Beirami, Amirreza Dowlati; Roudsari, Rouhollah Vahabpour; Hajimahdi, Zahra; Zarghi, Afshin
err分享
err收藏
Selective COX-2 inhibitors as anticancer agents: a patent review (2018-2023)
errEXPERT OPINION ON THERAPEUTIC PATENTS
IF4.6
err2024-07-03
err4
PREAI
errMahboubi-Rabbani, Mohammad; Abdolghaffari, Amir Hossein; Ghesmati, Mahsa; Amini, Ali; Zarghi, Afshin
err分享
err收藏
Design, synthesis, biological evaluation and molecular docking study of novel chalcone-based hydroxamic acids possessing a central 2, 4-dimethy pyrrole linker as potential HDAC (Histone Deacetylase) inhibitors and anticancer agents
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2024-06-01
err8
PREAI
errYousefian, Mozhdeh; Hashemi, Maryam; Eskandarpour, Vahid; Hadizadeh, Farzin; Zarghi, Afshin; Ghodsi, Razieh
err分享
err收藏
Investigation of anti-cancer effects of new pyrazino[1,2-a]benzimidazole derivatives on human glioblastoma cells through 2D in vitro model and 3D-printed microfluidic device
errLIFE SCIENCES
IF5.1
err2022-08-01
err6
PREAI
errRahimifard, Mahban; Bagheri, Zeinab; Hadjighassem, Mahmoudreza; Jaktaji, Razieh Pourahmad; Behroodi, Ebrahim; Haghi-Aminjan, Hamed; Movahed, Mahsa Azami; Latifi, Hamid; Hosseindoost, Saereh; Zarghi, Afshin; Pourahmad, Jalal
err分享
err收藏
Antiproliferative activity of new derivatives of pyrazino[1,2-a]benzimidazole: Integrated cell-based assay and computational studies with divalent magnesium, iron, and copper ions
errJOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
IF2.8
err2022-07-06
err1
PREAI
errRahimifard, Mahban; Jalalimanesh, Nafiseh; Movahed, Mahsa A.; Hadjighassem, Mahmoudreza; Jaktaji, Razieh Pourahmad; Bagheri, Zeinab; Pourahmad, Jalal; Zarghi, Afshin
err分享
err收藏
Assessment of cytotoxic effects of new derivatives of pyrazino[1,2-a] benzimidazole on isolated human glioblastoma cells and mitochondria
errLIFE SCIENCES
IF5.1
err2021-12-01
err10
PREAI
errRahimifard, Mahban; Haghi-Aminjan, Hamed; Hadjighassem, Mahmoudreza; Jaktaji, Razieh Pourahmad; Bagheri, Zeinab; Movahed, Mahsa Azami; Zarghi, Afshin; Pourahmad, Jalal
err分享
err收藏
Correlation Between Low-Dose Chest Computed Tomography and RT-PCR Results for the Diagnosis of COVID-19: A Report of 27,824 Cases in Tehran, Iran
errACADEMIC RADIOLOGY
IF3.9
err2021-12-01
err12
errOAAI
errZali, Alireza; Sohrabi, Mohammad-Reza; Mahdavi, Ali; Khalili, Nastaran; Taheri, Morteza Sanei; Maher, Ali; Sadoughi, Mohammadmehdi; Zarghi, Afshin; Ziai, Seyed Ali; Shabestari, Abbas Arjmand; Bakhshayeshkaram, Mehrdad; Haghighatkhah, Hamidreza; Salevatipour, Babak; Abrishami, Alireza; Raoufi, Masoomeh; Dehghan, Pooneh; Bagheri, Arash Khameneh; Khoshnoud, Reza Jalili; Hanani, Khatereh
err分享
err收藏
Therapeutic potential of chelerythrine as a multi-purpose adjuvant for the treatment of COVID-19
errCELL CYCLE
IF3.4
err2021-09-29
err33
errOAAI
errValipour, Mehdi; Zarghi, Afshin; Ebrahimzadeh, Mohammad Ali; Irannejad, Hamid
err分享
err收藏
Design, synthesis and biological evaluation of novel indanone containing spiroisoxazoline derivatives with selective COX-2 inhibition as anticancer agents
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2021-02-01
err22
PREAI
errAbolhasani, Hoda; Zarghi, Afshin; Movahhed, Tahereh Komeili; Abolhasani, Ahmad; Daraei, Bahram; Dastmalchi, Siavoush
err分享
err收藏
Lipoxygenase Inhibitors as Cancer Chemopreventives: Discovery, Recent Developments and Future Perspectives
errCURRENT MEDICINAL CHEMISTRY
IF3.5
err2021-02-01
err14
PREAI
errMahboubi-Rabbani, Mohammad; Zarghi, Afshin
err分享
err收藏
Selective COX-2 inhibitors as anticancer agents: a patent review (2014-2018)
errEXPERT OPINION ON THERAPEUTIC PATENTS
IF4.6
err2019-05-27
err76
PREAI
errRabbani, Sayyed Mohammad Ismail Mahboubi; Zarghi, Afshin
err分享
err收藏
A randomized, double-blind, placebo-controlled investigation of BCc1 nanomedicine effect on survival and quality of life in metastatic and non-metastatic gastric cancer patients
errJOURNAL OF NANOBIOTECHNOLOGY
IF12.6
err2019-04-10
err16
errOAAI
errHafizi, Maryam; Kalanaky, Somayeh; Moaiery, Hassan; Khayamzadeh, Maryam; Noorian, Sajad; Kaveh, Vahid; Gharib, Behrooz; Foudazi, Hossein; Razavi, Mohsen; Jenabian, Arash; Salimi, Saeid; Sereshki, Mohammad Mahdi Adib; Mirzaei, Hamid Reza; Zarghi, Afshin; Fakharzadeh, Saideh; Nazaran, Mohammad Hassan; Akbari, Mohammad Esmaeil
err分享
err收藏
Targeting the mitochondrial apoptosis pathway by a newly synthesized COX-2 inhibitor in pediatric ALL lymphocytes
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2018-10-11
err13
PREAI
errAghvami, Marjan; Salimi, Ahmad; Eshghi, Peyman; Zarei, Mohammad H.; Farzaneh, Shabnam; Sattari, Fatemeh; Zarghi, Afshin; Pourahmad, Jalal
err分享
err收藏
An investigation into the ability of alendronate ion pairs to increase oral absorption
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2017-07-01
err13
PREAI
errSamiei, Nasim; Foroutan, Seyed Mohsen; Razipour, Fattaneh; Zarghi, Afshin; Shafaati, Alireza
err分享
err收藏

研究方向

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合作学者
合作期刊
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Abolghasem Jouyban
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Jamshidkhan Chamani
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Mehdi Hedayati
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