George R. Young - Publications, H-index & Citations

George R. Young

Humboldt University of Berlin

31H指数

131论文数

4.6K被引数

收录论文 35

发表时间

Temporal loss of En1 during limb development causes distinct phenotypes En1在肢体发育期间的时间性缺失导致不同的表型

GENES & DEVELOPMENT

IF7.7

2026-05-01

PREAI

Ringel, Alessa R.; Benetti, Natalia; Magg, Andreas; Groll, Fabian; Schopflin, Robert; Kuhnlein, Mira; Stiege, Asita Carola; Fischer, Ute; Wittler, Lars; Game, Laurence; Lorenz, Stephan; Young, George; Mundlos, Stefan; Allou, Lila

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability 亲电化合物筛选鉴定出GPX4依赖性铁死亡为衰老的易损性

Nature Cell Biology

IF19.1

2026-04-24

OAAI

Mariantonietta D’Ambrosio; Matthew E. H. White; Efthymios S. Gavriil; Laura Bousset; Jodie Birch; Aleksandra Gruevska; Emiliano Pasquini; Manuel Colucci; Winnie Fong; Simone Mosole; Aurora Valdata; Dimitris Veroutis; Katie Tyson; Vikas Ranvir; Sandra Prokosch; Joaquim Pombo; Aoki Ardisson; Sanjay Khadayate; George Young; Alex Montoya; Georgia Roumelioti; Jack Houghton; Jianan Lu; Pavel V. Shliaha; Elena De Vita; Santiago Vernia; Vassilis G. Gorgoulis; Suchira Gallage; Mathias Heikenwälder; Zoe Hall; Andrea Alimonti; Iain A. McNeish; Edward W. Tate; Jesús Gil

Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors 多模态成像揭示了一种溶酶体药物贮库，该贮库驱动PARP抑制剂分布的异质性

Nature Communications

IF15.7

2026-03-17

OAAI

Carmen R. Moncayo; Restuadi Restuadi; Guanying Zhang; Daniel Marks; Paula Ortega-Prieto; Emily Doherty; Nathalie Lambie; Chad Whilding; Ivan Andrew; Alex Montoya; Bhavik Patel; Katie Tyson; Betheney R. Pennycook; Lauren Pendergast; Vincen Wu; Zoltan Takats; Nik Matthews; George R. Young; Priyanka Verma; Pavel Shliaha; Laurence Game; Boris Lenhard; Iain McNeish; Christina Fotopoulou; Alexis R. Barr; Paula Cunnea; Zoe Hall; Louise Fets

Retraction Note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy 撤稿注意: 针对内源性逆转录病毒的抗体促进肺癌免疫治疗

Nature

IF48.5

2026-01-14

OAAI

Kevin W. Ng; Jesse Boumelha; Katey S. S. Enfield; Jorge Almagro; Hongui Cha; Oriol Pich; Takahiro Karasaki; David A. Moore; Roberto Salgado; Monica Sivakumar; George Young; Miriam Molina-Arcas; Sophie de Carné Trécesson; Panayiotis Anastasiou; Annika Fendler; Lewis Au; Scott T. C. Shepherd; Carlos Martínez-Ruiz; Clare Puttick; James R. M. Black; Thomas B. K. Watkins; Hyemin Kim; Seohee Shim; Nikhil Faulkner; Jan Attig; Selvaraju Veeriah; Neil Magno; Sophia Ward; Alexander M. Frankell; Maise Al Bakir; Emilia L. Lim; Mark S. Hill; Gareth A. Wilson; Daniel E. Cook; Nicolai J. Birkbak; Axel Behrens; Nadia Yousaf; Sanjay Popat; Allan Hackshaw; Crispin T. Hiley; Kevin Litchfield; Nicholas McGranahan; Mariam Jamal-Hanjani; James Larkin; Se-Hoon Lee; Samra Turajlic; Charles Swanton; Julian Downward; George Kassiotis

CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency, and cell death

SCIENCE ADVANCES

IF12.5

2025-12-19

PREAI

Chammas, Paul; Xie, Sheila Q.; Sepulveda-Rincon, Lessly P.; Leeke, Bryony J.; Dore, Marian H.; Dormann, Dirk; Wagner, Ryan T.; Chang, Ning; Jones, Peter L.; McManus, Michael T.; Karimi, Mohammad M.; Young, George; Percharde, Michelle

Astrocytic RNA editing regulates the host immune response to alpha-synuclein 星形胶质细胞RNA编辑调节宿主对α-突触核蛋白的免疫反应

SCIENCE ADVANCES

IF12.5

2025-04-11

OAAI

D'Sa, Karishma; Choi, Minee L.; Wagen, Aaron Z.; Seto-Salvia, Nuria; Kopach, Olga; Evans, James R.; Rodrigues, Margarida; Lopez-Garcia, Patricia; Lachica, Joanne; Clarke, Benjamin E.; Singh, Jaijeet; Ghareeb, Ali; Bayne, James; Grant-Peters, Melissa; Garcia-Ruiz, Sonia; Chen, Zhongbo; Rodriques, Samuel; Athauda, Dilan; Gustavsson, Emil K.; Taliun, Sarah A. Gagliano; Toomey, Christina; Reynolds, Regina H.; Young, George; Strohbuecker, Stephanie; Warner, Thomas; Rusakov, Dmitri A.; Bryant, Clare; Klenerman, David A.; Ryten, Mina

Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion SARS-CoV-2亚基因组RNA的出现，增强了病毒适应性和免疫逃逸能力

PLOS BIOLOGY

IF7.2

2025-01-21

OAAI

Mears, Harriet V.; Young, George R.; Sanderson, Theo; Harvey, Ruth; Barrett-Rodger, Jamie; Penn, Rebecca; Cowton, Vanessa; Furnon, Wilhelm; De Lorenzo, Giuditta; Crawford, Marg; Snell, Daniel M.; Fowler, Ashley S.; Chakrabarti, Anob M.; Hussain, Saira; Gilbride, Ciaran; Emmott, Edward; Finsterbusch, Katja; Luptak, Jakub; Peacock, Thomas P.; Nicod, Jerome; Patel, Arvind H.; Palmarini, Massimo; Gandhi, Sonia; Swanton, Charles; Bauer, David L. V.

Competition shapes the landscape of X-chromosome-linked genetic diversity

NATURE GENETICS

IF31.8

2024-07-26

OAAI

Buenaventura, Teresa; Bagci, Hakan; Patrascan, Ilinca; Graham, Joshua J.; Hipwell, Kelsey D.; Oldenkamp, Roel; King, James W. D.; Urtasun, Jesus; Young, George; Mouzo, Daniel; Gomez-Cabrero, David; Rowland, Benjamin D.; Panne, Daniel; Fisher, Amanda G.; Merkenschlager, Matthias

The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes

NAR CANCER

IF3.2

2023-07-26

OAAI

Kazachenka, Anastasiya; Loong, Jane Hc; Attig, Jan; Young, George R.; Ganguli, Piyali; Devonshire, Ginny; Grehan, Nicola; Ciccarelli, Francesca D.; Fitzgerald, Rebecca C.; Kassiotis, George

Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-07-17

OAAI

Attig, Jan; Pape, Judith; Doglio, Laura; Kazachenka, Anastasiya; Ottina, Eleonora; Young, George R.; Enfield, Katey S. S.; Aramburu, Iker Valle; Ng, Kevin W.; Faulkner, Nikhil; Bolland, William; Papayannopoulos, Venizelos; Swanton, Charles; Kassiotis, George

Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London 独立的SARS-CoV-2人员测试保护了伦敦西北部的学术和医疗机构

LANCET

IF88.5

2023-07-01

OAAI

Bailey, Chris; Sanderson, Theo; Townsley, Hermaleigh; Goldman, Jacki; Black, James R. M.; Young, George; Goldstone, Robert; Fowler, Ashley S.; Ward, Sophia; Jackson, Deborah J.; Cubitt, Laura; Dearing, Vicky; O'Neil, Olga; Crawford, Marg; Snell, Daniel; Finadis, Makis; Edwards, Amelia; Perez-Lloret, Jimena; Gahir, Joshua; Carr, Edward J.; Riddell, Andy; Aitken, Jim; Ambrose, Karen; Sawyer, Chelsea; O'Reilly, Nicola; Caidan, Simon; Wu, Mary Y.; Walker, Philip A.; Hindmarsh, Steve; Howell, Michael; Jordan, Andrew; Fleming, James; Houlihan, Catherine; Nastouli, Eleni; Moores, Rachel; Hsu, Desmond; Papineni, Padmasayee; Corrah, Tumena; Gilson, Richard; MacRae, James; Hubank, Michael; Van As, Nicholas; Turajlic, Samra; Beale, Rupert; Levi, Marcel; Barrell, Sam; Williams, Bryan; Gamblin, Steve; Nicod, Jerome; Gandhi, Sonia; Bauer, David L., V; Wall, Emma C.; Swanton, Charles

SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export

PLOS PATHOGENS

IF4.9

2022-08-25

OAAI

Hall, Ross; Guedan, Anabel; Yap, Melvyn W.; Young, George R.; Harvey, Ruth; Stoye, Jonathan P.; Bishop, Kate N.

Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control

NATURE COMMUNICATIONS

IF15.7

2021-09-22

OAAI

Cottee, Matthew A.; Beckwith, Sean L.; Letham, Suzanne C.; Kim, Sarah J.; Young, George R.; Stoye, Jonathan P.; Garfinkel, David J.; Taylor, Ian A.

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses

IMMUNITY

IF26.3

2021-09-01

OAAI

Tang, Qiannan; Rigby, Rachel E.; Young, George R.; Hvidt, Astrid Korning; Davis, Tanja; Tan, Tiong Kit; Bridgeman, Anne; Townsend, Alain R.; Kassiotis, George; Rehwinkel, Jan

E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion

ONCOGENE

IF7.3

2021-06-18

OAAI

Ottina, Eleonora; Panova, Veera; Doglio, Laura; Kazachenka, Anastasiya; Cornish, Georgina; Kirkpatrick, Joanna; Attig, Jan; Young, George R.; Litchfield, Kevin; Lesluyes, Tom; Van Loo, Peter; Swanton, Charles; MacRae, James; Tuting, Thomas; Kassiotis, George

Gv1, a Zinc Finger Gene Controlling Endogenous MLV Expression

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2021-02-09

OAAI

Young, George R.; Ferron, Aaron K. W.; Panova, Veera; Eksmond, Urszula; Oliver, Peter L.; Kassiotis, George; Stoye, Jonathan P.

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-01-08

OAAI

Nakagawa, Rinako; Toboso-Navasa, Amparo; Schips, Marta; Young, George; Bhaw-Rosun, Leena; Llorian-Sopena, Miriam; Chakravarty, Probir; Sesay, Abdul Karim; Kassiotis, George; Meyer-Hermann, Michael; Calado, Dinis Pedro

Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses

PLOS GENETICS

IF3.7

2020-06-11

OAAI

Yap, Melvyn W.; Young, George R.; Varnaite, Renata; Morand, Serge; Stoye, Jonathan P.

Antibody-induced internalisation of retroviral envelope glycoproteins is a signal initiation event

PLOS PATHOGENS

IF4.9

2020-05-26

OAAI

Panova, Veera; Attig, Jan; Young, George R.; Stoye, Jonathan P.; Kassiotis, George